Summary
N-Methyl-Cyclazodone is approximately 4-6 times more potent than its parent compound cyclazodone. Human pharmacological data are extremely limited; structurally related pemoline analogs have documented hepatotoxicity, warranting caution with chronic use. A 2022 case report documented severe toxicity requiring hospitalization after ~5g cumulative intake over 5 days. Prolonged wakefulness can obscure sleep debt and appetite suppression may lead to nutritional deficiencies. As a novel research chemical with minimal safety data, periodic liver enzyme monitoring and conservative dosing are strongly advised.
Dose Information
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects |
|---|---|---|---|---|---|
| Oral | 15-45 min | 30-60 min | 2-5 hrs | 2-3 hrs | 3-6 hrs |
| Sublingual | 10-30 min | 20-45 min | 2-5 hrs | 2-3 hrs | 3-6 hrs |
Tolerance
Build-up
develops over days to weeks of regular use
Reset
3–7 days for acute; 1–3 weeks for full reset
Effects
Positive
- Stimulation
- Physical euphoria
- Stamina enhancement
Negative
- Increased heart rate
- Pupil dilation
- Vasoconstriction
- Increased blood pressure
- Nausea
- Teeth grinding
- Sweating
- Insomnia
- Brightness alteration
Positive
- Focus enhancement
- Wakefulness
- Motivation enhancement
- Cognitive euphoria
- Empathy enhancement
- Sociability enhancement
- Verbal fluency enhancement
Negative
- Anxiety
- Compulsive redosing
- Time distortion
Positive
- Increased music appreciation
- Bodily control enhancement
- Increased libido
- Increased Music Appreciation
- Color enhancement
Negative
- Appetite suppression
- Light sensitivity
- Dehydration
- Appetite Suppression
- Dulled perception