Home
    Disclaimer
    πŸ§ͺ This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    2C-B Well-documented
    Well-documented
    Multiple authoritative sources agree on dosing and effects.
    • 7 corroborating sources
    • 4 ROAs with full dose ladders
    • duration data present
    • 18 combo interactions documented
    • PubChem toxicity data
    • classified Research-chemical

    Aliases: Bees, Erox, Nexus, Venus, Bdmpea, 2cb, 2-cb

    Summary TheDrug.Wiki Erowid TripSit PsychonautWiki

    4-Bromo-2,5-dimethoxyphenethylamine (also known as Nexus, Bromo Mescaline, BDMPEA, Venus, and 2C-B) is a novel psychedelic substance of the phenethylamine class. It is perhaps the most well-known member of the 2C-x family, which are structurally related to the classical psychedelic mescaline. The mechanism of action is not fully known, although serotonin receptor binding activity is thought to be principally involved.

    Perspectives

    “2C-B remains one of those substances that defies easy categorizationβ€”simultaneously stimulating and relaxing, visual yet lucid, euphoric yet manageable.”

    “A day at the Stanford museum. Things were visually rich, yet I felt that I was reasonably inconspicuous. The Rodin sculptures were very personal and not terribly subtle. I saw Escher things in the ceiling design, when I decided to sit in a foyer somewhere and simply pretend to rest. Walking back, the displays seen in the bark of the eucalyptus trees, and the torment and fear (of others? of themselves?) in the faces of those who were walking towards us, were as dramatic as anything I had seen in the art galleries. Our appetites were enormous, and we went to a smorgasbord that evening. A rich experience in every possible way.”

    “Overall, this was a good experience. I can see how some people confuse it with MDMA, but I found it to be less empathogenic and I was much more body conscious.”

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral BA ~70% 10-15mg 15-25mg 25-45mg 45mg+
    Insufflated BA ~75% 5-8mg 8-12mg 12-23mg 23mg+
    Rectal 5-8mg 8-12mg 12-23mg 23mg+
    Intravenous 1-2.5mg 2.5-5mg 5-10mg 10mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 19-45 min 45-90 min 2-4 hrs 1-2 hrs 2-4 hrs 4-8 hrs
    Insufflated 1-10 min 10-19 min 2-3 hrs 1-2 hrs 2-4 hrs -
    Rectal 4-19 min 19-40 min 2-4 hrs 1-2 hrs 2-4 hrs -
    Intravenous - - 12-30 min 1.5-2 hrs 2-4 hrs -

    Effect Profile

    536 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Validated against 394 Erowid trip reports
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 5.9
    Strong 6/10

    Strong visuals with moderate auditory effects, mild body load and headspace

    Visual Intensity ×3
    8
    internal hallucinations color enhancement autonomous entities tracers drifting synaesthesia +8 more

    “During meditation, visual distortions manifested themselves as visual drifting (breathing) of the walls, color shifting, and the symmetrical texture repetition of abstract imagery (eyes and shrooms...”

    Oscarette effectindex

    “There are very few closed eye visuals- they mostly present with my eyes open.”

    nervewing effectindex
    Headspace Depth ×3
    4
    conceptual thinking thought connectivity feelings of interdependent opposites recursion emotion enhancement feelings of self-design +5 more

    “As I smoked, I was able to experience conceptual thinking about the cigarette in my hand.”

    Oscarette effectindex

    “I did not want to be introspective or judging myself, I have realized and learnt in the past, from my past experience with ego death, that in essence I struggle with believing positive things about...”

    LeftoverNinja effectindex
    Auditory Effects ×1
    6
    auditory distortion auditory enhancement auditory hallucinations auditory hallucination synaesthesia

    “2cb is really one of a kind with its cartoony visuals and signature body high and music enhancement yet sociability.”

