Phenmetrazine
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 1 source
- partial dose data
- duration data present
- PubChem toxicity data
- 1 source
- partial dose data
- duration data present
- PubChem toxicity data
Aliases: Preludin
Summary
Stimulant drug that was previously used as an appetite suppresant, has been withdrawn from the market, due to concerns of abuse and addiction. Usually produces less nervousness, euphoria, and insomnia than drugs of the amphetamine family. Also as a study concluded, it is slightly more effective than dextroamphetamine as a weight loss agent.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | - | 25-50mg | - | - |
Onset, Duration & After-effects
| ROA | Onset | Peak | Total |
|---|---|---|---|
| Oral | 15-30 min | 4-8 hrs | 4-8 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong anxiety/jitters and euphoria with moderate stimulation
Add to PsychonautWiki Journal
The PsychonautWiki Journal logging app doesn't include every substance. To track Phenmetrazine there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:
Phenmetrazine Source: SubstanceSearch (substancesearch.com) Oral dose (mg): common 25-50 Oral duration: onset 15-30m · peak 4-8h · total 4-8h · after-effects 1-12h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 37.5 mg (Oral).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
- Stimulation
- Physical euphoria
- Muscle relaxation
- Increased heart rate
- Nausea
- Vasoconstriction
- Respiratory depression
- Teeth grinding
- Insomnia
- Sedation
- Alertness enhancement
- Cognitive euphoria
- Euphoria
- Anxiety suppression
- Wakefulness
- Anxiety
- Compulsive redosing
- Dizziness
- Talkativeness
- Time distortion
- Increased music appreciation
- Increased libido
- Tactile enhancement
- Color enhancement
- Light sensitivity
- Disinhibition
- Appetite suppression
- Dehydration
- Double vision
- Dulled perception
Helpful Links
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