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    Ziprasidone Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 1 source
    • 2 ROAs with full dose ladders
    • duration data present
    • PubChem toxicity data
    • dose data not in PW/TripSit (unverifiable)

    Aliases: Geodon, Zeldox, Zipwell

    Summary TheDrug.Wiki

    Oral bioavailability doubles when taken with food; dosing on an empty stomach delivers only ~36% of the intended exposure, leading users to redose unnecessarily. Therapeutic QTc prolongation averages 10-20 msec, but heavy recreational doses (>160 mg/day) or IV diversion markedly increases torsade risk. IM ziprasidone reaches Cmax within 60 minutes and has a 2-5 hour half-life, making it a common ER 'trip-stopper'.

    Dose Information TheDrug.Wiki

    ROA Light Common Strong Heavy
    Oral 10-40mg 40-80mg 80-120mg 120mg+
    Intramuscular 5-10mg 10-20mg 20-40mg 40mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki

    ROA Onset Peak Offset After Effects Total
    Oral 1-3 hrs 3-6 hrs 2-4 hrs 6-24 hrs 6-12 hrs
    Intramuscular - 3-6 hrs 2-4 hrs 6-24 hrs 6-12 hrs

    Tolerance

    Build-up develops over 1–4 weeks of regular use
    Reset days to weeks depending on duration of use

    Tolerance Decay

    Half tolerance 3d Baseline ~14d

    Sedative tolerance commonly develops over ~5–7 consecutive nights and recedes over 1–2 weeks off; antipsychotic efficacy tolerance is not a standard concept, but sedation/EPS sensitivity changes with exposure.

    Effects TheDrug.Wiki

    Positive
    • Stimulation
    • Physical Euphoria
    • Pain Relief
    Negative
    • Akathisia
    • Restlessness
    • Motor impairment
    • Sweating
    Neutral
    • Sedation
    • Somnolence
    • Itchiness
    Positive
    • Anxiety suppression
    • Reduced anxiety
    • Euphoria
    Negative
    • Emotion suppression
    • Motivation suppression
    • Motor control loss
    • Cognitive fatigue
    • Dizziness
    • Thought deceleration
    • Constipation
    Negative
    • Light sensitivity
    • Disinhibition
    • Appetite Suppression
    • Decreased Libido
    • Orgasm Suppression
    • Acuity Suppression
    • Appetite suppression
    Neutral
    • Dulled perception
    • Increased sexuality
    • Visual and auditory hallucinations

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.

    Erowid 2 reports 2 neutral visit
    Only for People That Need It neutral exp #68500

    Well I had a drug problem which landed me in jail. I spent 7 months in the county jail and was not done with drugs just yet so I would take whatever guys on prescription meds would get. Anyway we had this kid that would get up off his bunk and inch forward bent over about 5-10 feet here and there at odd times.

    Greg F · Ziprasidone (Geodon) · 1 capsl oral / 1 capsl oral
    What's Is This Shit? neutral exp #53794

    I recently started taking geodon. Almost 15 minutes after I popped my fist pill I felt the effects. There was tingling feeling in my arm and legs. When I sat down my feet wanted to move. It felt great. I couldn't stop smiling and I was laughing at serious things that are not funny.

    Greg · Ziprasidone (Geodon) · 20 mg oral / oral / oral / oral

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