Summary
Secobarbital, also known as secobarbitone in British English and by the brand name Seconal, is a short-acting psychoactive drug of the barbiturate class which produces powerful anxiolytic, hypnotic, muscle relaxant and amnesic effects. The combination drug Tuinal has a combination of secobarbital and amobarbital. Secobarbital is used medically as a hypnotic for the short-term treatment of insomnia and as an anticonvulsant in emergency situations, such as status epilepticus. Secobarbital works in a similar fashion to benzodiazepines, however, barbiturates bind to a different and distinct allosteric site on the GABAA receptor.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 25-50mg | 50-150mg | 150-300mg | 300mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Peak | Offset | After Effects | Total |
|---|---|---|---|---|---|
| Oral | 15-60 min | 4-8 hrs | 2-4 hrs | 1-24 hrs | 360-0 min |
Tolerance
Build-up
develops over 1–4 weeks of daily use; hypnotic tolerance faster than anxiolytic tolerance
Reset
weeks to months depending on half-life and duration of use; taper recommended
Effects
Positive
- Physical Euphoria
- Muscle Relaxation
- Pain Relief
- Anxiolytic
- Muscle relaxant
Negative
- Motor impairment
- Respiratory Depression
- Sedation
- Sedative
- Dystaxia
Positive
- Anxiety Suppression
- Cognitive Euphoria
Negative
- Motor Control Loss
- Amnesia
- Thought Deceleration
- Compulsive Redosing
- Language Suppression
- Delusions of Sobriety
- Analysis Suppression
- Emotion Suppression
Positive
- Tracers
- Increased Music Appreciation
Negative
- Disinhibition
- Decreased Libido
- Acuity Suppression
- Dulled perception
- Metallic Taste
- Visual Drifting
- External Hallucinations
- Auditory Hallucinations