Pagoclone
Limited data
Limited data
Sparse data. Doses and effects may be unreliable or untested.
- 2 corroborating sources
- partial dose data
- classified Tentative
- classified Research-chemical
- 2 corroborating sources
- partial dose data
- classified Tentative
- classified Research-chemical
Summary
Pagoclone is a non-benzodiazepine anxiolytic of the cyclopyrrolone class., While it is closely related to "Z-drugs" (like zolpidem and zopiclone), pagoclone is unique in that it does not produce sedation or as much loss of motor control and amnesia that benzodiazepines and other Z-drugs do. As with many z-drugs, it is reported to cause hallucinations similar to deliriants, albeit with much less pronounced effects. Pagoclone has been considered by David Nutt, in his search for alcohol alternatives, as a useful base from which to derive viable alternatives.
Dose Information
No curated dose ladder is available for this substance. The figures below are drawn from SubstanceIndex (DoseWiki) as a fallback — often a conservative threshold only. Treat them as approximate and cross-reference before use.
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | - | 0.3-0.6mg/day | - | - |
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
- Stimulation
- Motor impairment
- Increased heart rate
- Pupil dilation
- Insomnia
- Nausea
- Vasoconstriction
- Restlessness
- Sedation
- Decreased appetite
- Reduced anxiety
- Euphoria
- Cognitive euphoria
- Wakefulness
- Empathy
- Anxiety
- Confusion
- Compulsive redosing
- Time distortion
- Talkativeness
- Increased music appreciation
- Color enhancement
- Tactile enhancement
- Brightened colour
- Light sensitivity
- Appetite suppression
- Dehydration
- Disinhibition
- Dulled perception
- Drifting
Helpful Links
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