For the past 2 years, I have been consistently prescribed oxycodone in various forms for a broken back, the subsequent surgery, and post-surgical pain. I have developed quite a tolerance as you might imagine, requiring over 200mg a day to alleviate the pain.
Metaxalone
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 2 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- PubChem toxicity data
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 2 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- PubChem toxicity data
Aliases: Skelaxin
Summary
Metaxalone is a centrally acting skeletal-muscle relaxant, used to relieve pain and discomfort caused by muscle injuries.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 400-800mg | 800-1600mg | 1600-2400mg | 2400mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Peak | Total |
|---|---|---|---|
| Oral | 15-45 min | 4-8 hrs | 4-8 hrs |
Add to PsychonautWiki Journal
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Import this file as custom substances
and you get "Metaxalone (Substance Search)" with every
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versions.
Name
Metaxalone
Unit
mg
Description
Metaxalone Source: SubstanceSearch (substancesearch.com) Oral dose (mg): light 400-800 · common 800-1600 · strong 1600-2400 · heavy 2400+ Oral duration: onset 15-45m · peak 4-8h · total 4-8h · after-effects 1-8h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 1200 mg (Oral).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Build-up
develops over 1–4 weeks of regular use
Reset
days to weeks depending on duration of use
Tolerance Decay
Full tolerance
3d
Half tolerance
8d
Baseline
~14d
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
Aggregated from 21 Erowid experience reports
Positive Effects 8
Anxiety Suppression
42.9%
70%
Sedation
38.1%
70%
Stimulation
19.0%
70%
Focus Enhancement
19.0%
70%
Euphoria
19.0%
70%
Pain Relief
14.3%
70%
Empathy
14.3%
70%
Music Enhancement
14.3%
70%
Adverse Effects 4
Nausea
28.6%
70%
Increased Heart Rate
23.8%
70%
Sweating
14.3%
70%
Confusion
14.3%
70%
Community Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.
Erowid 8 reports 1 positive 3 neutral 4 cautionary visit
In my early teens I was prescribed a drug commonly known as Skelaxin, or Metaxalone, as a secondary treatment for the chronic anxiety I suffer. It worked fairly well; it did its job to the best of its ability, however due to my tendency to abuse the medications I was prescribed in the absence of marijuana or any of the...
I have been on a lot of medications for a variety of issues, and suffer from anorexia nervosa. Recently I began getting knots in my muscles and spasms and went to visit the doctor. I asked to be put on a muscle relaxer to get some relief, and she prescribed me Skelaxin.
After some consideration of various sites and pieces of information, I decided to try out insulfating 800mg of Skelaxin as a possible means to a body high. The idea had been previously raised by my boyfriend.
I am an experienced drug user having tried LSD, XTC, cocaine. speed, opiates, and various pharmaceuticals and herbal drugs. I try not to take any one substance for a long period of time and I am interested in trying new chemicals to see what experiences are possible.
I came across a bottle from a friend, I didn't find too much info on experience so I started out small. On 8/19/08 at 2pm I took 1/2 pill, I took the other half one hour later at 3pm. 3pm I felt slightly light headed and a little excited, mostly from the new experience.
I recently had a muscle strain in my lower back from working. I got a script for the muscle relaxer Skelaxin. I thought, you know--a pill is a pill, so at first I snorted one tab. I didn't expirence any kind of a high or buzz, but I was slightly relaxed.
I have been having some problems with head and neck pain for a while, so my doctor prescribed me Flexeril (Cyclobenzaprine) the other day. I remember using some muscle relaxant a few years ago and it was reasonably enjoyable. Nothing over the top. Just a calm experience.
Bluelight 1 thread 1 neutral visit
So mother has some of these 800mg Skelaxin's laying around. Supposedly to just relax muscles and chill twitches and spasms. I read up, and there does not seem to be a ton of recreational value. I found a couple people claiming it potentiates opiates. So I set out to explore. Took 2.
Pill Identifiers
4
known pill identifiers on record — view imprints, colors, shapes, and images
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Metaxalone's nerd page
Pharmacology, chemical data, effect profiles, and more
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Helpful Links
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