    SONN bluelight

    “The walk was filled with manicured trees and flowers and the idle sounds of distant lawnmowers and dogs barking and birdsongs, the soundtrack of the living breathing suburb.”

    nervewing effectindex
    Body Load / Somatic Effects ×1
    5
    nausea muscle tension teeth grinding increased heart rate

    “I am stricken with nasty nausea and discomfort, along with intense sweating.”

    nervewing effectindex

    “I was hit by a sudden wave of nausea at T+1:00.”

    Oscarette effectindex

    User Experience

    visuals “During meditation, visual distortions manifested themselves as visual drifting (breathing) of the walls, color shifting, and the symmetrical texture repetition of abstract imagery (eyes and shrooms...” — Oscarette, effectindex
    Empathogen 4.4
    Moderate 4/10

    Strong sensory enhancement with mild euphoria and stimulation, low empathy

    Empathy / Social Openness ×3
    3
    empathy enhancement empathy empathy, love, and sociability enhancement empathy, affection and sociability enhancement

    “I enjoyed the empathogenic properties of increased empathy and sociability.”

    Oscarette effectindex

    “got a new love for this drug.”

    i against i bluelight
    Euphoria / Mood Elevation ×2
    5
    physical euphoria euphoria emotion enhancement

    “They had a large property with a beautiful pool and garden, and it was in a textbook idyllic suburb on an incredible sunny summer day.”

    nervewing effectindex

    “I have used DXM multiple times before at mid-second plat, and once at first plat with a (0.5g cubes) shroom combo (which was incredible).”

    LeftoverNinja effectindex
    Stimulation ×1
    4
    stimulation wakefulness restlessness teeth grinding increased heart rate

    “In that situation it should best be taken with someone with experience, and someone whose energy is there to guide you through the experience, someone whose energy seeks to guide your mood to a...”

    omicamushroom bluelight

    “Instead of some sort of energy or vibrations, I just felt physically very tired.”

    0x00 bluelight
    Sensory Enhancement ×1
    8
    tactile enhancement enhanced tactile sensation spontaneous tactile sensations color enhancement acuity enhancement visual acuity enhancement +1 more

    “The purpose of this trip was to reduce my current Post-Traumatic Stress Disorder symptoms from a sexual assault that occurred a year ago.”

    Oscarette effectindex

    “I listened to music, looked at nature, and enjoyed the sun on my skin.”

    LeftoverNinja effectindex

    User Experience

    sensory enhancement “The purpose of this trip was to reduce my current Post-Traumatic Stress Disorder symptoms from a sexual assault that occurred a year ago.” — Oscarette, effectindex

    Tolerance

    Build-up develops rapidly after a single use
    Reset 7–14 days for baseline

    Tolerance Decay

    Half tolerance 7d Baseline ~14d

    Psychedelic tolerance is marked after one session and tends to return close to baseline within 1–2 weeks; spacing experiences by at least 2 weeks is common HR advice.

    Cross-Tolerances

    LSD
    50%
    mescaline
    60%

    Effects Erowid Bluelight

    Aggregated from 394 Erowid and 142 Bluelight experience reports

    Positive Effects 73

    Visual Distortions 74.7% 78%
    Color Enhancement 59.9% 86%
    Music Enhancement 50.0% 84%
    Euphoria 47.3% 90%
    Empathy 43.7% 84%
    Stimulation 42.3% 80%
    Surface Breathing 40.0% 84%
    Joy 38.0% 87%
    Sociability Enhancement 38.0% 84%
    Tactile Enhancement 36.2% 84%
    Contentment 30.0% 80%
    Patterning 28.0% 86%
    Awe 28.0% 82%
    Focus Enhancement 27.7% 80%
    Introspection 26.6% 80%
    Closed-Eye Visuals 25.2% 88%
    Auditory Effects 25.0% 82%
    Insight 22.0% 82%
    Morphing 22.0% 86%
    Love 22.0% 85%

