Pagoclone
Limited data
Limited data
Sparse data. Doses and effects may be unreliable or untested.
- 2 corroborating sources
- partial dose data
- classified Tentative
- classified Research-chemical
- 2 corroborating sources
- partial dose data
- classified Tentative
- classified Research-chemical
Summary
Pagoclone is a non-benzodiazepine anxiolytic of the cyclopyrrolone class., While it is closely related to "Z-drugs" (like zolpidem and zopiclone), pagoclone is unique in that it does not produce sedation or as much loss of motor control and amnesia that benzodiazepines and other Z-drugs do. As with many z-drugs, it is reported to cause hallucinations similar to deliriants, albeit with much less pronounced effects. Pagoclone has been considered by David Nutt, in his search for alcohol alternatives, as a useful base from which to derive viable alternatives.
Dose Information
No curated dose ladder is available for this substance. The figures below are drawn from SubstanceIndex (DoseWiki) as a fallback — often a conservative threshold only. Treat them as approximate and cross-reference before use.
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | - | 0.3-0.6mg/day | - | - |
Add to PsychonautWiki Journal
The PsychonautWiki Journal logging app doesn't include every substance. To track Pagoclone there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:
Pagoclone Source: SubstanceSearch (substancesearch.com) Oral dose (mg/day): common 0.3-0.6 Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 0.45 mg/day (Oral).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
- Stimulation
- Motor impairment
- Increased heart rate
- Pupil dilation
- Insomnia
- Nausea
- Vasoconstriction
- Restlessness
- Sedation
- Decreased appetite
- Reduced anxiety
- Euphoria
- Cognitive euphoria
- Wakefulness
- Empathy
- Anxiety
- Confusion
- Compulsive redosing
- Time distortion
- Talkativeness
- Increased music appreciation
- Color enhancement
- Tactile enhancement
- Brightened colour
- Light sensitivity
- Appetite suppression
- Dehydration
- Disinhibition
- Dulled perception
- Drifting
Helpful Links
Report an issue or suggest an edit
Spotted incorrect or dangerous information, have a correction, a new study, or a useful addition for Pagoclone? Let us know. Reports are reviewed by moderators — this is not posted publicly.