Psilocin Stats & Data
SPCIYGNTAMCTRO-UHFFFAOYSA-NPharmacology
DrugBankMetabolism
Psilocin has known human metabolites that include (2S,3S,4S,5R)-6-[3-[2-(dimethylamino)ethyl-1H-indol-4-yl]oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid.
Receptor Profile
Receptor Actions
Subjective Effects
Physical
- Spontaneous tactile sensations: The "body high" of psilocin can be described as a pleasurable, warm, soft and all-encompassing tingling sensation. This maintains a consistent presence that steadily rises with the onset and hits its limit once the peak has been reached.
- Sedation: In terms of its effects on the physical energy levels of the tripper, psilocin is considered by most to be relaxing, stoning and mildly sedating. This sense of sedation is often accompanied by compulsive yawning.
- Runny nose
- Excessive yawning
- Watery eyes
- Nausea
- Changes in gravity
- Salivation
- Pupil dilation
Cognitive
- Current mind state enhancement
- Thought connectivity
- Novelty enhancement
- Time distortion
- Analysis enhancement: This effect is consistent in its manifestation and outrospection dominant.
- Déjà vu
- Personal bias suppression
- Feelings of predeterminism
- Immersion enhancement
- Conceptual thinking
- Direct communication with the subconscious
- Memory suppression
- Feelings of interdependent opposites
- Delusions
- Unity and interconnectedness
- Feelings of self-design
- Exposure to inner mechanics of consciousness
- Spirituality enhancement
- Enhancement and suppression cycles: This can be described as constant waves of extremely stimulated and profound thinking which are spontaneously surpassed in a cyclic fashion by waves of general thought suppression and mental intoxication. These two states seem to switch between each other in a consistent loop once every 20 - 60 minutes.
Sensory
- Enhancements
- Distortions
- Hallucinations
As for visual distortions and alterations, the effects experienced are detailed below:
- Drifting: (Melting, Flowing, Breathing and morphing) - In comparison to other psychedelics, this effect can be described as highly detailed, realistic, slow and smooth in motion and static in appearance.
- Tracers
- After images
- Symmetrical texture repetition
- Colour shifting
- Scenery slicing
Psilocin presents a full and complete array of possible visual enhancements which generally includes:
- Visual acuity enhancement
- Colour enhancement
- Pattern recognition enhancement
Psilocin and its various other forms produce a full range of high level hallucinatory states in a fashion that is more consistent and reproducible than that of many other commonly used psychedelics. These effects generally include:
- Transformations
- Internal hallucinations: (Autonomous entities, Settings, sceneries, and landscapes, Alterations in perspective and Scenarios and plots) - This effect is very consistent in dark environments at appropriately high dosages. They can be comprehensively described through their variations as lucid in believability, interactive in style, new experiences in content, autonomous in controllability, geometry-based in style and almost exclusively of a religious, spiritual, mystical, science fiction or transcendental nature in their overall theme.
Forked from Subjective Effect Documentation work by Josie Kins, April 2015. Via dose.wiki (CC0).
Psilocin is non-addictive, is not known to cause brain damage, and has an extremely low toxicity relative to dose. Similar to other psychedelic drugs, there are relatively few physical side effects associated with acute psilocin exposure. Various studies have shown that in reasonable doses in a careful context, it presents little to no negative cognitive, psychiatric or toxic physical consequences.
Carcinogenicity
No indication of carcinogenicity to humans (not listed by IARC).
Effect Profile
Curated + 12 ReportsModerate visuals with mild headspace and body load, low auditory effects
Strong sensory enhancement with moderate euphoria, low empathy and stimulation
Duration Timeline
BluelightTolerance & Pharmacokinetics
drugs.wikiTolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Cross-Tolerances
Experience Report Analysis
ErowidDemographics
Gender Distribution
Age Distribution
Reports Over Time
Effect Analysis
ErowidEffects aggregated from 12 experience reports (12 Erowid)
Effect Sentiment Distribution
Confidence Distribution
Positive Effects 8
Adverse Effects 3
Real-World Dose Distribution
62K DosesFrom 20 individual dose entries
Oral (n=13)
Form / Preparation
Most common forms and preparations reported
Legal Status
| Country | Status | Notes |
|---|---|---|
| Australia | Psilocin is considered a Schedule 9 prohibited substance in Australia under the Poisons Standard (October 2015). | A Schedule 9 substance is a substance which may be abused or misused, the manufacture, possession, sale or use of which should be prohibited by law except when required for medical or scientific research, or for analytical, teaching or training purposes with approval of Commonwealth and/or State or Territory Health Authorities. |
| Russia | Psilocin and psilocybin are banned in Russia, due to their status as narcotic drugs, with a criminal penalty for possession of more than 50 mg. | |
| United States | Psilocin is a Schedule I controlled substance in the United States since 1971. |
References
Cited References
- Bluelight: The Big and Dandy 4-HO-DMT Thread
- Drug-drug interactions between psychiatric medications and MDMA or psilocybin
- Drug-drug interactions involving classic psychedelics: A systematic review
- Erowid: Psilocin Experience Reports
- PsychonautWiki: Psilocin
- TiHKAL #18: 4-HO-DMT by Alexander Shulgin