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    Phenmetrazine

    Aliases: Preludin

    Stimulant

    Summary TripSit

    Stimulant drug that was previously used as an appetite suppresant, has been withdrawn from the market, due to concerns of abuse and addiction. Usually produces less nervousness, euphoria, and insomnia than drugs of the amphetamine family. Also as a study concluded, it is slightly more effective than dextroamphetamine as a weight loss agent.

    Dose Information TripSit

    ROA Light Common Strong Heavy
    Oral - 25-50mg - -
    Light Common Strong Heavy

    Onset, Duration & After-effects TripSit

    ROA Onset Peak After Effects Total
    Oral 15-30 min 4-8 hrs 1-12 hrs 4.2-8.5 hrs

    Effect Profile

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Stimulant 4.5
    Moderate 4/10

    Strong anxiety/jitters and euphoria with moderate stimulation

    Stimulation / Energy ×3
    6
    stimulation wakefulness alertness enhancement
    Euphoria / Mood Lift ×2
    9
    physical euphoria cognitive euphoria euphoria
    Focus / Productivity ×2
    0
    ⚠ Anxiety / Jitters ×1
    10
    anxiety increased heart rate teeth grinding vasoconstriction
    Based on reports from:
    Erowid Experience Reports PsychonautWiki Phenmetrazine
    View methodology →

    Tolerance

    Build-up develops over days to weeks of regular use
    Reset 3–7 days for acute tolerance; longer for full reset

    Tolerance Decay

    Full tolerance 1d Half tolerance 10d Baseline ~18d

    Effects

    Positive
    • Stimulation
    • Physical euphoria
    • Muscle relaxation
    Negative
    • Increased heart rate
    • Nausea
    • Vasoconstriction
    • Respiratory depression
    • Teeth grinding
    • Insomnia
    Neutral
    • Sedation
    Positive
    • Alertness enhancement
    • Cognitive euphoria
    • Euphoria
    • Anxiety suppression
    • Wakefulness
    Negative
    • Anxiety
    • Compulsive redosing
    • Dizziness
    Neutral
    • Talkativeness
    • Time distortion
    Positive
    • Increased music appreciation
    • Increased libido
    • Tactile enhancement
    • Color enhancement
    Negative
    • Light sensitivity
    • Disinhibition
    • Appetite suppression
    • Dehydration
    • Double vision
    Neutral
    • Dulled perception
    Phenmetrazine's nerd page Pharmacology, chemical data, effect profiles, and more
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    Helpful Links

    📘 Experience Reports 📖 TripSit 📖 PsychonautWiki