Introduction I've tried pramiracetam before using pill dosage. I found the effects to be very beneficial for study and test preparation/performance. The dosage I was utilizing were 300 mg pills until I later found out about bulk powder where I went from spending $3.89/gram to $1.20/gram for purchase.
Pramiracetam
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 6 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- PubChem toxicity data
- classified Research-chemical
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 6 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- PubChem toxicity data
- classified Research-chemical
Aliases: Remen, Ci-879, Pramistar, Neupramir
Summary
Pramiracetam (also known as Pramistar) is a nootropic stimulant of the racetam class. It is a derivative of piracetam, which has been studied as a cognitive enhancing agent. In parts of Europe, pramiracetam is marketed as a prescription drug by Menarini under the brand name Pramistar as a treatment for memory and attention deficits in aging people with neurodegenerative and vascular dementias.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 250-500mg | 500-800mg | 800-1200mg | 1200mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Peak | Offset | Total |
|---|---|---|---|---|
| Oral | 30-90 min | 2-3 hrs | 2-4 hrs | 4-6 hrs |
Effect Profile
4 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Stimulant
5.5
Strong
6/10
Moderate stimulation and focus with mild anxiety/jitters, low euphoria
Stimulation / Energy
×3
7
stimulation
stamina enhancement
wakefulness
Euphoria / Mood Lift
×2
2
motivation enhancement
Focus / Productivity
×2
7
focus enhancement
memory enhancement
motivation enhancement
Anxiety / Jitters
×1
5
increased heart rate
teeth grinding
Based on reports from:
Tolerance
Build-up
develops over days to weeks of regular use
Reset
3–7 days for acute tolerance; longer for full reset
Tolerance Decay
Full tolerance
1d
Half tolerance
10d
Baseline
~18d
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
Positive
- Stimulation
- Stamina Enhancement
- Subtle Stimulation
Negative
- Headaches
- Increased heart rate
- Headache
- Fatigue
- Teeth grinding
- Gastrointestinal Distress
- Body odor alteration
Positive
- Focus Enhancement
- Memory Enhancement
- Mindfulness
- Wakefulness
- Thought Connectivity
- Motivation Enhancement
- Anxiety Suppression
- Dream Potentiation
- Addiction Suppression
Negative
- Emotion Suppression
Positive
- Visual Acuity Enhancement
- Auditory Acuity Enhancement
- Color Enhancement
- Bodily Control Enhancement
- Acuity Enhancement
Negative
- Light sensitivity
- Appetite Suppression
- Appetite suppression
- Dehydration
- Olfactory Intensification
Community Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.
Erowid 2 reports 2 neutral visit
I ordered some Pramiracetam capsules from a reputable-looking US-based provider in hopes of experiencing the drugs purported Nootropic effects. The order itself cost about $30 incl. shipping for 60 250mg capsules.
Pramiracetam's nerd page
Pharmacology, chemical data, effect profiles, and more
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Helpful Links
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