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    Disclaimer
    ☠ This substance has been associated with serious adverse events including fatalities. Use extreme caution.
    ☢ This substance has an extremely narrow safety margin. Small dosing errors can lead to life-threatening effects.
    ☠ NBOMe compounds are active at sub-milligram doses and have been linked to numerous deaths. They are frequently mis-sold as LSD. Always test substances before use.
    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    25T-2-NBOMe

    Aliases: N-bomb, 2c-t-2-nbome, 25t2-nbome

    Psychedelic Research-chemical

    Summary TheDrug.Wiki TripSit

    25T-2-NBOMe is a highly potent NBOMe derivative active in the microgram range. This compound is the N-(2-methoxybenzyl) derivative of 2C-T-2 and exhibits significantly increased potency compared to its parent compound. Accurate measurement with a 0.001 g (milligram) scale or volumetric dosing is essential; visual dosing is extremely dangerous and responsible for most NBOMe hospitalisations and fatalities.

    Dose Information TheDrug.Wiki TripSit

    ROA Light Common Strong Heavy
    Sublingual 100-300ug 300-600ug 600-1000ug 1000ug+
    Buccal 100-300ug 300-600ug 600-1000ug 1000µg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit

    ROA Onset Comeup Peak Offset After Effects Total
    Sublingual 15-45 min 30-60 min 1-3 hrs 3-6 hrs 2-10 hrs 4.8-10.8 hrs
    Buccal 15-45 min 30-60 min 1-3 hrs 3-6 hrs 2-10 hrs 4.8-10.8 hrs
    Insufflated 5-15 min 15-30 min 1-3 hrs 3-6 hrs 2-10 hrs 4.3-9.8 hrs

    Effect Profile

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 6.4
    Strong 6/10

    Strong visuals and body load with moderate auditory effects, mild headspace

    Visual Intensity ×3
    10
    visual geometry colour enhancement synesthesia drifting tracers visual enhancement +1 more
    Headspace Depth ×3
    4
    conceptual thinking time distortion confusion
    Auditory Effects ×1
    7
    auditory distortion synesthesia
    ⚠ Body Load / Somatic Effects ×1
    8
    vasoconstriction nausea temperature regulation suppression increased heart rate
    Based on reports from:
    Erowid Experience Reports PsychonautWiki 25T-2-NBOMe
    View methodology →

    Tolerance

    Build-up develops rapidly after a single use (serotonergic psychedelic)
    Reset 7–14 days for baseline

    Tolerance Decay

    Full tolerance 1d Half tolerance 3d Baseline ~7d

    Cross-tolerance likely with other 5-HT2A psychedelics. Rapid acute tolerance after one session; partial tolerance may persist for about a week. Values are approximate and based on community/series reports rather than controlled studies.

    Cross-Tolerances

    LSD
    70%
    Psilocybin
    60%
    2C-x phenethylamines
    50%
    Other NBOMes
    90%

    Effects TheDrug.Wiki

    Positive
    • Stimulation
    • Physical euphoria
    Negative
    • Vasoconstriction
    • Nausea
    • Increased heart rate
    • Temperature regulation suppression
    • Pupil dilation
    • Insomnia
    Neutral
    • Mouth numbing
    • Sedation
    Positive
    • Mild euphoria
    • Synesthesia
    • Analysis enhancement
    • Euphoria
    • Conceptual thinking
    Negative
    • Anxiety
    • Confusion
    • Memory suppression
    • Motor control loss
    Neutral
    • Time distortion
    Positive
    • Visual enhancement
    • Colour enhancement
    • Pattern recognition enhancement
    • Visual geometry
    • Tracers
    • Tactile enhancement
    • Color enhancement
    • Increased music appreciation
    Neutral
    • Drifting
    • Auditory distortion

    Combinations TripSit

    25T-2-NBOMe's nerd page Pharmacology, chemical data, effect profiles, and more
    →

    Helpful Links

    📘 Experience Reports 📖 TheDrug.Wiki 📖 TripSit 📖 PsychonautWiki