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    ๐Ÿงช This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    Methcathinone Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 3 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • 18 combo interactions documented
    • classified Research-chemical

    Aliases: Mc, Cat, Kat, Jeff, M-kat

    Summary dose.wiki PsychonautWiki

    Methcathinone is a Schedule I controlled substance internationally and in the US. Illicit synthesis using potassium permanganate oxidation of ephedrine/pseudoephedrine has been associated with manganese-induced neurotoxicity resembling Parkinson's disease symptoms. Causes severe dehydration and increased perspiration requiring constant hydration to prevent rhabdomyolysis.

    Dose Information dose.wiki PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 50-100mg 100-200mg 200-300mg 300mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects dose.wiki PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 10-30 min 30-60 min 1-2 hrs 1-2 hrs 2-6 hrs 2.67-5.5 hrs
    Insufflated 5-10 min 15-30 min 1-2 hrs 1-2 hrs 2-6 hrs 2.33-4.67 hrs

    Effect Profile

    17 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Empathogen 5.6
    Strong 6/10

    Moderate stimulation and euphoria with mild empathy and sensory enhancement

    Empathy / Social Openness ×3
    5
    empathy enhancement increased sociability
    Euphoria / Mood Elevation ×2
    6
    physical euphoria cognitive euphoria
    Stimulation ×1
    7
    stimulation wakefulness teeth grinding increased heart rate
    Sensory Enhancement ×1
    5
    tactile enhancement increased libido
    Stimulant 5.9
    Strong 6/10

    Strong anxiety/jitters and focus with moderate euphoria, mild stimulation

    Stimulation / Energy ×3
    5
    stimulation wakefulness
    Euphoria / Mood Lift ×2
    7
    physical euphoria cognitive euphoria motivation enhancement
    Focus / Productivity ×2
    9
    focus enhancement analysis enhancement motivation enhancement thought acceleration
    Anxiety / Jitters ×1
    10
    anxiety paranoia increased heart rate teeth grinding vasoconstriction
    Based on reports from:

    Add missing routes to PsychonautWiki Journal

    The PsychonautWiki Journal app already has Methcathinone, but its built-in entry only covers Oral. Here are the other routes we have data for. You can't edit a built-in substance, but you can add a Custom Unit for any of these routes to log it.

    ⬇ Download import file Import this file as custom substances and you get "Methcathinone (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.
    Dose & duration (reference)
    Methcathinone: routes the PsychonautWiki Journal app is missing
    Source: SubstanceSearch (substancesearch.com)
    
    Insufflated dose (mg): threshold 5-10
    
    Insufflated duration: onset 5-10m ยท come-up 15-30m ยท peak 1-2h ยท offset 1-2h ยท total 2.33-4.67h ยท after-effects 2-6h
    
    Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Custom Units carry a single dose per route, so the full ranges live in the reference above. A route's suggested dose is the midpoint of its common range. Ranges are harm-reduction guidance, not a prescription.

    Tolerance

    Build-up develops rapidly, often within a single session; compulsive redosing common
    Reset a few days for acute tolerance

    Tolerance Decay

    Full tolerance 2d Half tolerance 4d Baseline ~10d

    Rapid tolerance is commonly reported with repeated use over days; rough decay to baseline over ~1โ€“2 weeks is inferred from community reports and stimulant analogues. Data quality is limited and interindividual variability is high.

    Cross-Tolerances

    Effects Erowid

    Aggregated from 17 Erowid experience reports

    Positive Effects 4

    Stimulation 82.4% 70%
    Euphoria 58.8% 70%
    Focus Enhancement 35.3% 70%
    Empathy 17.6% 70%

    Adverse Effects 8

    Anxiety 47.1% 70%
    Confusion 29.4% 70%
    Seizure 17.6% 70%
    Psychosis 17.6% 70%
    Pupil Dilation 17.6% 70%
    Nausea 17.6% 70%
    Muscle Tension 17.6% 70%
    Headache 17.6% 70%

    Combinations

    Cross-Check Methcathinone with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

    Erowid 8 reports 3 neutral 5 cautionary visit
    A Wonderful Breakthrough neutral exp #66893

    Tonight I may have taken the largest dose of Methcathinone I have ever taken. I must say that I am both surprised and pleased by what I am experiencing. I have taken this drug many times before and have never had the 'breakthrough' type of experience that I am having right now.

