25iP-NBOMe
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 3 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 19 combo interactions documented
- classified Tentative
- classified Research-chemical
- 3 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 19 combo interactions documented
- classified Tentative
- classified Research-chemical
Aliases: 25ip, 2c-ip-nbome, Nbome-2c-ip
Summary
25iP-NBOMe is extremely potent and dangerous. NBOMes have been associated with numerous deaths and hospitalizations at doses that users believed to be safe. Always use a 0.001 g analytical scale or volumetric dosing for accuracy.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Intranasal | - | - | - | 900ug+ (high risk) |
| Oral | - | - | - | 2500 ug+ (unpredictable) |
| Sublingual | 300-750ug | 750-1000ug | 1000-1500ug | 1500ug+ |
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Intranasal | 5-15 min | 15-30 min | 2-4 hrs | 2-3 hrs | 5-7 hrs |
| Oral | 45-90 min | 60-90 min | 2-4 hrs | 2-3 hrs | 5-7 hrs |
| Sublingual | 30-60 min | - | 5-7 hrs | - | 5-7 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong visuals and body load with mild auditory effects, low headspace
Strong anxiety/jitters with moderate euphoria, low stimulation
Add to PsychonautWiki Journal
The PsychonautWiki Journal logging app doesn't include every substance. To track 25iP-NBOMe there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:
25iP-NBOMe Source: SubstanceSearch (substancesearch.com) Intranasal dose (µg): threshold 75-150ug · heavy 900ug+ (high risk) Oral dose (µg): threshold 500-700ug · heavy 2500 ug+ (unpredictable) Sublingual dose (µg): threshold 250ug · light 300-750ug · common 750-1000ug · strong 1000-1500ug · heavy 1500ug+ Intranasal duration: onset 5-15m · come-up 15-30m · peak 2-4h · offset 2-3h · total 5-7h · after-effects 6-12h Oral duration: onset 0.75-1.5h · come-up 1-1.5h · peak 2-4h · offset 2-3h · total 5-7h · after-effects 6-12h Sublingual duration: onset 0.5-1h · peak 5-7h · total 5-7h · after-effects 1-12h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 875 µg (Sublingual).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Tolerance Decay
Acute tolerance develops rapidly after a single strong session (typical of 5‑HT2A agonists). Substantial tolerance persists for days and decays over 1–3+ weeks; precise kinetics for 25iP‑NBOMe are not characterized. Cross‑tolerance with other psychedelics is expected but unquantified; ratios are heuristic. Data quality relies on class‑level evidence and user reports, not controlled human studies.
Cross-Tolerances
Effects
- Stimulation
- Physical Euphoria
- Mental/physical stimulation
- Vasoconstriction
- Increased Heart Rate
- Increased Blood Pressure
- Muscle Tension
- Nausea
- Temperature Regulation Suppression
- Teeth Grinding
- Insomnia
- Pupil dilation
- Restlessness
- Sweating/chills
- Difficulty Urinating
- Decreased appetite
- Euphoria
- Empathy Enhancement
- Empathy
- Insight
- Anxiety
- Confusion
- Thought Loops
- Time Distortion
- Change in perception
- Ego softening
- Visual Geometry
- Color Enhancement
- Pattern Recognition Enhancement
- Acuity Enhancement
- Tracers
- Tactile Enhancement
- Bodily Control Enhancement
- Brightened colour
- Enhanced tactile sensation
- Drifting
- After Images
- Symmetrical Texture Repetition
- Scenery Slicing
- Internal Hallucinations
- Auditory Distortion
- Closed/Open eye visuals
Combinations
Cross-Check 25iP-NBOMe with another substanceHelpful Links
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