Home
    Disclaimer
    πŸ§ͺ This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    Pentedrone Well-documented
    Well-documented
    Multiple authoritative sources agree on dosing and effects.
    • 2 corroborating sources
    • 3 ROAs with full dose ladders
    • duration data present
    • 18 combo interactions documented
    • toxicity data (PsychonautWiki)
    • classified Research-chemical

    Summary PsychonautWiki

    Pentedrone (also known as drone) is a lesser-known novel stimulant substance of the cathinone class. Pentedrone belongs to a group of compounds known as substituted cathinones. Pentedrone acts as a norepinephrine-dopamine reuptake inhibitor (NDRI).

    Dose Information TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Insufflated 2-5mg 5-10mg 10-20mg 20mg+
    Oral 5-10mg 10-15mg 15-25mg 25mg+
    Rectal 2-5mg 5-10mg 10-20mg 20mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TripSit PsychonautWiki

    ROA Onset Peak Offset After Effects Total
    Insufflated 6-12 min 30-90 min 30-90 min 1-8 hrs 1.1-3.2 hrs
    Oral 12-30 min 1-2 hrs 1-2 hrs 1-10 hrs 2.2-4.5 hrs

    Effect Profile

    6 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Stimulant 3.8
    Moderate 4/10

    Strong anxiety/jitters and euphoria with mild stimulation

    Stimulation / Energy ×3
    4
    stimulation alertness enhancement
    Euphoria / Mood Lift ×2
    9
    physical euphoria cognitive euphoria euphoria
    Focus / Productivity ×2
    0
    Anxiety / Jitters ×1
    10
    anxiety increased heart rate teeth grinding vasoconstriction
    Based on reports from:

    Add missing routes to PsychonautWiki Journal

    The PsychonautWiki Journal app already has Pentedrone, but its built-in entry only covers Insufflated, Oral. Here are the other routes we have data for. You can't edit a built-in substance, but you can add a Custom Unit for any of these routes to log it.

    ⬇ Download import file Import this file as custom substances and you get "Pentedrone (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.
    Custom Unit doses
    • Rectalcommon ~ 7.5 mg
    Dose & duration (reference)
    Pentedrone: routes the PsychonautWiki Journal app is missing
    Source: SubstanceSearch (substancesearch.com)
    
    Rectal dose (mg): light 2-5 Β· common 5-10 Β· strong 10-20 Β· heavy 20+
    
    Rectal duration: after-effects 1-12h
    
    Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Custom Units carry a single dose per route, so the full ranges live in the reference above. A route's suggested dose is the midpoint of its common range. Ranges are harm-reduction guidance, not a prescription.

    Tolerance

    Build-up develops rapidly, often within a single session; compulsive redosing common
    Reset a few days for acute tolerance

    Tolerance Decay

    Full tolerance 1h Half tolerance 7d Baseline ~14d

    Effects Erowid

    Aggregated from 6 Erowid experience reports

    Positive Effects 3

    Stimulation 83.3% 70%
    Euphoria 50.0% 70%
    Tactile Enhancement 50.0% 70%

    Adverse Effects 1

    Anxiety 66.7% 70%

    Combinations TripSit

    Cross-Check Pentedrone with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

    Erowid 3 reports 1 positive 1 neutral 1 cautionary visit
    On High Alert neutral exp #104485

    Pentedrone, (+-)-phenyl-2-(methylamino)penta-1-one. Sourced from a RC chem supplier. Experience takes place at a close friendΒ’s house, very comfortable setting with three friends.

    Curious Chemist · 10 mg insufflated / 10 mg insufflated / 10 mg insufflated / 10 mg insufflated
    Mediocre cautionary exp #118764

    A Mediocre Experience I recently acquired some Pentedrone (tested on FTIR) and decided I wanted to try vaping it after having tried it insufflated a few times. I found a few small posts of people saying they had tried vaping it but no full reports of the experience so here we go :) I have experience with a few other st...

    Lizardtime · 12 mg vaporized / 24 mg vaporized / 24 mg vaporized / 32 mg vaporized
    A Most Enjoyable RC positive exp #107448

    I have never done a experience report for the various things I have tried throughout my journey through space and time, but I figured it was time to shed some light on this since it has very little on the webs about peoples dabbling.

    easy-z · repeated vaporized
    Bluelight 1 thread 1 neutral visit
    Pentedrone First Time 4 Days Straight Powered By Penta neutral

    Hello, it's going to be my first trip report, I'd like to apologize first for my eventual mistakes and grammar issues (I'm a foreigner), thanks I am in love with stimulants and the last ones I frequently used on different occasions were 3-fa, 4-fa, methiopropamine, and mephedrone.

    scraped 2026-03-14

    Helpful Links