MXM
Aliases: Mmxe, Methoxmetamine, 3-meo-2'-oxo-pcm
Summary
MXM (3-MeO-2'-Oxo-PCM) is the N-methyl homologue of methoxetamine; replacing the ethyl with a methyl lowers potency roughly 2- to 3-fold but shortens the high to about three hours. Forum experiments suggest oral administration is far more efficient than insufflation, likely due to low nasal absorption; 50-75 mg oral produces warm, serene dissociation and mild empathogenic warmth, while the same amount intranasally may do little. Users describe a 'ketamine-lite' float with MXE-style emotional openness, but with faster tolerance and heavier compulsion to redose.
Perspectives
“MXM is an ample substitute for MXE in my opinion. It has slightly shorter duration and the experience itself lacks the inherent euphoria and giddiness, but has that same sense of whimsy, adventure, and motion, and is substantially powerful.”
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral / Sublingual | 20-40mg | 40-60mg | 60-100mg | 100mg+ |
| Oral | 20-40mg | 40-60mg | 60-100mg | 100mg+ |
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral / Sublingual | 30-45 min | 15-30 min | 30-90 min | 1-2 hrs | 3-5 hrs |
| Insufflated | 4-15 min | 10-19 min | 30-90 min | 1-2 hrs | 3-5 hrs |
| Intramuscular | 1-4 min | 4-15 min | 30-90 min | 1-2 hrs | 3-5 hrs |
| Rectal | 10-19 min | 15-30 min | 30-90 min | 1-2 hrs | 3-5 hrs |
Effect Profile
1 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong dissociative depth and motor impairment with mild mania, low insight
Tolerance
Tolerance Decay
Tolerance appears to increase rapidly after one strong session and decays over 1–2+ weeks, consistent with other arylcyclohexylamines; values are heuristic from user reports, not formal studies.
Cross-Tolerances
Effects
- Physical euphoria
- Stimulation
- Pain relief
- Analgesia
- Numbness
- Loss of balance
- Nausea
- Increased heart rate
- Physical disconnection
- Sedation
- Cognitive euphoria
- Conceptual thinking
- Depersonalization
- Derealization
- Motor control loss
- Anxiety
- Amnesia
- Memory suppression
- Cognitive disconnection
- Time distortion
- Increased music appreciation
- Tactile enhancement
- Derealization
- Disinhibition
- Tactile suppression
- Spatial disorientation
- Double vision
- Pattern recognition suppression
- Visual disconnection
- Auditory distortion