Mexazolam
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 1 source
- 1 ROA with full dose ladder
- duration data present
- 17 combo interactions documented
- PubChem toxicity data
- 1 source
- 1 ROA with full dose ladder
- duration data present
- 17 combo interactions documented
- PubChem toxicity data
Aliases: Melex, Sedoxil
Summary
Benzodiazepine derivative that has been trialed for anxiety and was found to be effective for anxiety at one week week follow-ups yet after three weeks it had lost its therapeutic anxiolytic properties and becoming no more effective than placebo.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 0.25-0.5mg | 0.5-1.5mg | 1.5-2mg | 2-3mg+ |
Onset, Duration & After-effects
| ROA | Onset | Peak | Total |
|---|---|---|---|
| Oral | 5-45 min | 4-8 hrs | 4-8 hrs |
Effect Profile
class estimateScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- No reports exist for this substance. Its effect list is the one shared by 1 other substance of the same class, so the scores below describe the class, not this compound.
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong euphoria and anxiolysis with mild sedation, low cognitive impairment
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The PsychonautWiki Journal logging app doesn't include every substance. To track Mexazolam there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:
Mexazolam Source: SubstanceSearch (substancesearch.com) Oral dose (mg): light 0.25-0.5 · common 0.5-1.5 · strong 1.5-2 · heavy 2-3+ Oral duration: onset 5-45m · peak 4-8h · total 4-8h · after-effects 1-12h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 1 mg (Oral).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
- Stimulation
- Physical euphoria
- Muscle relaxation
- Motor impairment
- Increased heart rate
- Nausea
- Vasoconstriction
- Respiratory depression
- Teeth grinding
- Sedation
- Reduced anxiety
- Cognitive euphoria
- Euphoria
- Anxiety suppression
- Wakefulness
- Anxiety
- Compulsive redosing
- Dizziness
- Thought deceleration
- Time distortion
- Increased music appreciation
- Increased libido
- Tactile enhancement
- Color enhancement
- Disinhibition
- Appetite suppression
- Dehydration
- Light sensitivity
- Double vision
- Dulled perception
Combinations
Cross-Check Mexazolam with another substanceHelpful Links
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