Quazepam Stats & Data
Doral
NPS DataHub
MW386.8
FormulaC17H11ClF4N2S
CAS36735-22-5
IUPAC7-chloro-5-(2-fluorophenyl)-1-(2,2,2-trifluoroethyl)-3H-1,4-benzodiazepine-2-thione
SMILES
FC(F)(F)CN1C(=S)CN=C(c2ccccc2F)c2cc(Cl)ccc12InChIKey
IKMPWMZBZSAONZ-UHFFFAOYSA-N
Chemical Class
Benzodiazepine
Psychoactive Class
Depressant
Pharmacology
DrugBank
Half-life 39 hours
State Solid
Metabolism Hepatic.
Description
Quazepam is a drug which is a benzodiazepine derivative. It induces impairment of motor function and has hypnotic properties. Quazepam is used to treat insomnia.
Pharmacodynamics
Quazepam is a benzodiazepine derivative. The main pharmacological action of quazepam is the enhancement of the neurotransmitter GABA at the GABAA receptor.
Absorption
Bioavailability is 29-35% following oral administration.
Indication
Used to treat insomnia.
Effect Profile
Curated
Benzodiazepine
7.6
Strong euphoria and anxiolysis with mild sedation, low cognitive impairment
Anxiolysis×3
8
Sedation / Relaxation×2
5
Motor / Cognitive Impairment×1
1
Euphoria / Mood Lift×1
10
Based on reports from:
Tolerance & Pharmacokinetics
drugs.wikiTolerance Decay
Full tolerance
3d
Half tolerance
37d
Baseline
~60d