Well I had a drug problem which landed me in jail. I spent 7 months in the county jail and was not done with drugs just yet so I would take whatever guys on prescription meds would get. Anyway we had this kid that would get up off his bunk and inch forward bent over about 5-10 feet here and there at odd times.
Ziprasidone
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 2 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- PubChem toxicity data
- dose data not in PW/TripSit (unverifiable)
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 2 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- PubChem toxicity data
- dose data not in PW/TripSit (unverifiable)
Aliases: Geodon, Zeldox, Zipwell
Summary
Oral bioavailability doubles when taken with food; dosing on an empty stomach delivers only ~36% of the intended exposure, leading users to redose unnecessarily. Therapeutic QTc prolongation averages 10-20 msec, but heavy recreational doses (>160 mg/day) or IV diversion markedly increases torsade risk. IM ziprasidone reaches Cmax within 60 minutes and has a 2-5 hour half-life, making it a common ER 'trip-stopper'.
Dose Information
Dose basis. Take with a meal of at least ~500 kcal; fasting or low‑calorie meals (≈250 kcal) reduce exposure by ~60–90% vs ≥500 kcal meals and can lead to unpredictable underdosing and compensatory redosing. Fat content is not the key determinant; total calories are. Splitting doses BID with food improves exposure consistency. Evidence is from randomized PK studies and sequential food‑effect trials. For acute agitation only; deep IM use, not IV. Contains sulfobutylether β‑cyclodextrin (SBECD); use caution in significant renal impairment. Typical dosing 10–20 mg per injection; max 40 mg/day (e.g., 10 mg q2h or 20 mg q4h). Avoid combining IM with oral ziprasidone and avoid IV administration. Tmax ≈ 60 min; mean IM t1/2 ≈ 2–5 h. (Dose figures and this note are from Drugs.Wiki.)
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 10-40mg | 40-80mg | 80-120mg | 120mg+ |
| Intramuscular | 5-10mg | 10-20mg | 20-40mg | 40mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 1-3 hrs | 1-2 hrs | 3-6 hrs | 2-4 hrs | 7-15 hrs |
| Intramuscular | 15-30 min | 30-60 min | 30-90 min | 2-4 hrs | 3.25-7 hrs |
Add to PsychonautWiki Journal
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Import this file as custom substances
and you get "Ziprasidone (Substance Search)" with every
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versions.
Name
Ziprasidone
Unit
mg
Description
Ziprasidone Source: SubstanceSearch (substancesearch.com) Oral dose (mg): threshold 10 · light 10-40 · common 40-80 · strong 80-120 · heavy 120+ Intramuscular dose (mg): threshold 5 · light 5-10 · common 10-20 · strong 20-40 · heavy 40+ Oral duration: onset 1-3h · come-up 1-2h · peak 3-6h · offset 2-4h · total 7-15h · after-effects 6-24h Intramuscular duration: onset 15-30m · come-up 0.5-1h · peak 0.5-1.5h · offset 2-4h · total 3.25-7h · after-effects 6-24h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 60 mg (Oral).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Build-up
develops over 1–4 weeks of regular use
Reset
days to weeks depending on duration of use
Tolerance Decay
Half tolerance
3d
Baseline
~14d
Sedative tolerance commonly develops over ~5–7 consecutive nights and recedes over 1–2 weeks off; antipsychotic efficacy tolerance is not a standard concept, but sedation/EPS sensitivity changes with exposure.
Effects
Positive
- Stimulation
- Physical Euphoria
- Pain Relief
Negative
- Akathisia
- Restlessness
- Motor impairment
- Sweating
- Sedation
- Somnolence
- Itchiness
Positive
- Anxiety suppression
- Reduced anxiety
- Euphoria
Negative
- Emotion suppression
- Motivation suppression
- Motor control loss
- Cognitive fatigue
- Dizziness
- Thought deceleration
- Constipation
Negative
- Light sensitivity
- Disinhibition
- Appetite Suppression
- Decreased Libido
- Orgasm Suppression
- Acuity Suppression
- Dulled perception
- Increased sexuality
- Visual and auditory hallucinations
Community Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.
Erowid 2 reports 1 neutral 1 cautionary visit
I recently started taking geodon. Almost 15 minutes after I popped my fist pill I felt the effects. There was tingling feeling in my arm and legs. When I sat down my feet wanted to move. It felt great. I couldn't stop smiling and I was laughing at serious things that are not funny.
Pill Identifiers
16
known pill identifiers on record — view imprints, colors, shapes, and images
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Ziprasidone's nerd page
Pharmacology, chemical data, effect profiles, and more
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Helpful Links
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