    Brain Damage · 280 mg oral
    The Methcathinone Project cautionary exp #1792

    I guess it all started when I heard about a new drug craze that had just been detected in Michigan by the local authorities. I'd say it was somewhere around the middle of 1993.

    Anonymous
    The Not-so-Friendly Kitten cautionary exp #39168

    I hate the name of this drug. Impossible for me to pronounce or spell. Very appropriate. A friend of a distant cousin brewed up a batch of this stuff... about 2 grams of it... and left it under a rock near my mailbox. While shoveling snow, I stumbled upon it and decided to check it out.

    me! · repeated smoked / 10 mg IV / rectal
    Soaring Into the Ground neutral exp #19541

    >Erowid Note: We aren't sure whether the substance described in the following report was methcathinone or cathinone. Last night, a good friend of mine came over. This was the same friend who initially introduced me to harder narcotics.

    bite · 50 mg oral
    Useful neutral exp #33366

    [Erowid Note: This report is marked as a methcathinone report, but readers should be aware there are aspects of it that suggest the identification is speculative.] When I first encountered methcathinone (erroneously called ice by the mentally imperfect oaf (read idiot) who had been using it for at least 6-8 months), I...

    Astral · smoked
    First Trial cautionary exp #38650

    I was not planning on doing any stimulants that night but a chance came up to try Metacthinone. I'm always down to add another substance to my resume and in this case I was interested in the serotogenic action of this particular stimulant and how it compares to meth (the best stimulant period IMHO).

    Smoker2004 · 100 mg oral / 0.075 mg oral
    Robotic Concentration cautionary exp #50221

    General Background: 21 year old male, once an extremely heavy user of psychedelics, particularly research chemicals. Stopped using drugs for a couple of years, after recovering from an opiate/benzodiazepine addiction catalyzed by HPPD/Psychosis (the result of reckless hallucinogen abuse).

    Johnny Yen · repeated insufflated
    Strange Properties cautionary exp #64285

    The synthesis was initially a success, I had at least 1 gram of MCAT freebase. This is where things got a little iffy: In the absence of a suitable base for the substance, I hypothesized that I could slowly evaporate most of the water out, making a concentrated freebase solution.

    Brain Damage
    Bluelight 5 threads 5 neutral visit
    N Cat Trip Report From A New User neutral

    Hi, new here, but a long time reader. Since the Meph ban me and my wife have been looking for something legal to take to have pleasant evenings in together, since with 2 kids, we're usually pretty shattered in the evenings, and we rarely get time together, so a little something to keep us awake and having fun all night...

    scraped 2026-03-14
    Methcathinone Hydrochloride Experienced Cat Trip Report And Summary neutral

    Hey, hi. I don't often write on Bluelight, but I read a lot . To fill you in: I've eaten and snorted my way through an alphabet soup over the years, like many of you. And, of allll the various molecules, I tend to prefer stimulants that are euphoric.

    scraped 2026-03-14
    Mdxa First Time Is That A Cat On Her Head neutral

    Ecstasy - first time - IS THAT A CAT ON HER HEAD? I finally catch up with my bro and i drop my first half, now remember this is my first drop, and man all mighty this thing tastes like SHIT!!!! it smelt like a gone off smoker candy, it was called "pink dollars"., it also tasted like a gone off smoker candy, none the le...

    scraped 2026-03-14
    Motion Sickness Pills 4 My Cat Can Talk neutral

    motion sickness pills my cat can talk It starts when i was 17 and my lsd supply ran off somewhere, to this day i don't know what happened to him but he just flat out disappeared from my world.

    scraped 2026-03-14
    Methcathinone Experiensed First Time After Half Yr Break neutral

    back in the days it was legal and i used to take bunches of these capsules half gram each, 10+ capsules. those amounts prodused crack-like high, powerful as 2 E's and lasted good cuple hrs! it can be the thing but u need a lot and after 8 capseles dropped my heart dance next morning so i fuck it off of my life for thet...

    scraped 2026-03-14

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