Metizolam
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 4 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 17 combo interactions documented
- toxicity data (PsychonautWiki)
- classified Tentative
- classified Research-chemical
- 4 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 17 combo interactions documented
- toxicity data (PsychonautWiki)
- classified Tentative
- classified Research-chemical
Aliases: Metiz, Desmethyletizolam
Summary
Metizolam is a research chemical with very little history of human use and minimal scientific study. It was patented in 1995 but never marketed as a medication. Due to its extreme potency, volumetric liquid dosing is strongly recommended to ensure accurate administration.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 1-2mg | 2-4mg | 4-6mg | 6mg+ |
Onset, Duration & After-effects
| ROA | Onset | Peak | Offset | Total |
|---|---|---|---|---|
| Oral | 30-90 min | 30 min | 3-6 hrs | 5-8 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong anxiolysis and euphoria with moderate cognitive impairment, mild sedation
Import into PsychonautWiki Journal
The PsychonautWiki Journal app includes Metizolam, but its built-in data can be thinner than ours. Importing this file adds a separate "Metizolam (Substance Search)" custom substance with our dose ranges, durations and tolerance, so you can log against whichever you prefer.
Ranges are harm-reduction guidance, not a prescription.
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
- Muscle Relaxation
- Physical euphoria
- Anxiolytic
- Respiratory Depression
- Motor impairment
- Sedation
- Sedative
- Dystaxia
- Anxiety Suppression
- Dream Potentiation
- Cognitive Euphoria
- Motor Control Loss
- Amnesia
- Dizziness
- Thought Deceleration
- Emotion Suppression
- Delusions of Sobriety
- Compulsive Redosing
- Analysis Suppression
- Delusions
- Information processing suppression
- Increased libido
- Appetite enhancement
- Increased music appreciation
- Disinhibition
- Visual acuity suppression
- Acuity suppression
- Dehydration
- Light sensitivity
- Dulled perception
- Perception of bodily heaviness
Combinations
Cross-Check Metizolam with another substanceHelpful Links
Report an issue or suggest an edit
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