Thiopropamine Stats & Data
CC(N)Cc1cccs1NYVQQTOGYLBBDQ-UHFFFAOYSA-NHistory & Culture
Thiopropamine was first synthesized in 1942, though it remained obscure for over seven decades before entering the recreational drug market. The compound only emerged commercially in early 2016, appearing shortly after regulatory action was taken against the structurally related substance MPA (methiopropamine) in the United Kingdom. The timing of thiopropamine's market entry proved historically unfavorable, arriving just weeks before broader legislative changes would restrict its commercial availability. As a result, the substance is generally regarded as a minor footnote in the history of novel psychoactive substances, having entered the scene too late to establish significant cultural presence during the final period of the legal high era.
Effect Profile
CuratedStrong anxiety/jitters and euphoria with moderate stimulation
Tolerance & Pharmacokinetics
drugs.wikiTolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Legal Status
| Country | Status | Notes |
|---|---|---|
| United Kingdom | Psychoactive Substances Act 2016 | Sale and import became prohibited following the implementation of the Psychoactive Substances Act in May 2016. Notably, personal possession is not criminalized under this legislation. Thiopropamine appeared on the UK market in early 2016, shortly before the Act came into force. |