Methyprylon
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 1 source
- 1 ROA with full dose ladder
- duration data present
- 17 combo interactions documented
- PubChem toxicity data
- classified Tentative
- 1 source
- 1 ROA with full dose ladder
- duration data present
- 17 combo interactions documented
- PubChem toxicity data
- classified Tentative
Aliases: Noludar
Summary
Sedative of the pipeidinedone family. Was used for treating insomnia, yet is rarely used today due to substances with fewer side effects, such as benzodiazepines.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 150-200mg | 200-300mg | 300mg+ | - |
Onset, Duration & After-effects
| ROA | Peak | Total |
|---|---|---|
| Oral | 6-12 hrs | 6-12 hrs |
Effect Profile
class estimateScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- No reports exist for this substance. Its effect list is the one shared by 1 other substance of the same class, so the scores below describe the class, not this compound.
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong euphoria with low anxiolysis, sedation, and cognitive impairment
Add to PsychonautWiki Journal
The PsychonautWiki Journal logging app doesn't include every substance. To track Methyprylon there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:
Methyprylon Source: SubstanceSearch (substancesearch.com) Oral dose (mg): light 150-200 · common 200-300 · strong 300+ Oral duration: peak 6-12h · total 6-12h · after-effects 1-16h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 250 mg (Oral).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
- Stimulation
- Motor impairment
- Increased heart rate
- Pupil dilation
- Insomnia
- Nausea
- Vasoconstriction
- Restlessness
- Sedation
- Decreased appetite
- Reduced anxiety
- Euphoria
- Cognitive euphoria
- Wakefulness
- Empathy
- Anxiety
- Confusion
- Compulsive redosing
- Time distortion
- Talkativeness
- Increased music appreciation
- Color enhancement
- Tactile enhancement
- Brightened colour
- Light sensitivity
- Appetite suppression
- Dehydration
- Disinhibition
- Dulled perception
- Drifting
Combinations
Cross-Check Methyprylon with another substanceHelpful Links
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