Propoxyphene
Summary
Is an analgesic in the opioid family. It is intended for mild pain and for its antitussive effects. Has been taken off the market in Europe and the US due to concerns of fatal overdoses and heart arrhythmias.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 30-65mg | 65-100mg | 100-200mg | 200mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Peak | Total |
|---|---|---|---|
| Oral | 20-30 min | 1-3 hrs | 1.3-3.5 hrs |
Tolerance
Build-up
develops within days of regular use; analgesic tolerance faster than respiratory depression tolerance
Reset
7–14 days for partial reset; full reset may take weeks — tolerance loss greatly increases overdose risk
Tolerance Decay
Full tolerance
1d
Half tolerance
21d
Baseline
~35d
Effects
Aggregated from 13 Erowid experience reports
Positive Effects 7
Euphoria
53.8%
70%
Sedation
46.2%
70%
Music Enhancement
30.8%
70%
Tactile Enhancement
30.8%
70%
Empathy
23.1%
70%
Stimulation
23.1%
70%
Anxiety Suppression
23.1%
70%
Adverse Effects 1
Nausea
23.1%
70%
Pill Identifiers
4
known pill identifiers on record — view imprints, colors, shapes, and images
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Propoxyphene's nerd page
Pharmacology, chemical data, effect profiles, and more
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