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    ๐Ÿงช This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    Psilocin

    Aliases: 4-ho-dmt, 4-oh-dmt, Psilocine, Psilotsin

    Categories

    Psilocin structure

    Summary TheDrug.Wiki TripSit PsychonautWiki

    Psilocin is the pharmacologically active form of psilocybin and is rarely encountered as a pure synthetic compound. It is relatively unstable and readily forms blue degradation products when exposed to oxygen. Store in cool, dry, dark conditions. Unlike psilocybin mushrooms, pure psilocin has reduced nausea when taken on an empty stomach. Set and setting are critical to the experience.

    Perspectives

    “Something has started but I decide to join in a full dinner anyway. The effects develop right through the meal, with some hints of animal faces in the pork-chop bones. No movement, nothing flows, but it probably wouldnโ€™t take much effort. Another hour and I am dropping off already. The food? Somehow I doubt it. I would be completely unable to tell this from, say, 80 milligrams of MDMA except that I had a good appetite.”

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral BA ~50% 10-15mg 15-25mg 25-40mg 40mg+
    Insufflated 2.5-5mg 5-10mg 10-15mg 15mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects
    Oral 19-45 min 1.5-3.0 hrs 2.0-3.0 hrs 1.5-2.0 hrs 4.0-24.0 hrs
    Insufflated 4-10 min - 2.0-4.0 hrs - 3.0-12.0 hrs

    Tolerance

    Build-up develops rapidly after a single use
    Reset 7โ€“14 days for baseline

    Effects TheDrug.Wiki

    Positive
    • Physical euphoria
    • Physical Euphoria
    • Stimulation
    Negative
    • Nausea
    • Temperature Regulation Suppression
    • Nystagmus
    Neutral
    • Sedation
    • Excessive yawning
    • Dilated pupils
    • Difficulty Urinating
    Positive
    • Emotionality enhancement
    • Empathy enhancement
    • Cognitive euphoria
    • Analysis enhancement
    • Conceptual thinking
    • Thought connectivity
    • Unity and interconnectedness
    • Spirituality enhancement
    Negative
    Neutral
    • Time distortion
    • Ego dissolution
    Positive
    • Tactile enhancement
    • Colour enhancement
    • Visual acuity enhancement
    • Pattern recognition enhancement
    • Synaesthesia
    Negative
    Neutral
    • Perception of bodily heaviness
    • Spontaneous physical sensations
    • Changes in felt bodily form
    • Visual drifting
    • Internal hallucination
    • External hallucination

    Combinations TripSit

    PiHKAL / TiHKAL Shulgin

    TiHKAL #18: 4-HO-DMT

    “Something has started but I decide to join in a full dinner anyway. The effects develop right through the meal, with some hints of animal faces in the pork-chop bones. No movement, nothing flows, but it probably wouldnโ€™t take much effort. Another hour and I am dropping off already. The food? Somehow I doubt it. I would be completely unable to tell this from, say, 80 milligrams of MDMA except that I had a good appetite.”

    โ€” Alexander Shulgin, TiHKAL (with 6.6 mg phosphate ester, orally)

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