25I-NBMD
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 3 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 18 combo interactions documented
- classified Tentative
- classified Research-chemical
- 3 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 18 combo interactions documented
- classified Tentative
- classified Research-chemical
Aliases: Cimbi-29, Nbmd-2c-i
Summary
25I-NBMD is a highly potent benzylated phenethylamine with a 2,3-methylenedioxy group on the N-benzyl moiety, differing structurally from NBOMe analogues. Sub-milligram accuracy is essential; use a 0.001 mg analytical balance and volumetric dosing. Vasoconstriction, tachycardia, and peripheral numbness are commonly reported.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Sublingual | 800-1500ug | 1500-2000ug | 2000-3000ug | 3000ug+ |
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Sublingual | 15-40 min | 30-60 min | 1-3 hrs | 2-4 hrs | 4-6 hrs |
| Insufflated | 5-20 min | 20-40 min | 1-3 hrs | 2-4 hrs | 4-6 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong visuals with moderate auditory effects and body load, mild headspace
Add to PsychonautWiki Journal
The PsychonautWiki Journal logging app doesn't include every substance. To track 25I-NBMD there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:
25I-NBMD Source: SubstanceSearch (substancesearch.com) Sublingual dose (µg): light 800-1500ug · common 1500-2000ug · strong 2000-3000ug · heavy 3000ug+ Insufflated dose (µg): threshold 150-300ug Sublingual duration: onset 15-40m · come-up 0.5-1h · peak 1-3h · offset 2-4h · total 4-6h · after-effects 1-8h Insufflated duration: onset 5-20m · come-up 20-40m · peak 1-3h · offset 2-4h · total 4-6h · after-effects 1-8h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 1750 µg (Sublingual).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Tolerance Decay
Rapid cross-tolerance with other 5‑HT2A psychedelics is expected; conservative spacing of ≥10–14 days between experiences helps restore baseline sensitivity. Data are anecdotal due to limited human studies.
Cross-Tolerances
Effects
- Stimulation
- Physical euphoria
- Vasoconstriction
- Increased heart rate
- Nausea
- Pupil dilation
- Insomnia
- Mouth numbing
- Dilated pupils
- Sedation
- Euphoria
- Synesthesia
- Conceptual thinking
- Analysis enhancement
- Anxiety
- Confusion
- Memory suppression
- Motor control loss
- Time distortion
- Thought acceleration
- Color enhancement
- Color shifting
- Pattern recognition enhancement
- Bodily lightness
- Tactile enhancement
- Tracers
- Drifting
- Symmetrical texture repetition
- Spontaneous physical sensations
- Auditory distortion
Combinations
Cross-Check 25I-NBMD with another substanceHelpful Links
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