methoxMETAmine Set: Heartbroken and depressed as hell and feeling reckless for no real reason, it was the first day of school and I just had this capsule and I wanted to dis out that night because I had a late class the next day.
MXM
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 3 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 18 combo interactions documented
- classified Research-chemical
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 3 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 18 combo interactions documented
- classified Research-chemical
Aliases: Mmxe, Methoxmetamine, 3-meo-2'-oxo-pcm
Summary
MXM (3-MeO-2'-Oxo-PCM) is the N-methyl homologue of methoxetamine; replacing the ethyl with a methyl lowers potency roughly 2- to 3-fold but shortens the high to about three hours. Forum experiments suggest oral administration is far more efficient than insufflation, likely due to low nasal absorption; 50-75 mg oral produces warm, serene dissociation and mild empathogenic warmth, while the same amount intranasally may do little. Users describe a 'ketamine-lite' float with MXE-style emotional openness, but with faster tolerance and heavier compulsion to redose.
Perspectives
“MXM is an ample substitute for MXE in my opinion. It has slightly shorter duration and the experience itself lacks the inherent euphoria and giddiness, but has that same sense of whimsy, adventure, and motion, and is substantially powerful.”
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral / Sublingual | 20-40mg | 40-60mg | 60-100mg | 100mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral / Sublingual | 30-45 min | 15-30 min | 30-90 min | 1-2 hrs | 3-5 hrs |
| Insufflated | 4-15 min | 10-19 min | 30-90 min | 1-2 hrs | 3-5 hrs |
| Intramuscular | 1-4 min | 4-15 min | 30-90 min | 1-2 hrs | 3-5 hrs |
| Rectal | 10-19 min | 15-30 min | 30-90 min | 1-2 hrs | 3-5 hrs |
Effect Profile
1 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Dissociative
6.0
Strong
6/10
Strong dissociative depth and motor impairment with mild mania, low insight
Dissociative Depth
×3
10
depersonalization
derealization
physical disconnection
cognitive disconnection
visual disconnection
spatial disorientation
+2 more
Mania / Compulsion
×1
4
disinhibition
stimulation
Insight / Novel Thought
×2
3
conceptual thinking
Motor / Sensory Impairment
×1
10
motor control loss
physical disconnection
tactile suppression
numbness
spatial disorientation
visual disconnection
+1 more
Based on reports from:
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Name
MXM
Unit
mg
Description
MXM Source: SubstanceSearch (substancesearch.com) Oral / Sublingual dose (mg): threshold 15 · light 20-40 · common 40-60 · strong 60-100 · heavy 100+ Insufflated dose (mg): threshold 20 Intramuscular dose (mg): threshold 5 Rectal dose (mg): threshold 10 Oral / Sublingual duration: onset 30-45m · come-up 15-30m · peak 0.5-1.5h · offset 1-2h · total 3-5h · after-effects 1-12h Insufflated duration: onset 4-15m · come-up 10-19m · peak 0.5-1.5h · offset 1-2h · total 3-5h · after-effects 1-12h Intramuscular duration: onset 1-4m · come-up 4-15m · peak 0.5-1.5h · offset 1-2h · total 3-5h · after-effects 1-12h Rectal duration: onset 10-19m · come-up 15-30m · peak 0.5-1.5h · offset 1-2h · total 3-5h · after-effects 1-12h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 50 mg (Oral / Sublingual).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Build-up
develops with repeated use over days to weeks
Reset
2–4 weeks for noticeable reduction
Tolerance Decay
Half tolerance
14d
Baseline
~28d
Tolerance appears to increase rapidly after one strong session and decays over 1–2+ weeks, consistent with other arylcyclohexylamines; values are heuristic from user reports, not formal studies.
Cross-Tolerances
Effects
Positive
- Physical euphoria
- Stimulation
- Pain relief
- Analgesia
Negative
- Numbness
- Loss of balance
- Nausea
- Increased heart rate
- Physical disconnection
- Sedation
Positive
- Cognitive euphoria
- Conceptual thinking
Negative
- Depersonalization
- Derealization
- Motor control loss
- Anxiety
- Amnesia
- Memory suppression
- Cognitive disconnection
- Time distortion
Positive
- Increased music appreciation
- Tactile enhancement
Negative
- Derealization
- Disinhibition
- Tactile suppression
- Spatial disorientation
- Double vision
- Pattern recognition suppression
- Visual disconnection
- Auditory distortion
Combinations
Cross-Check MXM with another substanceTrip Reports
Community Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.
Erowid 1 report 1 positive visit
Bluelight 2 threads 2 neutral visit
(please note this is methox M etamine, aka MXM, not MXE) Dose: 70 mg ROA: Sublingual Set: Heartbroken and depressed as hell and feeling reckless for no real reason, it was the first day of school and I just had this capsule and I wanted to dis out that night because I had a late class the next day.
Held 70mg MXM under the tongue for about 5 minutes before swallowing. Start to feel good at T+40m. All of a sudden, I find myself more talkative. My wife knows that the experiment is on, but she herself is pregnant, so she hasn't partaken. Nevertheless, she finds herself with a contact high right away.
Bluelight Reference Guide
☛ Official ☚ The Big & Dandy Methoxmetamine / MXM Thread
(RS)2-(3-methoxyphenyl)-2-(methylamino)cyclohexanone Or 3-MeO-2'-OxO-PCM, while MXE is 3-MeO-2'-Oxo-PCE. Seems to slowly become available. Makes sense, with the EU ban on MXE. Expectations and experience reports welcome Mod note: Please be aware that this has been sold as E-MXE or E-methoxetamine.
Read full thread on Bluelight →
MXM's nerd page
Pharmacology, chemical data, effect profiles, and more
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Helpful Links
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