2C-B
Aliases: Bees, Erox, Nexus, Venus, Bdmpea, 2cb, 2-cb
Summary
4-Bromo-2,5-dimethoxyphenethylamine (also known as Nexus, Bromo Mescaline, BDMPEA, Venus, and 2C-B) is a novel psychedelic substance of the phenethylamine class. It is perhaps the most well-known member of the 2C-x family, which are structurally related to the classical psychedelic mescaline. The mechanism of action is not fully known, although serotonin receptor binding activity is thought to be principally involved.
Perspectives
“2C-B remains one of those substances that defies easy categorization—simultaneously stimulating and relaxing, visual yet lucid, euphoric yet manageable.”
“A day at the Stanford museum. Things were visually rich, yet I felt that I was reasonably inconspicuous. The Rodin sculptures were very personal and not terribly subtle. I saw Escher things in the ceiling design, when I decided to sit in a foyer somewhere and simply pretend to rest. Walking back, the displays seen in the bark of the eucalyptus trees, and the torment and fear (of others? of themselves?) in the faces of those who were walking towards us, were as dramatic as anything I had seen in the art galleries. Our appetites were enormous, and we went to a smorgasbord that evening. A rich experience in every possible way.”
“Overall, this was a good experience. I can see how some people confuse it with MDMA, but I found it to be less empathogenic and I was much more body conscious.”
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral BA ~70% | 10-15mg | 15-25mg | 25-45mg | 45mg+ |
| Insufflated BA ~75% | 5-8mg | 8-12mg | 12-23mg | 23mg+ |
| Rectal | 5-8mg | 8-12mg | 12-23mg | 23mg+ |
| Intravenous | 1-2.5mg | 2.5-5mg | 5-10mg | 10mg+ |
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 19-45 min | 45-90 min | 2-4 hrs | 1-2 hrs | 4-8 hrs |
| Insufflated | 1-10 min | 10-19 min | 2-3 hrs | 1-2 hrs | - |
| Rectal | 4-19 min | 19-40 min | 2-4 hrs | 1-2 hrs | - |
Effect Profile
536 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Validated against 394 Erowid trip reports
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong visuals with moderate auditory effects, mild body load and headspace
“During meditation, visual distortions manifested themselves as visual drifting (breathing) of the walls, color shifting, and the symmetrical texture repetition of abstract imagery (eyes and shrooms...”
“There are very few closed eye visuals- they mostly present with my eyes open.”
“As I smoked, I was able to experience conceptual thinking about the cigarette in my hand.”
“I did not want to be introspective or judging myself, I have realized and learnt in the past, from my past experience with ego death, that in essence I struggle with believing positive things about...”
“2cb is really one of a kind with its cartoony visuals and signature body high and music enhancement yet sociability.”
“The walk was filled with manicured trees and flowers and the idle sounds of distant lawnmowers and dogs barking and birdsongs, the soundtrack of the living breathing suburb.”
“I am stricken with nasty nausea and discomfort, along with intense sweating.”
“I was hit by a sudden wave of nausea at T+1:00.”
User Experience
Strong sensory enhancement with mild euphoria and stimulation, low empathy
“I enjoyed the empathogenic properties of increased empathy and sociability.”
“got a new love for this drug.”
“They had a large property with a beautiful pool and garden, and it was in a textbook idyllic suburb on an incredible sunny summer day.”
“I have used DXM multiple times before at mid-second plat, and once at first plat with a (0.5g cubes) shroom combo (which was incredible).”
“In that situation it should best be taken with someone with experience, and someone whose energy is there to guide you through the experience, someone whose energy seeks to guide your mood to a...”
“Instead of some sort of energy or vibrations, I just felt physically very tired.”
“The purpose of this trip was to reduce my current Post-Traumatic Stress Disorder symptoms from a sexual assault that occurred a year ago.”
“I listened to music, looked at nature, and enjoyed the sun on my skin.”
User Experience
Tolerance
Tolerance Decay
Psychedelic tolerance is marked after one session and tends to return close to baseline within 1–2 weeks; spacing experiences by at least 2 weeks is common HR advice.
Cross-Tolerances
Effects
Aggregated from 394 Erowid and 142 Bluelight experience reports
Positive Effects 73
Adverse Effects 46
Combinations
Trip Reports
PiHKAL / TiHKAL
“A day at the Stanford museum. Things were visually rich, yet I felt that I was reasonably inconspicuous. The Rodin sculptures were very personal and not terribly subtle. I saw Escher things in the ceiling design, when I decided to sit in a foyer somewhere and simply pretend to rest. Walking back, the displays seen in the bark of the eucalyptus trees, and the torment and fear (of others? of themselves?) in the faces of those who were walking towards us, were as dramatic as anything I had seen in the art galleries. Our appetites were enormous, and we went to a smorgasbord that evening. A rich experience in every possible way.”