N-Methyl-Cyclazodone
Aliases: Nmc, Ld 4202
Summary
N-Methyl-Cyclazodone is approximately 4-6 times more potent than its parent compound cyclazodone. Human pharmacological data are extremely limited; structurally related pemoline analogs have documented hepatotoxicity, warranting caution with chronic use. A 2022 case report documented severe toxicity requiring hospitalization after ~5g cumulative intake over 5 days.
Dose Information
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset |
|---|---|---|---|---|
| Oral | 15-45 min | 30-60 min | 2-5 hrs | 2-3 hrs |
| Sublingual | 10-30 min | 20-45 min | 2-5 hrs | 2-3 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong anxiety/jitters with moderate stimulation and euphoria, mild focus
Tolerance
Tolerance Decay
Estimates above reflect community patterns for stimulant tolerance accrual and decay and the similarity between NMC and cyclazodone; no human pharmacology studies define exact rates. Frequent use (>2x/week) appears to blunt mood/drive and increase side effects. Data quality: anecdotal.
Cross-Tolerances
Effects
- Stimulation
- Physical euphoria
- Stamina enhancement
- Increased heart rate
- Pupil dilation
- Vasoconstriction
- Increased blood pressure
- Nausea
- Teeth grinding
- Sweating
- Insomnia
- Brightness alteration
- Focus enhancement
- Wakefulness
- Motivation enhancement
- Cognitive euphoria
- Empathy enhancement
- Sociability enhancement
- Verbal fluency enhancement
- Anxiety
- Compulsive redosing
- Time distortion
- Increased music appreciation
- Bodily control enhancement
- Increased libido
- Increased Music Appreciation
- Color enhancement
- Appetite suppression
- Light sensitivity
- Dehydration
- Appetite Suppression
- Dulled perception