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    Quazepam molecular structure

    Quazepam Stats & Data

    Doral
    NPS DataHub
    MW386.8
    FormulaC17H11ClF4N2S
    CAS36735-22-5
    IUPAC7-chloro-5-(2-fluorophenyl)-1-(2,2,2-trifluoroethyl)-3H-1,4-benzodiazepine-2-thione
    SMILESFC(F)(F)CN1C(=S)CN=C(c2ccccc2F)c2cc(Cl)ccc12
    InChIKeyIKMPWMZBZSAONZ-UHFFFAOYSA-N
    2020/3. Benzodiazepine; 2021/3. Benzodiazepine; 2022/3. Benzodiazepine
    Chemical Class Benzodiazepine
    Psychoactive Class Depressant

    Pharmacology

    DrugBank
    Half-life 39 hours State Solid Metabolism Hepatic.

    Description

    Quazepam is a drug which is a benzodiazepine derivative. It induces impairment of motor function and has hypnotic properties. Quazepam is used to treat insomnia.

    Pharmacodynamics

    Quazepam is a benzodiazepine derivative. The main pharmacological action of quazepam is the enhancement of the neurotransmitter GABA at the GABAA receptor.

    Absorption

    Bioavailability is 29-35% following oral administration.

    Indication

    Used to treat insomnia.

    Effect Profile

    Curated
    Benzodiazepine 7.6

    Strong euphoria and anxiolysis with mild sedation, low cognitive impairment

    Anxiolysis×3
    8
    Sedation / Relaxation×2
    5
    Motor / Cognitive Impairment×1
    1
    Euphoria / Mood Lift×1
    10

    Tolerance & Pharmacokinetics

    drugs.wiki

    Tolerance Decay

    Full tolerance 3d Half tolerance 37d Baseline ~60d
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