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    ๐Ÿงช This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    Methcathinone Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 3 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • 29 combo interactions documented
    • classified Research-chemical

    Aliases: Mc, Cat, Kat, Jeff, M-kat

    Summary dose.wiki PsychonautWiki

    Methcathinone is a Schedule I controlled substance internationally and in the US. Illicit synthesis using potassium permanganate oxidation of ephedrine/pseudoephedrine has been associated with manganese-induced neurotoxicity resembling Parkinson's disease symptoms. Causes severe dehydration and increased perspiration requiring constant hydration to prevent rhabdomyolysis.

    Dose Information dose.wiki PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 50-100mg 100-200mg 200-300mg 300mg+
    Light Common Strong Heavy
    Sources

    Oral

    Dose ladder — dose.wiki, PsychonautWiki

    Onset, Duration & After-effects dose.wiki PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 10-30 min 30-60 min 1-2 hrs 1-2 hrs 2-6 hrs 2.67-5.5 hrs
    Insufflated 5-10 min 15-30 min 1-2 hrs 1-2 hrs 2-6 hrs 2.33-4.67 hrs

    Effect Profile

    13 reports

    Scores (0–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Empathogen 5.6
    Strong 6/10

    Moderate stimulation and euphoria with mild empathy and sensory enhancement

    Empathy / Social Openness ×3
    5
    empathy enhancement increased sociability
    Euphoria / Mood Elevation ×2
    6
    physical euphoria cognitive euphoria
    Stimulation ×1
    7
    stimulation wakefulness teeth grinding increased heart rate
    Sensory Enhancement ×1
    5
    tactile enhancement increased libido
    Stimulant 5.9
    Strong 6/10

    Strong focus with strong anxiety/jitters, moderate euphoria, mild stimulation

    Stimulation / Energy ×3
    5
    stimulation wakefulness
    Euphoria / Mood Lift ×2
    7
    physical euphoria cognitive euphoria motivation enhancement
    Focus / Productivity ×2
    9
    focus enhancement analysis enhancement motivation enhancement thought acceleration
    ⚠ Anxiety / Jitters ×1
    10
    anxiety paranoia increased heart rate teeth grinding vasoconstriction
    Based on reports from:

    Tolerance

    Build-up develops rapidly, often within a single session; compulsive redosing common
    Reset a few days for acute tolerance

    Tolerance Decay

    Full tolerance 2d Half tolerance 4d Baseline ~10d

    Rapid tolerance is commonly reported with repeated use over days; rough decay to baseline over ~1โ€“2 weeks is inferred from community reports and stimulant analogues. Data quality is limited and interindividual variability is high.

    Cross-Tolerances

    Other cathinones

    Effects Erowid

    Aggregated from 13 single-substance Erowid experience reports; 4 Erowid reports where another drug was taken too are left out

    Each bar shows the share of analyzed reports whose text mentions that effect — a mention is not always a first-hand experience (fear of an effect or something witnessed can count). Mentions saying the effect did not happen are left out; that check reads keywords, so it can miss some. The shaded band on a bar, and the small range after its number, is the 95% interval: where the share could plausibly be with other reports of the same kind. Fewer reports, wider band. Tap or hover any number for details. The second value is the Bluelight extractor's per-effect confidence; a dash means the row is Erowid-derived, which has no confidence measurement.

    Too few reports for bars: these effects come from 13 single-substance Erowid reports, and a bar is drawn only from 20 reports or more. With fewer, a percentage cannot tell a common effect from a rare one. Counts are shown instead. Why 20?

    Positive Effects 4

    9 of 13 –
    7 of 13 –
    3 of 13 –
    3 of 13 –

    Adverse Effects 5

    6 of 13 –
    4 of 13 –
    3 of 13 –
    3 of 13 –
    3 of 13 –

    Also reported in combinations. In the 4 Methcathinone reports where another drug was taken too, 0 mention hospital, emergency services or an overdose, 1 a seizure and 0 psychosis (too few reports for percentages). In the 13 single-substance reports: 0, 2 and 3. These are not in the figures above: they cannot be put down to Methcathinone alone, and a mention is not always something that happened to the writer.

