THC
Aliases: Marinol, Cesamet, Syndros, Dronabinol, Δ9--tetrahydrocannabinol, weed, marijuana, dagga, hash, cannabis, δ9-thc, delta9-tetrahydrocannabinol, delta9-thc
Categories
Summary
Dronabinol is a synthetic form of delta-9-THC, the primary active ingredient in Cannabis. It is presecribed as an appetite stimulant and for treating neuropathic pain in the United States. Dronabinol is one of the examples used to point out the inconsistency of the U.S. and U.N. controlled substance rules and definitions because THC both falls under the classifications as "no accepted medical use" and "accepted medical use".
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 10-20mg | 20-30mg | 30-50mg | 50mg+ |
| Smoked | 10-20mg | 20-60mg | 60-100mg | 100mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Peak | After Effects | Total |
|---|---|---|---|---|
| Oral | 1800-0 min | 4.0-12.0 hrs | 1.0-4.0 hrs | 240-0 min |
| Smoked | 1-10 min | 1.0-4.0 hrs | 2.0-24.0 hrs | 60-0 min |
Tolerance
Build-up
develops gradually over weeks of daily use; subjective effects diminish before physiological tolerance
Reset
2–4 weeks for most users; heavy users may need longer (up to 90 days for full CB1 receptor reset)
Cross-tolerance
Effects
Positive
- Stimulation
- Mental/physical stimulation
Negative
- Increased heart rate
- Pupil dilation
- Nausea
- Insomnia
- Vasoconstriction
- Restlessness
- Sedation
- Decreased appetite
Positive
- Alertness enhancement
- Euphoria
- Cognitive euphoria
- Wakefulness
- Empathy
Negative
- Anxiety
- Confusion
- Compulsive redosing
- Talkativeness
- Time distortion
Positive
- Increased music appreciation
- Color enhancement
- Tactile enhancement
- Brightened colour
Negative
- Light sensitivity
- Appetite suppression
- Dehydration
- Disinhibition
- Drifting
- Dulled perception