U-47700 - Substance Search

Summary dose.wiki TripSit PsychonautWiki

U-47700 is an extremely dangerous synthetic opioid with approximately 7.5 times the potency of morphine and very little history of human use. It is uniquely caustic to mucous membranes and can cause severe tissue damage with insufflated, sublingual, or smoked administration. A laboratory-grade milligram scale is absolutely essential as sub-milligram differences can mean the difference between an active dose and fatal overdose.

Dose Information dose.wiki TripSit PsychonautWiki

ROA	Light	Common	Strong	Heavy
Oral	5-7.5mg	7.5-15mg	15-25mg	25mg+
Insufflated	4-6mg	6-8mg	8-10mg	10mg+

Light Common Strong Heavy

Onset, Duration & After-effects dose.wiki TripSit PsychonautWiki

ROA	Onset	Comeup	Peak	Offset	After Effects	Total
Oral	10-15 min	-	2-3 hrs	2-3 hrs	2-4 hrs	4.17-6.25 hrs
Insufflated	5-15 min	15-20 min	1-2 hrs	1-2 hrs	2-4 hrs	2.33-4.58 hrs
Intravenous	0-1 min	-	30-60 min	30-60 min	1-3 hrs	1-2.02 hrs
Rectal	10-15 min	-	1-2 hrs	1-2 hrs	2-4 hrs	2.17-4.25 hrs

Effect Profile

9 reports

Scores (1–10) curated from multiple sources:

Effect keyword matching from PsychonautWiki catalog
Weighted by importance: core (×3), major (×2), minor (×1)

Full methodology

Opioid 8.0

Intense 8/10

Strong euphoria and pain relief with mild sedation and itching/nausea

Euphoria / Warmth ×3

10

physical euphoria cognitive euphoria euphoria mood lift

Analgesia ×2

8

pain relief analgesia

Sedation / Relaxation ×1

4

sedation dream potentiation

⚠ Itching / Nausea ×1

4

constipation dry mouth

Based on reports from:

Erowid Experience Reports

Add missing routes to PsychonautWiki Journal

The PsychonautWiki Journal app already has U-47700, but its built-in entry only covers Insufflated. Here are the other routes we have data for. You can't edit a built-in substance, but you can add a Custom Unit for any of these routes to log it.

⬇ Download import file Import this file as custom substances and you get "U-47700 (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.

Custom Unit doses

Oralcommon ~ 11.25 mg

Dose & duration (reference)

U-47700: routes the PsychonautWiki Journal app is missing
Source: SubstanceSearch (substancesearch.com)

Oral dose (mg): light 5-7.5 · common 7.5-15 · strong 15-25 · heavy 25+
Intravenous dose (mg): threshold 0.5-1
Rectal dose (mg): threshold 1-2

Oral duration: onset 10-15m · peak 2-3h · offset 2-3h · total 4.17-6.25h · after-effects 2-4h
Intravenous duration: onset 0-1m · peak 0.5-1h · offset 0.5-1h · total 1-2.02h · after-effects 1-3h
Rectal duration: onset 10-15m · peak 1-2h · offset 1-2h · total 2.17-4.25h · after-effects 2-4h

Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

Custom Units carry a single dose per route, so the full ranges live in the reference above. A route's suggested dose is the midpoint of its common range. Ranges are harm-reduction guidance, not a prescription.

Tolerance

Build-up develops within days of regular use; analgesic tolerance faster than respiratory depression tolerance

Reset 7–14 days for partial reset; full reset may take weeks — tolerance loss greatly increases overdose risk

Tolerance Decay

Full tolerance 1d Half tolerance 21d Baseline ~35d

Effects Erowid

Aggregated from 9 Erowid experience reports

Positive Effects 3

Sedation 44.4% 70%

Euphoria 44.4% 70%

Anxiety Suppression 33.3% 70%

Adverse Effects 0

Combinations

Cross-Check U-47700 with another substance

Community Trip Reports

Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

Erowid 7 reports 1 positive 5 neutral 1 cautionary visit

I Would Definitely Rather Be Safe Than Sorry cautionary exp #110030

My First Date With U-47700 Background: I am a physically fit, 5'11', 220lb male. I have had experience with many drugs in the past, particularly fond of opiates, but being recently subjected to random UA's as a result of pre-trial bond release, options are slim in that area.

Similar to Tramadol positive exp #106314

To start off, I've had experience with a wide variety of psychoactive substances ranging from the hardest of psychedelics like DMT, LSD, 60x Salvia to the bliss of opioids like Opium (tea), Tramadol, Oxycodone, and just about everything in-between.

As a Replacement Opiate neutral exp #108023

I would like to share my experience since there is not much out there pertaining to U-47700. The day I ordered this substance I was not sure how much to get because I didn't know if this was going to be something I was just trying or something I was going to use on a daily basis.

Low Dose Trial Run neutral exp #104912

As there was no real info on dosing I started very low. This is my first low dose experiment. I have no tolerance or dependance to opioids. I have used several types before (heroin, morphine, codeine, opium, Hydromorphone, Oxycodone) but non regularly.

Tachyphylaxis and Other Peculiar Phenomena neutral exp #109396

I've written about U-4 before , but I thought I'd like to make a note about some very peculiar phenomena I've noticed after further experimentation. First, this drug shows remarkable tachyphylaxis (a special kind of rapid 'tolerance' to a drug).

Six or Seven Milligrams Was Good for Me neutral exp #108167

Relaxing with U-47700 Yesterday, I was bored and decided to experiment with some U-47700 for the first time. It is a synthetic opiate, or at least mimics one. I poured saline solution into a 30 ml nasal spray bottle. Then, I weighed 300 mg of U-47700.

An Evening with U-4 neutral exp #108210

Introduction/Caution: This substance is a strong opioid and should be treated with the proper respect. It has been said it is 7.5x more potent than morphine, so a dose of as little as 25 or 30 mg could hypothetically be lethal to an opiate-sensitive person.

Bluelight 2 threads 2 neutral visit

Mdxa First Time Pink Diamonds neutral

this happend a long time ago so sice im a lazzy ass this is the first time i try to document it i cant remember the exact times of events, all i can remember is that time wasnt going normaly one hour would pass in a matter of minnets, he he, and another would go so slowwww, i hope u can understand what im wrighting sin...

U 47700 5 20mg Iv Very Experienced Hell Of A Drug neutral

man this little drug is basically like hydromorphone. Pure as hell, just dissolve in water and into the vein it goes. I've gone through 4 grams or so and yes it is horribly addicting. Brief overview of experience.

U-47700's nerd page Pharmacology, chemical data, effect profiles, and more

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Helpful Links

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U-47700 Well-documented Well-documented Multiple authoritative sources agree on dosing and effects. 4 corroborating sources 2 ROAs with full dose ladders duration data present 19 combo interactions documented toxicity data (PsychonautWiki) classified Research-chemical