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    Pentedrone molecular structure

    Pentedrone Stats & Data

    NPS DataHub
    MW227.73
    FormulaC12H18ClNO
    CAS879669-95-1
    IUPAC(±)-1-Phenyl-2-(methylamino)pentan-1-one.hydrochloride
    SMILES[Cl-].CCCC(NC)C(=O)c1ccccc1.[H+]
    InChIKeyMACVVBRQAPNUKT-UHFFFAOYSA-N
    Phenethylamines; 2020/1. Von 2-Phenethylamin abgeleitete Verbindungen; 2021/1. Von 2-Phenethylamin abgeleitete Verbindungen; 2022/1. Von 2-Phenethylamin abgeleitete Verbindungen
    Chemical Class Cathinone
    Psychoactive Class Stimulant

    Receptor Profile

    Receptor Actions

    Inhibitors
    Norepinephrine-dopamine reuptake inhibitor (NDRI)
    Other
    minimal serotonin activity

    Effect Profile

    Curated + 6 Reports
    Stimulant 3.8

    Strong anxiety/jitters and euphoria with mild stimulation

    Stimulation / Energy×3
    4
    Euphoria / Mood Lift×2
    9
    Focus / Productivity×2
    0
    Anxiety / Jitters×1
    10

    Tolerance & Pharmacokinetics

    drugs.wiki

    Tolerance Decay

    Full tolerance 1h Half tolerance 4d Baseline ~5d

    Experience Report Analysis

    Erowid
    6 Reports
    2013–2025 Date Range
    6 With Age Data
    5 Effects Detected

    Demographics

    Gender Distribution

    Age Distribution

    Reports Over Time

    Effect Analysis

    Erowid

    Effects aggregated from 6 experience reports (6 Erowid)

    6 Reports
    5 Effects Detected
    3 Positive
    1 Adverse
    1 Neutral

    Effect Sentiment Distribution

    Confidence Distribution

    Positive Effects 3

    Stimulation 83.3% 70%
    Euphoria 50.0% 70%
    Tactile Enhancement 50.0% 70%

    Adverse Effects 1

    Anxiety 66.7% 70%

    Real-World Dose Distribution

    62K Doses

    From 11 individual dose entries

    Insufflated (n=9)

    Median: 10.0mg 25th: 8.0mg 75th: 10.0mg 90th: 10.0mg
    mg/kg median: 0.118 mg/kg 75th: 0.147

    Form / Preparation

    Most common forms and preparations reported

    Legal Status

    Country Status Notes
    Brazil Possession, production and sale is illegal as it is listed on Portaria SVS/MS nº 344.
    China As of October 2015 Pentedrone is a controlled substance
    Czech Republic Pentedrone is banned in the Czech Republic.
    Germany Pentedrone is an Anlage II controlled drug
    Switzerland Pentedrone is a controlled substance specifically named under Verzeichnis D.
    United Kingdom Pentedrone is a Class B drug in the United Kingdom as a result of the cathinone catch-all clause.
    United States On January 28, 2014, the DEA listed it, along with 9 other synthetic cathinones, on the Schedule 1 with a temporary ban, effective February 27, 2014.
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