    Combinations

    Cross-Check Methcathinone with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, Bluelight, and Dose.wiki. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

    Erowid 8 reports 1 positive 2 neutral 5 cautionary visit
    A Wonderful Breakthrough positive exp #66893

    Tonight I may have taken the largest dose of Methcathinone I have ever taken. I must say that I am both surprised and pleased by what I am experiencing. I have taken this drug many times before and have never had the 'breakthrough' type of experience that I am having right now.

    Brain Damage · 280 mg oral
    The Methcathinone Project cautionary exp #1792

    I guess it all started when I heard about a new drug craze that had just been detected in Michigan by the local authorities. I'd say it was somewhere around the middle of 1993.

    Anonymous
    The Not-so-Friendly Kitten cautionary exp #39168

    I hate the name of this drug. Impossible for me to pronounce or spell. Very appropriate. A friend of a distant cousin brewed up a batch of this stuff... about 2 grams of it... and left it under a rock near my mailbox. While shoveling snow, I stumbled upon it and decided to check it out.

    me! · repeated smoked / 10 mg IV / rectal
    Soaring Into the Ground neutral exp #19541

    >Erowid Note: We aren't sure whether the substance described in the following report was methcathinone or cathinone. Last night, a good friend of mine came over. This was the same friend who initially introduced me to harder narcotics.

    bite · 50 mg oral
    Useful neutral exp #33366

    [Erowid Note: This report is marked as a methcathinone report, but readers should be aware there are aspects of it that suggest the identification is speculative.] When I first encountered methcathinone (erroneously called ice by the mentally imperfect oaf (read idiot) who had been using it for at least 6-8 months), I...

    Astral · smoked
    First Trial cautionary exp #38650

    I was not planning on doing any stimulants that night but a chance came up to try Metacthinone. I'm always down to add another substance to my resume and in this case I was interested in the serotogenic action of this particular stimulant and how it compares to meth (the best stimulant period IMHO).

    Smoker2004 · 100 mg oral / 0.075 mg oral
    Robotic Concentration cautionary exp #50221

    General Background: 21 year old male, once an extremely heavy user of psychedelics, particularly research chemicals. Stopped using drugs for a couple of years, after recovering from an opiate/benzodiazepine addiction catalyzed by HPPD/Psychosis (the result of reckless hallucinogen abuse).

    Johnny Yen · repeated insufflated
    Strange Properties cautionary exp #64285

    The synthesis was initially a success, I had at least 1 gram of MCAT freebase. This is where things got a little iffy: In the absence of a suitable base for the substance, I hypothesized that I could slowly evaporate most of the water out, making a concentrated freebase solution.

    Brain Damage
    Bluelight 2 threads 1 positive 1 neutral visit
    Methcathinone Experiensed First Time After Half Yr Break neutral

    back in the days it was legal and i used to take bunches of these capsules half gram each, 10+ capsules. those amounts prodused crack-like high, powerful as 2 E's and lasted good cuple hrs! it can be the thing but u need a lot and after 8 capseles dropped my heart dance next morning so i fuck it off of my life for thet...

    →

    Helpful Links

    Add missing routes to PsychonautWiki Journal

    The PsychonautWiki Journal app already has Methcathinone, but its built-in entry only covers Oral. Here are the other routes we have data for. You can't edit a built-in substance, but you can add a Custom Unit for any of these routes to log it.

    ⬇ Download import file Import this file as custom substances and you get "Methcathinone (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.
    Duration (reference)
    Methcathinone: routes the PsychonautWiki Journal app is missing
    Source: SubstanceSearch (substancesearch.com)
    
    
    Insufflated duration: onset 5-10m ยท come-up 15-30m ยท peak 1-2h ยท offset 1-2h ยท total 2.33-4.67h ยท after-effects 2-6h
    
    Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Ranges are harm-reduction guidance, not a prescription.