Meclonazepam Stats & Data
O=N(=O)c1ccc2NC(=O)C(C)N=C(c3ccccc3Cl)c2c1LMUVYJCAFWGNSY-VIFPVBQESA-NPharmacology
DrugBankHistory & Culture
Meclonazepam was first synthesized by a research team at Hoffmann-La Roche during the 1970s as a benzodiazepine derivative structurally related to clonazepam. Early investigations identified potential anti-parasitic applications against Schistosoma mansoni, the parasitic flatworm responsible for schistosomiasis, though this therapeutic avenue was never developed to the point of clinical approval. The compound was never marketed as a pharmaceutical product. It later emerged on the grey market as a designer drug, though it has not achieved widespread popularity within recreational drug communities.
Effect Profile
Curated + 1 ReportsStrong euphoria and anxiolysis with mild cognitive impairment, low sedation
Tolerance & Pharmacokinetics
drugs.wikiTolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.