Mexedrone
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 4 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 18 combo interactions documented
- PubChem toxicity data
- classified Tentative
- classified Research-chemical
- 4 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 18 combo interactions documented
- PubChem toxicity data
- classified Tentative
- classified Research-chemical
Aliases: 4-mmeoc, 4-mmc-meo
Summary
Mexedrone is a research chemical with very little history of human use prior to 2015. It was marketed as a legal alternative to mephedrone but is reported to be approximately 10-20 times weaker in potency, requiring higher doses to achieve comparable effects. The substance has been associated with significant sedation rather than stimulation, distinguishing it from mephedrone.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 100-150mg | 150-250mg | 250-350mg | 350mg+ |
| Insufflated | 50-80mg | 80-120mg | 120-200mg | 200mg+ |
Onset, Duration & After-effects
| ROA | Onset | Peak | Offset | Total |
|---|---|---|---|---|
| Oral | 30-60 min | 2-3 hrs | 1-2 hrs | 4-6 hrs |
| Insufflated | 5-20 min | 1.5-2.5 hrs | 1-2 hrs | 1-3 hrs |
Effect Profile
1 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong sensory enhancement and euphoria with moderate stimulation
Strong euphoria and anxiety/jitters with mild stimulation, low focus
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
- Physical Euphoria
- Spontaneous tactile sensations
- Stimulation
- Increased Perspiration
- Temperature Regulation Suppression
- Teeth Grinding
- Nystagmus
- Increased heart rate
- Pupil dilation
- Sedation
- Euphoria
- Thought Connectivity
- Cognitive euphoria
- Wakefulness
- Anxiety
- Cognitive Fatigue
- Depression
- Irritability
- Thought Acceleration
- Thought acceleration
- Tactile Enhancement
- Auditory Enhancement
- Increased music appreciation
- Tactile enhancement
- Increased libido
- Tracers
- Dehydration
- Appetite suppression
- Spontaneous Physical Sensations
- Vibrating vision
Combinations
Cross-Check Mexedrone with another substanceHelpful Links
Report an issue or suggest an edit
Spotted incorrect or dangerous information, have a correction, a new study, or a useful addition for Mexedrone? Let us know. Reports are reviewed by moderators — this is not posted publicly.