Cyclazodone
Aliases: Cyclazadone, Cyclopropylpemoline
Categories
Summary
Cyclazodone is a centrally acting stimulant developed in the 1960s, structurally related to pemoline and 4-methylaminorex. It appeared on the research chemical market in 2017 with limited pharmacological data. While animal studies suggest lower cardiotoxicity and hepatotoxicity than amphetamine, the structurally related pemoline was withdrawn due to causing liver damage in children. Heavy or sustained usage may result in liver damage. Use accurate scales, start with low doses, and employ harm reduction practices.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 5-15mg | 15-25mg | 25-60mg | 60mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects |
|---|---|---|---|---|---|
| Oral | 20-45 min | 30-60 min | 2-4 hrs | 1-2 hrs | 1-6 hrs |
Tolerance
Build-up
develops over days to weeks of regular use
Reset
3–7 days for acute tolerance; longer for full reset
Effects
Positive
- Stimulation
- Physical euphoria
- Stamina enhancement
Negative
- Increased heart rate
- Vasoconstriction
- Pupil dilation
- Increased blood pressure
- Nausea
- Teeth grinding
- Sweating
Positive
- Focus enhancement
- Motivation enhancement
- Wakefulness
- Cognitive euphoria
- Analysis enhancement
- Empathy enhancement
- Euphoria
Negative
- Anxiety
- Thought acceleration
- Time distortion
Positive
- Bodily control enhancement
- Increased libido
- Increased music appreciation
- Increased Music Appreciation
- Color enhancement
Negative
- Appetite suppression
- Light sensitivity
- Dehydration
- Appetite Suppression
- Dulled perception