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    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    Methcathinone

    Aliases: Mc, Cat, Kat, Jeff, M-kat

    Stimulant Research-chemical

    Summary TheDrug.Wiki PsychonautWiki

    Methcathinone is a Schedule I controlled substance internationally and in the US. Illicit synthesis using potassium permanganate oxidation of ephedrine/pseudoephedrine has been associated with manganese-induced neurotoxicity resembling Parkinson's disease symptoms. Causes severe dehydration and increased perspiration requiring constant hydration to prevent rhabdomyolysis.

    Dose Information TheDrug.Wiki PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 50-100mg 100-200mg 200-300mg 300mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects
    Oral 10-30 min 30-60 min 1-2 hrs 1-2 hrs 2-6 hrs
    Insufflated 5-10 min 15-30 min 1-2 hrs 1-2 hrs 2-6 hrs

    Effect Profile

    17 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Empathogen 5.6
    Strong 6/10

    Moderate stimulation and euphoria with mild empathy and sensory enhancement

    Empathy / Social Openness ×3
    5
    empathy enhancement increased sociability
    Euphoria / Mood Elevation ×2
    6
    physical euphoria cognitive euphoria
    Stimulation ×1
    7
    stimulation wakefulness teeth grinding increased heart rate
    Sensory Enhancement ×1
    5
    tactile enhancement increased libido
    Stimulant 5.9
    Strong 6/10

    Strong anxiety/jitters and focus with moderate euphoria, mild stimulation

    Stimulation / Energy ×3
    5
    stimulation wakefulness
    Euphoria / Mood Lift ×2
    7
    physical euphoria cognitive euphoria motivation enhancement
    Focus / Productivity ×2
    9
    focus enhancement analysis enhancement motivation enhancement thought acceleration
    ⚠ Anxiety / Jitters ×1
    10
    anxiety paranoia increased heart rate teeth grinding vasoconstriction
    Based on reports from:
    Erowid Experience Reports PsychonautWiki Methcathinone
    View methodology →

    Tolerance

    Build-up develops rapidly, often within a single session; compulsive redosing common
    Reset a few days for acute tolerance

    Tolerance Decay

    Full tolerance 2d Half tolerance 4d Baseline ~10d

    Rapid tolerance is commonly reported with repeated use over days; rough decay to baseline over ~1–2 weeks is inferred from community reports and stimulant analogues. Data quality is limited and interindividual variability is high.

    Cross-Tolerances

    Amphetamines
    50%
    Other cathinones
    60%

    Effects Erowid

    Aggregated from 17 Erowid experience reports

    Positive Effects 4

    Stimulation 82.4% 70%
    Euphoria 58.8% 70%
    Focus Enhancement 35.3% 70%
    Empathy 17.6% 70%

    Adverse Effects 8

    Anxiety 47.1% 70%
    Confusion 29.4% 70%
    Seizure 17.6% 70%
    Psychosis 17.6% 70%
    Pupil Dilation 17.6% 70%
    Nausea 17.6% 70%
    Muscle Tension 17.6% 70%
    Headache 17.6% 70%

    Combinations TripSit

    Methcathinone's nerd page Pharmacology, chemical data, effect profiles, and more
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    Helpful Links

    📘 Experience Reports 📖 TheDrug.Wiki 📖 PsychonautWiki