I got an 8mg Suboxone strip from a friend. I read a few reports of people that had done Suboxone, the very few that I could find that were for recreational use and not to treat withdrawal, and they were all about how sick everyone got.
Naloxone
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 1 source
- 1 ROA with full dose ladder
- duration data present
- 19 combo interactions documented
- PubChem toxicity data
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 1 source
- 1 ROA with full dose ladder
- duration data present
- 19 combo interactions documented
- PubChem toxicity data
Summary
Naloxone (commonly sold under the brand names Narcan and Evzio) is a synthetic mu-opioid antagonist of the morphinan chemical class that is widely used to reverse the effects of an acute opioid overdose. Naloxone is sold under the brand name Narcan as a nasal spray and Evzio as an auto-injector with voice instructions.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Insufflated | - | 1-4mg | - | - |
| Intramuscular | - | 0.4-2mg | - | - |
| Intravenous | - | 0.4-2mg | - | - |
| Oral | 4-8mg | 8-16mg | 16-28mg | 28mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Insufflated | 0-10 min | - | - | - | 30-60 min |
| Intramuscular | 0-2 min | - | - | - | 30-60 min |
| Intravenous | 0-2 min | - | - | - | 30-60 min |
| Oral | 6-12 min | 18-42 min | 1-2 hrs | 30-60 min | - |
Effect Profile
46 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Validated against 46 Erowid trip reports
- Weighted by importance: core (×3), major (×2), minor (×1)
Opioid
6.6
Strong+
7/10
Strong euphoria, itching/nausea, and sedation with mild pain relief
Euphoria / Warmth
×3
10
physical euphoria
euphoria
cognitive euphoria
mood lift
Analgesia
×2
4
analgesia
Sedation / Relaxation
×1
8
sedation
dream potentiation
Itching / Nausea
×1
10
nausea
constipation
dry mouth
Based on reports from:
Tolerance
Build-up
develops within days of regular use; analgesic tolerance faster than respiratory depression tolerance
Reset
7–14 days for partial reset; full reset may take weeks — tolerance loss greatly increases overdose risk
Tolerance Decay
Full tolerance
1d
Half tolerance
21d
Baseline
~35d
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
Aggregated from 46 Erowid experience reports
Positive Effects 10
Sedation
30.4%
70%
Anxiety Suppression
30.4%
70%
Euphoria
28.3%
70%
Empathy
26.1%
70%
Stimulation
26.1%
70%
Tactile Enhancement
10.9%
70%
Focus Enhancement
6.5%
70%
Color Enhancement
6.5%
70%
Music Enhancement
6.5%
70%
Body High
6.5%
70%
Adverse Effects 5
Nausea
19.6%
70%
Confusion
17.4%
70%
Headache
17.4%
70%
Increased Heart Rate
8.7%
70%
Sweating
6.5%
70%
Combinations
Cross-Check Naloxone with another substanceCommunity Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.
Erowid 2 reports 1 neutral 1 cautionary visit
[Erowid Note: Intravenous (IV) injection of crushed pills/tablets can be very dangerous due to unknown substances, binders, and fillers present. Any substance injected directly into the blood stream should be very pure.
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