Methyprylon
Aliases: Noludar
Summary
Sedative of the pipeidinedone family. Was used for treating insomnia, yet is rarely used today due to substances with fewer side effects, such as benzodiazepines.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 150-200mg | 200-300mg | 300mg | 300mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Benzodiazepine
4.7
Moderate+
5/10
Strong euphoria with low anxiolysis, sedation, and cognitive impairment
Anxiolysis
×3
3
reduced anxiety
Sedation / Relaxation
×2
3
sedation
Motor / Cognitive Impairment
×1
2
confusion
Euphoria / Mood Lift
×1
10
euphoria
cognitive euphoria
disinhibition
Based on reports from:
Tolerance
Build-up
develops over 1–4 weeks of daily use; hypnotic tolerance faster than anxiolytic tolerance
Reset
weeks to months depending on half-life and duration of use; taper recommended
Tolerance Decay
Full tolerance
3d
Half tolerance
37d
Baseline
~60d
Effects
Positive
- Stimulation
Negative
- Motor impairment
- Increased heart rate
- Pupil dilation
- Insomnia
- Nausea
- Vasoconstriction
- Restlessness
- Sedation
- Decreased appetite
Positive
- Reduced anxiety
- Euphoria
- Cognitive euphoria
- Wakefulness
- Empathy
Negative
- Anxiety
- Confusion
- Compulsive redosing
- Time distortion
- Talkativeness
Positive
- Increased music appreciation
- Color enhancement
- Tactile enhancement
- Brightened colour
Negative
- Light sensitivity
- Appetite suppression
- Dehydration
- Disinhibition
- Dulled perception
- Drifting
Combinations
Methyprylon's nerd page
Pharmacology, chemical data, effect profiles, and more
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