PPAP
Aliases: Dppea, Mk-306, N,ฮฑ-dipropylphenethylamine
Categories
Summary
PPAP's sublingual route can irritate mucosa and its effect curve plateaus quickly. Tolerance tends to fade after roughly three days, but reagent testing and sub-10 mg allergy checks remain best practice. Unlike traditional stimulants, PPAP enhances neurotransmitter release only in response to neural activity rather than causing uncontrolled monoamine flooding. Animal studies show doubled dopamine/norepinephrine release without overflow at 2 mg/kg i.p., with minimal stereotypy until 25-50 mg/kg. Human self-experiments describe clear focus, wakefulness and pro-social energy at 20-80 mg oral, with effects plateauing around 3 hours and minimal crash.
Dose Information
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Peak | Offset | After Effects |
|---|---|---|---|---|
| Oral | 30-60 min | 1-3 hrs | 1-2 hrs | 1-4 hrs |
| Sublingual / Buccal | - | 1-3 hrs | 1-2 hrs | 1-4 hrs |
| Insufflated | 5-10 min | 1-3 hrs | 1-2 hrs | 1-4 hrs |
| Intramuscular | 2-5 min | 1-3 hrs | 1-2 hrs | 1-4 hrs |
Tolerance
Build-up
develops over days to weeks of regular use
Reset
3โ7 days for acute; 1โ3 weeks for full reset
Effects
Positive
- Stimulation
- Stamina enhancement
- Physical euphoria
- Pain relief
Negative
- Increased heart rate
- Increased perspiration
- Respiratory depression
- Nausea
- Sedation
- Itchiness
Positive
- Increased motivation
- Focus enhancement
- Analysis enhancement
- Cognitive euphoria
- Anxiety suppression
- Dream potentiation
Negative
- Irritability
- Anxiety
- Constipation
- Dizziness
Positive
- Increased music appreciation
- Increased libido
- Libido enhancement
Negative
- Dehydration
- Appetite suppression
- Light sensitivity
- Double vision
- Spontaneous physical sensations
- Internal hallucination
- Dulled perception