Coming from a year-long benzo habit (2mg Diclazepam twice daily at this time) I searched for a substitute to slowly taper down with. Came across Meclonazepam (still not sure if it's the N-Methyl or 3-Methyl compound as the vendor's page wasn't 100% clear, tending to the former) and decided to swap the evening serving o...
Meclonazepam
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 2 corroborating sources
- partial dose data
- duration data present
- 17 combo interactions documented
- classified Tentative
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 2 corroborating sources
- partial dose data
- duration data present
- 17 combo interactions documented
- classified Tentative
Summary
A benzodiazepine related to clonazepam discovered by Hoffman-LaRoche in the 1960s. Potentially useful in treating schistosomiasis. Has been sold on the grey market as a recreational drug but has not seen widespread popularity.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | - | 3-6mg | - | 6-12mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Peak | Total |
|---|---|---|---|
| Oral | 20-60 min | 9-15 hrs | 9-15 hrs |
Effect Profile
1 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Benzodiazepine
6.6
Strong+
7/10
Strong euphoria and anxiolysis with mild cognitive impairment, low sedation
Anxiolysis
×3
8
anxiolytic
reduced anxiety
muscle relaxant
Sedation / Relaxation
×2
3
sedation
Motor / Cognitive Impairment
×1
4
amnesia
confusion
Euphoria / Mood Lift
×1
10
euphoria
cognitive euphoria
disinhibition
Based on reports from:
Tolerance
Build-up
develops over 1–4 weeks of daily use; hypnotic tolerance faster than anxiolytic tolerance
Reset
weeks to months depending on half-life and duration of use; taper recommended
Tolerance Decay
Full tolerance
3d
Half tolerance
37d
Baseline
~60d
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
Positive
- Anxiolytic
- Muscle Relaxant
- Stimulation
Negative
- Increased heart rate
- Pupil dilation
- Insomnia
- Sedative
- Dystaxia
- Hypnotic
- Sedation
Positive
- Reduced anxiety
- Euphoria
- Cognitive euphoria
- Wakefulness
- Empathy
Negative
- Amnesia
- Anxiety
- Confusion
- Compulsive redosing
- Time distortion
Positive
- Increased music appreciation
- Color enhancement
- Tactile enhancement
- Brightened colour
Negative
- Light sensitivity
- Appetite suppression
- Dehydration
- Disinhibition
- Dulled perception
- Drifting
Combinations
Cross-Check Meclonazepam with another substanceCommunity Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.
Erowid 1 report 1 neutral visit
Meclonazepam's nerd page
Pharmacology, chemical data, effect profiles, and more
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Helpful Links
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