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    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    Thiopropamine Limited data
    Limited data
    Sparse data. Doses and effects may be unreliable or untested.
    • 1 source
    • 1 ROA with full dose ladder
    • duration data present
    • classified Research-chemical

    Aliases: Tpa, Normethiopropamine, A-methyl-2-thipheneethanamine

    Stimulant Research-chemical

    Summary TripSit

    A substance that is closely related to Methiopopramine (MPA). Is roughly about 1/3rd the potency of amphetamine, differs from amphetmine from the phenyl ring is switched with a thiophene ring.

    Dose Information TripSit

    ROA Light Common Strong Heavy
    Oral 20-50mg 50-100mg 100-125mg 125mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TripSit

    ROA Onset Peak After Effects
    Oral 15-45 min 1-4 hrs 1-3 hrs

    Effect Profile

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Stimulant 4.5
    Moderate 4/10

    Strong anxiety/jitters and euphoria with moderate stimulation

    Stimulation / Energy ×3
    6
    stimulation wakefulness alertness enhancement
    Euphoria / Mood Lift ×2
    9
    physical euphoria cognitive euphoria euphoria
    Focus / Productivity ×2
    0
    ⚠ Anxiety / Jitters ×1
    10
    anxiety increased heart rate teeth grinding vasoconstriction
    View methodology →

    Add to PsychonautWiki Journal

    The PsychonautWiki Journal logging app doesn't include every substance. To track Thiopropamine there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:

    ⬇ Download import file Import this file as custom substances and you get "Thiopropamine (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.
    Name
    Thiopropamine
    Unit
    mg
    Description 
    Thiopropamine
Source: SubstanceSearch (substancesearch.com)

Oral dose (mg): light 20-50 · common 50-100 · strong 100-125 · heavy 125+

Oral duration: onset 15-45m · peak 1-4h · after-effects 1-3h

Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 75 mg (Oral).

    The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.

    Tolerance

    Build-up develops over days to weeks of regular use
    Reset 3–7 days for acute tolerance; longer for full reset

    Tolerance Decay

    Full tolerance 1d Half tolerance 10d Baseline ~18d

    Effects

    Positive
    • Stimulation
    • Physical euphoria
    • Muscle relaxation
    Negative
    • Increased heart rate
    • Nausea
    • Vasoconstriction
    • Respiratory depression
    • Teeth grinding
    • Insomnia
    Neutral
    • Sedation
    Positive
    • Alertness enhancement
    • Cognitive euphoria
    • Euphoria
    • Anxiety suppression
    • Wakefulness
    Negative
    • Anxiety
    • Compulsive redosing
    • Dizziness
    Neutral
    • Talkativeness
    • Time distortion
    Positive
    • Increased music appreciation
    • Increased libido
    • Tactile enhancement
    • Color enhancement
    Negative
    • Light sensitivity
    • Disinhibition
    • Appetite suppression
    • Dehydration
    • Double vision
    Neutral
    • Dulled perception
    Thiopropamine's nerd page Pharmacology, chemical data, effect profiles, and more
    →

    Helpful Links

    📘 Experience Reports 📖 TripSit 📖 PsychonautWiki