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    Vigabatrin Limited data
    Limited data
    Sparse data. Doses and effects may be unreliable or untested.
    • 1 source
    • no dose data
    • PubChem toxicity data

    Summary

    Vigabatrin is an antiepileptic (anticonvulsant) medication, sold under the brand name Sabril. It irreversibly inhibits GABA transaminase, raising brain GABA levels, and is used to treat refractory complex partial seizures and infantile spasms. It is not a recreational drug; long-term use carries a risk of permanent peripheral vision loss.

    Tolerance

    Build-up develops over 1–4 weeks of regular use
    Reset days to weeks depending on duration of use

    Tolerance Decay

    Full tolerance 3d Half tolerance 8d Baseline ~14d

    Effects

    Positive
    • Physical euphoria
    • Muscle relaxation
    • Anxiolytic
    Negative
    • Motor impairment
    • Nausea
    • Respiratory depression
    Neutral
    • Sedation
    • Sedative
    • Dystaxia
    • Itchiness
    Positive
    • Reduced anxiety
    • Cognitive euphoria
    • Anxiety suppression
    • Euphoria
    Negative
    • Dizziness
    • Compulsive redosing
    • Thought deceleration
    • Amnesia
    • Motor control loss
    • Constipation
    Positive
    • Increased music appreciation
    • Increased libido
    Negative
    • Disinhibition
    • Appetite suppression
    • Dehydration
    • Light sensitivity
    • Double vision
    • Acuity suppression
    Neutral
    • Dulled perception
    • Internal hallucinations

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