Sufentanil
Well-documented
Well-documented
Multiple authoritative sources agree on dosing and effects.
- 3 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 19 combo interactions documented
- toxicity data (PsychonautWiki, PubChem)
- 3 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 19 combo interactions documented
- toxicity data (PsychonautWiki, PubChem)
Aliases: Dsuvia, Sufenta, Chronogesic
Summary
Sufentanil, also known as sufentanyl and by the brand name Sufenta, is an extremely potent synthetic anilidopiperidine opioid analgesic. Sufentanil has a rapid onset and short mechanism and is used medically as an analgesic in surgical procedures or for the management of post-operative pain. Sufentanil is roughly 500 to 1,000 times more potent than pharmaceutical grade morphine and is approximately 10 times more potent than pharmaceutical grade fentanyl.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Intravenous | 1-5μg | 5-10μg | 10-25μg | 25μg+ |
Onset, Duration & After-effects
| ROA | Onset | Peak | Offset | Total |
|---|---|---|---|---|
| Intravenous | 1-2 min | 5-10 min | 15-30 min | 21-42 min |
| Epidural | 5-15 min | 30-60 min | 1-2 hrs | 1.58-3.25 hrs |
| Sublingual | 10-30 min | 60-90 min | 1-2 hrs | 2.17-4 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong euphoria and sedation with moderate itching/nausea, mild pain relief
Add missing routes to PsychonautWiki Journal
The PsychonautWiki Journal app already has Sufentanil, but its built-in entry only covers Intravenous. Here are the other routes we have data for. You can't edit a built-in substance, but you can add a Custom Unit for any of these routes to log it.
Sufentanil: routes the PsychonautWiki Journal app is missing Source: SubstanceSearch (substancesearch.com) Sublingual dose (µg): threshold 15ug Sublingual duration: onset 10-30m · peak 1-1.5h · offset 1-2h · total 2.17-4h · after-effects 2-8h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Custom Units carry a single dose per route, so the full ranges live in the reference above. A route's suggested dose is the midpoint of its common range. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
- Pain Relief
- Physical Euphoria
- Cough Suppression
- Muscle Relaxation
- Respiratory Depression
- Nausea
- Sedation
- Difficulty Urinating
- Itchiness
- Pupil Constriction
- Anxiety Suppression
- Reduced anxiety
- Cognitive Euphoria
- Dream Potentiation
- Euphoria
- Feelings of relaxation
- Constipation
- Compulsive Redosing
- Drowsiness
- Changes in focus
- Decreased Libido
- Dehydration
- Double Vision
- Appetite Suppression
- Orgasm Suppression
- Orgasm depression
- Acuity Suppression
- Disinhibition
- Light sensitivity
- Dulled perception
Combinations
Cross-Check Sufentanil with another substanceHelpful Links
Report an issue or suggest an edit
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