Promethazine
Aliases: Phenergan, Promethazine hcl
Summary
Promethazine (commonly sold as Phenergan or Lergigan) is a depressant substance of the phenothiazine class. Alongside codeine, it is popularly known as one of the active two ingredients in "lean". It acts as an antihistamine.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 12.5-25mg | 25-50mg | 50-100mg | 100mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 15-30 min | 20-60 min | 4-8 hrs | 3-5 hrs | 7.6-14.5 hrs |
Tolerance
Build-up
sedative and antiemetic tolerance develops over 1–2 weeks
Reset
a few days
Tolerance Decay
Full tolerance
3d
Half tolerance
4d
Baseline
~5d
Effects
Aggregated from 35 Erowid experience reports
Positive Effects 10
Sedation
45.7%
70%
Euphoria
28.6%
70%
Stimulation
22.9%
70%
Anxiety Suppression
20.0%
70%
Focus Enhancement
17.1%
70%
Music Enhancement
17.1%
70%
Tactile Enhancement
14.3%
70%
Pain Relief
8.6%
70%
Color Enhancement
8.6%
70%
Empathy
8.6%
70%
Adverse Effects 5
Nausea
25.7%
70%
Confusion
11.4%
70%
Motor Impairment
11.4%
70%
Memory Suppression
8.6%
70%
Muscle Tension
8.6%
70%
Pill Identifiers
16
known pill identifiers on record — view imprints, colors, shapes, and images
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Promethazine's nerd page
Pharmacology, chemical data, effect profiles, and more
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