PPAP
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 2 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 18 combo interactions documented
- classified Research-chemical
- 2 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 18 combo interactions documented
- classified Research-chemical
Aliases: Dppea, Mk-306, N,ฮฑ-dipropylphenethylamine
Summary
PPAP's sublingual route can irritate mucosa and its effect curve plateaus quickly. Tolerance tends to fade after roughly three days, but reagent testing and sub-10 mg allergy checks remain best practice. Unlike traditional stimulants, PPAP enhances neurotransmitter release only in response to neural activity rather than causing uncontrolled monoamine flooding.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 10-30mg | 30-50mg | 50-100mg | 100mg+ |
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 30-60 min | 10-30 min | 2-3 hrs | 2-5 hrs | 4-7 hrs |
| Sublingual / Buccal | - | - | 1-3 hrs | 1-2 hrs | 2-5 hrs |
| Insufflated | 5-10 min | - | 1-3 hrs | 1-2 hrs | 2.08-5.17 hrs |
| Intramuscular | 2-5 min | - | 1-3 hrs | 1-2 hrs | 2.03-5.08 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Moderate euphoria, focus, and anxiety/jitters with mild stimulation
Add to PsychonautWiki Journal
The PsychonautWiki Journal logging app doesn't include every substance. To track PPAP there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:
PPAP Source: SubstanceSearch (substancesearch.com) Oral dose (mg): threshold 10 ยท light 10-30 ยท common 30-50 ยท strong 50-100 ยท heavy 100+ Sublingual / Buccal dose (mg): threshold 3 Insufflated dose (mg): threshold 2 Intramuscular dose (mg): threshold 2 Oral duration: onset 0.5-1h ยท come-up 10-30m ยท peak 2-3h ยท offset 2-5h ยท total 4-7h Sublingual / Buccal duration: peak 1-3h ยท offset 1-2h ยท total 2-5h ยท after-effects 1-4h Insufflated duration: onset 5-10m ยท peak 1-3h ยท offset 1-2h ยท total 2.08-5.17h ยท after-effects 1-4h Intramuscular duration: onset 2-5m ยท peak 1-3h ยท offset 1-2h ยท total 2.03-5.08h ยท after-effects 1-4h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 40 mg (Oral).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session โ the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Patterns are based on user reports: repeated daily dosing for multiple days appears to reduce desired effects and increase anxiety/insomnia; spacing use by several days to a week helps preserve efficacy. Cross-tolerance with other CAE/MAE agents (e.g., BPAP) is plausible but unquantified. Data quality is limited.
Cross-Tolerances
Effects
- Stimulation
- Stamina enhancement
- Physical euphoria
- Pain relief
- Increased heart rate
- Increased perspiration
- Respiratory depression
- Nausea
- Sedation
- Itchiness
- Increased motivation
- Focus enhancement
- Analysis enhancement
- Cognitive euphoria
- Anxiety suppression
- Dream potentiation
- Irritability
- Anxiety
- Constipation
- Dizziness
- Increased music appreciation
- Increased libido
- Libido enhancement
- Dehydration
- Appetite suppression
- Light sensitivity
- Double vision
- Spontaneous physical sensations
- Internal hallucination
- Dulled perception
Combinations
Cross-Check PPAP with another substanceHelpful Links
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