Mexedrone Stats & Data
CC1=CC=C(C=C1)C(=O)C(COC)NCJHGDCSPZKQLBOP-UHFFFAOYSA-NInteraction Warnings
This combination may increase strain on the heart.
Receptor Profile
Receptor Actions
Subjective Effects
Physical
- Physical euphoria
- Tactile enhancement
- Sedation: The biggest difference between mexedrone and mephedrone is that it primarily results in moderate sedation over stimulation and can therefore discourage physical activities such as running, dancing or climbing.
- Spontaneous tactile sensations: The "body high" of mexedrone can be described as a mild soft and warm tingling sensation that encompasses the entire body. This sensation maintains a consistent presence that steadily rises with the onset and hits its limit once the peak has been reached.
- Dehydration
- Vibrating vision: At high doses, a person's eyeballs may begin to spontaneously wiggle back and forth in a rapid motion, causing the vision to become blurry and temporarily out of focus. This is a condition known as nystagmus.
- Increased perspiration
- Temperature regulation suppression
- Teeth grinding: This component can be considered to be less intense when compared with that of MDMA.
Cognitive
- Euphoria: Mild emotional euphoria and feelings of happiness are present within mexedrone and are likely a direct result of serotonin and dopamine release.
- Thought acceleration
- Thought connectivity
Sensory
- Enhancements
Forked from Subjective Effect Documentation work by Josie Kins, August 2016. Via dose.wiki (CC0).
Toxicity
PsychonautWikiThe toxicity and long-term health effects of recreational mexedrone use do not seem to have been studied in any scientific context and the exact toxic dosage is unknown. This is because mexedrone has very little history of human usage. Anecdotal reports from those who have tried mexedrone within the community suggest that there do not seem to be any negative health effects attributed to simply trying this drug at low to moderate doses by itself and using it sparingly (but nothing can be completely guaranteed). It is strongly recommended that one use harm reduction practices when using this drug.
Effect Profile
Curated + 1 ReportsStrong euphoria and sensory enhancement with moderate stimulation
Strong euphoria and anxiety/jitters with mild stimulation, low focus
Tolerance & Pharmacokinetics
drugs.wikiTolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Experience Report Analysis
ErowidDemographics
Gender Distribution
Age Distribution
Reports Over Time
Real-World Dose Distribution
62K DosesFrom 1 individual dose entries
Legal Status
| Country | Status | Notes |
|---|---|---|
| Sweden | Mexedrone is illegal | |
| Switzerland | Mexedrone is a controlled substance specifically named under Verzeichnis E. |
References
Data Sources
Cited References
- Bluelight: Mexedrone Discussion Thread
- McLaughlin et al. (2017) - Synthesis, characterization and monoamine transporter activity of mexedrone
- Roberts et al. (2017) - 11 analytically confirmed cases of mexedrone use among polydrug users
- WEDINOS Mexedrone Sample Analysis
- McLaughlin et al. (2017) - Synthesis, characterization and monoamine transporter activity of mexedrone