Summary
25I-NBMD is a highly potent benzylated phenethylamine with a 2,3-methylenedioxy group on the N-benzyl moiety, differing structurally from NBOMe analogues. Sub-milligram accuracy is essential; use a 0.001 mg analytical balance and volumetric dosing. Vasoconstriction, tachycardia, and peripheral numbness are commonly reported. Serious incidents with the NBOMe/NBMD family include hyperthermia, rhabdomyolysis, seizures, and fatal overdoses - almost always from mis-weighed doses or insufflation. Never insufflate this compound.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Sublingual | 800-1500ug | 1500-2000ug | 2000-3000ug | 3000ug+ |
| Buccal | 800-1500ug | 1500-2000ug | 2000-3000ug | 3000µg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects | Total |
|---|---|---|---|---|---|---|
| Sublingual | 15-40 min | 30-60 min | 1-3 hrs | 2-4 hrs | 1-8 hrs | 240-0 min |
| Buccal | 15-40 min | 30-60 min | 1-3 hrs | 2-4 hrs | 1-8 hrs | 240-0 min |
| Insufflated | 5-20 min | 20-40 min | 1-3 hrs | 2-4 hrs | 1-8 hrs | 240-0 min |
Tolerance
Build-up
develops rapidly after a single use (serotonergic psychedelic)
Reset
7–14 days for baseline
Effects
Positive
- Stimulation
- Physical euphoria
Negative
- Vasoconstriction
- Increased heart rate
- Nausea
- Pupil dilation
- Insomnia
- Mouth numbing
- Dilated pupils
- Sedation
Positive
- Euphoria
- Synesthesia
- Conceptual thinking
- Analysis enhancement
Negative
- Anxiety
- Confusion
- Memory suppression
- Motor control loss
- Time distortion
- Thought acceleration
Positive
- Color enhancement
- Color shifting
- Pattern recognition enhancement
- Bodily lightness
- Tactile enhancement
- Tracers
Negative
- Drifting
- Symmetrical texture repetition
- Spontaneous physical sensations
- Auditory distortion