Summary
Benzodiazepine derivate drug, noral is prescribed for short term treatment of insomnia, and sleep maintenance. its MOA is very similar to Ambien and Sonata and substitutes for those in animal studies.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 7.5-10mg | 10-15mg | 15-30mg | 30mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Peak | After Effects | Total |
|---|---|---|---|---|
| Oral | 10-30 min | 6.0-12.0 hrs | 1.0-24.0 hrs | 360-0 min |
Tolerance
Build-up
develops over 1–4 weeks of daily use; hypnotic tolerance faster than anxiolytic tolerance
Reset
weeks to months depending on half-life and duration of use; taper recommended
Effects
Positive
- Stimulation
- Physical euphoria
- Muscle relaxation
Negative
- Motor impairment
- Increased heart rate
- Nausea
- Vasoconstriction
- Respiratory depression
- Teeth grinding
- Sedation
Positive
- Reduced anxiety
- Cognitive euphoria
- Euphoria
- Anxiety suppression
- Wakefulness
Negative
- Anxiety
- Compulsive redosing
- Dizziness
- Thought deceleration
- Time distortion
Positive
- Increased music appreciation
- Increased libido
- Tactile enhancement
- Color enhancement
Negative
- Disinhibition
- Appetite suppression
- Dehydration
- Light sensitivity
- Double vision
- Dulled perception