Summary
A benzodiazepine related to clonazepam discovered by Hoffman-LaRoche in the 1960s. Potentially useful in treating schistosomiasis. Has been sold on the grey market as a recreational drug but has not seen widespread popularity.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | - | 3-6mg | - | 6-12mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Peak | After Effects | Total |
|---|---|---|---|---|
| Oral | 20-60 min | 9.0-15.0 hrs | 1.0-6.0 hrs | 540-0 min |
Tolerance
Build-up
develops over 1–4 weeks of daily use; hypnotic tolerance faster than anxiolytic tolerance
Reset
weeks to months depending on half-life and duration of use; taper recommended
Effects
Positive
- Anxiolytic
- Muscle Relaxant
- Stimulation
Negative
- Increased heart rate
- Pupil dilation
- Insomnia
- Sedative
- Dystaxia
- Hypnotic
- Sedation
Positive
- Reduced anxiety
- Euphoria
- Cognitive euphoria
- Wakefulness
- Empathy
Negative
- Amnesia
- Anxiety
- Confusion
- Compulsive redosing
- Time distortion
Positive
- Increased music appreciation
- Color enhancement
- Tactile enhancement
- Brightened colour
Negative
- Light sensitivity
- Appetite suppression
- Dehydration
- Disinhibition
- Dulled perception
- Drifting