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    Pentedrone molecular structure

    Pentedrone Stats & Data

    Stimulant Research-chemical
    PubChem CID 57501499
    NPS DataHub
    MW227.73
    FormulaC12H18ClNO
    CAS879669-95-1
    IUPAC(±)-1-Phenyl-2-(methylamino)pentan-1-one.hydrochloride
    SMILES[Cl-].CCCC(NC)C(=O)c1ccccc1.[H+]
    InChIKeyMACVVBRQAPNUKT-UHFFFAOYSA-N
    Phenethylamines; 2020/1. Von 2-Phenethylamin abgeleitete Verbindungen; 2021/1. Von 2-Phenethylamin abgeleitete Verbindungen; 2022/1. Von 2-Phenethylamin abgeleitete Verbindungen
    Chemical Class Cathinone
    Psychoactive Class Stimulant

    Pharmacology

    DrugBank

    Receptor Profile

    Receptor Actions

    Inhibitors
    Norepinephrine-dopamine reuptake inhibitor (NDRI)
    Other
    minimal serotonin activity

    Toxicity

    PsychonautWiki

    The toxicity and long-term health effects of recreational pentedrone use do not seem to have been studied in any scientific context and the exact toxic dosage is unknown. This is because pentedrone has a very short history of human usage. Early anecdotal evidence from people who have tried pentedrone within the community suggests that there do not seem to be any negative health effects attributed to simply trying this substance at low to moderate doses by itself and using it in a sparing and controlled fashion (but nothing can be completely guaranteed). It is strongly recommended that one use harm reduction practices when using this substance.

    Effect Profile

    Curated + 6 Reports
    Stimulant 3.8

    Strong anxiety/jitters and euphoria with mild stimulation

    Stimulation / Energy×3
    4
    Euphoria / Mood Lift×2
    9
    Focus / Productivity×2
    0
    Anxiety / Jitters×1
    10
    Based on reports from:
    Erowid Experience Reports PsychonautWiki Pentedrone

    Tolerance & Pharmacokinetics

    drugs.wiki

    Tolerance Decay

    Full tolerance 1h Half tolerance 7d Baseline ~14d

    Experience Report Analysis

    Erowid
    6 Reports
    2013–2025 Date Range
    6 With Age Data
    5 Effects Detected

    Demographics

    Gender Distribution

    Age Distribution

    Reports Over Time

    Effect Analysis

    Erowid

    Effects aggregated from 6 experience reports (6 Erowid)

    6 Reports
    5 Effects Detected
    3 Positive
    1 Adverse
    1 Neutral

    Effect Sentiment Distribution

    Confidence Distribution

    Positive Effects 3

    Stimulation 83.3% 70%
    Euphoria 50.0% 70%
    Tactile Enhancement 50.0% 70%

    Adverse Effects 1

    Anxiety 66.7% 70%

    Real-World Dose Distribution

    62K Doses

    From 11 individual dose entries

    Insufflated (n=9)

    Median: 10.0mg 25th: 8.0mg 75th: 10.0mg 90th: 10.0mg
    mg/kg median: 0.118 mg/kg 75th: 0.147

    Form / Preparation

    Most common forms and preparations reported

    Read full reports on Erowid →

    Legal Status

    Country Status Notes
    Brazil Possession, production and sale is illegal as it is listed on Portaria SVS/MS nº 344.
    China As of October 2015 Pentedrone is a controlled substance
    Czech Republic Pentedrone is banned in the Czech Republic.
    Germany Pentedrone is an Anlage II controlled drug
    Switzerland Pentedrone is a controlled substance specifically named under Verzeichnis D.
    United Kingdom Pentedrone is a Class B drug in the United Kingdom as a result of the cathinone catch-all clause.
    United States On January 28, 2014, the DEA listed it, along with 9 other synthetic cathinones, on the Schedule 1 with a temporary ban, effective February 27, 2014.

    References

    Data Sources

    Cited References

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