I took 2 25 mg tabs at 8:30AM....... By 9:15 I had a pleasant, sedated feeling. A kind of euphoric side effect as well, but not like the euphoric sensations of an Opioid. I noticed if I took this at beditme I slept soundly. But by taking it while wide awake, it produced a more noticable lightheadedness.
Promethazine
Well-documented
Well-documented
Multiple authoritative sources agree on dosing and effects.
- 5 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- PubChem toxicity data
Well-documented
Multiple authoritative sources agree on dosing and effects.
- 5 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- PubChem toxicity data
Aliases: Phenergan, Promethazine hcl
Summary
Promethazine (commonly sold as Phenergan or Lergigan) is a depressant substance of the phenothiazine class. Alongside codeine, it is popularly known as one of the active two ingredients in "lean". It acts as an antihistamine.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 12.5-25mg | 25-50mg | 50-100mg | 100mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 15-30 min | 20-60 min | 4-8 hrs | 3-5 hrs | 4-8 hrs |
Tolerance
Build-up
sedative and antiemetic tolerance develops over 1–2 weeks
Reset
a few days
Tolerance Decay
Full tolerance
3d
Half tolerance
4d
Baseline
~5d
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
Aggregated from 35 Erowid experience reports
Positive Effects 10
Sedation
45.7%
70%
Euphoria
28.6%
70%
Stimulation
22.9%
70%
Anxiety Suppression
20.0%
70%
Focus Enhancement
17.1%
70%
Music Enhancement
17.1%
70%
Tactile Enhancement
14.3%
70%
Pain Relief
8.6%
70%
Color Enhancement
8.6%
70%
Empathy
8.6%
70%
Adverse Effects 5
Nausea
25.7%
70%
Confusion
11.4%
70%
Motor Impairment
11.4%
70%
Memory Suppression
8.6%
70%
Muscle Tension
8.6%
70%
Community Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.
Erowid 8 reports 1 positive 4 neutral 3 cautionary visit
Okay, Im finally writing in on something that went wrong. Darn. I suppose I couldve prevented the situation by reading up more thoroughly on side effects, but dosages at which these side effects present themselves is not really found anywhere I looked, so maybe not.
Promethazine Fun Sporting a niggling hangover that just wouldnt go away, I started looking for something to take which would dull the hangover or replace the feeling of it with a different feeling all together.
I have taken promethazine before, yet in combonation with meperidine in my favorite capsule called Mepergan Forte. Yet my friend recentley was prescribed a bottle of 25 mg promethazine tabs only. Of course he called me up to make a few bucks. That night at around 6 PM I took 3 of the tablets.
A Promethazine Affair My roommate had been having severe stomach issues, thus was prescribed Promethazine for nausea. After about a week of taking them, she came up to me and said 'you have to try these'.
Promethazine Nightmare I have found very few reports or incidences online of such an experience with promethazine hydrochloride. I initially thought my dosage was in line with what was recommended, however from what I can tell, for the high dosage that I took other drugs are usually prescribed alongside it to help coun...
[Erowid Note: Driving while intoxicated, tripping, or extremely sleep deprived is dangerous and irresponsible because it endangers other people. Don't do it! ] I took four 25 mg pills of promethazine to give my night a kick, and began to feel slightly sedated and relaxed about 40 minutes in.
I've used benzo's very long, and im very tolerant and addicted to them. I wanted to try stopping, but suffered extreme withdrawal syptoms and didnt sleep a couple of days when I tried not taking them, I immedietly went back on them, and my doctor gave me phenergan, or promethazine which is supposedly less addictive and...
Bluelight 2 threads 2 neutral visit
To start off i had 25 drops of nutmeg essentials oil (about .5ml) this morning at about 11:00 After several hours the effects were minimal but still noticabel After little success I found out that promethazine can have phycotic effects when mixed with codiene which is a cough syrup.
I've heard promethazine (seasick or allergy pills) can have psychedelic effects much like weed numerous times but only ever used them for their actual purpose taking 1-2 at a time but after an ongoing lack of internet and smoking for 3 months I got extremely bored and decided to give this myth a test.
Pill Identifiers
16
known pill identifiers on record — view imprints, colors, shapes, and images
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Promethazine's nerd page
Pharmacology, chemical data, effect profiles, and more
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Helpful Links
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