    Adverse Effects 46

    Anxiety 45.8% 78%
    Confusion 32.6% 79%
    Nausea 28.6% 86%
    Body Load 16.0% 80%
    Muscle Tension 14.2% 80%
    Fear 14.0% 83%
    Paranoia 12.0% 76%
    Entity Imagery 10.0% 77%
    Depersonalization 10.0% 80%
    Stomach Cramps 10.0% 84%
    Ego Dissolution 9.9% 80%
    Headache 9.0% 80%
    Dry Mouth 8.0% 70%
    Vomiting 8.0% 92%
    Body Temperature Change 8.0% 81%
    Tremor 8.0% 78%
    Thought Loops 7.7% 82%
    Sweating 7.7% 87%
    Jaw Clenching 7.6% 72%
    Increased Heart Rate 6.1% 70%

    Combinations TripSit

    Cross-Check 2C-B with another substance

    Trip Reports Effect Index

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.

    Reddit 8 reports 1 positive 5 neutral 2 cautionary visit
    Had a life changing experience yesterday on 2cb (positive) positive r/2cb ▲24 51 comments

    Hi everyone, Yesterday I decided to pop a pink NASA 2cb rocket (25mg). The first time I did 2cb was nearly 18 years ago so this was the second time and overal I was never really into doing psychs anyways, so I thought it was time to give it a try once again.

    u/Less-Specialist9397 · 2026-04-20
    an orgasm so good im almost concerned neutral r/2cb ▲194 23 comments

    bro. im mad cuz I cant tell anyone irl abt this bc my only drug friends r dudes. and I'm a chick so that's weird. but I took a 15mg 2cb pill by myself a few days ago for the first time.

    u/anonymous · 2024-09-28
    This Molecule Though neutral r/2cb ▲26 6 comments

    Wow! What an amazing experience we shared last night. Started low and slow as this was our first 2C-B trip and now looking forward to the future and exploring more. For all of you who share your experiences on here, thank you.

    u/WJBPhoto · 2026-04-26
    First 2C-B trip. INSANE neutral ▲25 9 comments

    To kick off this tale, I was 17 and deeply immersed in the world of psychedelics and cannabis. My mindset was undeniably experimental, having indulged in acid numerous times at excessively high doses and thoroughly enjoying the experiences.

    u/TheMediator42069 · 2024-03-11
    2G mushroom trip~ I’m curious to know if this has ever happened to anyone else neutral ▲24 18 comments

    I’m currently in Costa Rica and decided to sit with medicine today and I ate a mushroom chocolate with 2.5 g. Unfortunately my stomach did not like that and I puked all of it nearly 20 minutes after I ate it and lost desired effects. I had some mushroom honey, not sure how much.

    u/anonymous · 2023-01-20
    Trying for the first time, how bad is snorting it really? neutral r/2cb ▲5 6 comments

    Hey all, it’s a beautiful spring day today and I have a g of powder that has gone untouched for about a year because I’ve been too anxious to try it… but I think today might be the day! Really I want to try it now because I want to take it at a convention next weekend in lieu of...

    u/shroombadger · 2026-05-03
    My first time on ~50 mg 2C-B: a cautionary tale about weighing your drugs properly cautionary r/tripreports ▲125 9 comments

    I was hanging out with a friend, and she asked if I wanted to try 2CB. She said it was like ecstasy without a comedown, and would only last for 5-6 hours. I was nervous because I had been under a lot of stress, and also because coming up on MDMA is very unpleasant for me.

    u/psilocindream · 2020-09-01
    Crazy nightmare trip cautionary r/2cb ▲12 17 comments

    Popped two 24mg pills and had a really good trip that was super introspective and pleasant, right on the tail end of my comedown I smoked half a joint thinking it wouldn’t be that bad, spent the next 4 hours in the worst trip ever, pure anxiety and visual intensity without any eu...

    u/Joejfad · 2026-04-25
    Erowid 8 reports 3 positive 3 neutral 2 cautionary visit
    Sex With My Ghostly Lover positive exp #110957

    Synopsis: Experienced tripper has his first worthy sexual experience with 2C-B, but only after letting go of desires and expectations and inviting an energetic entity he refers to as his 'ghostly lover'.

    fenugreekfur · 20 mg rectal
    Love Story 2 positive exp #113459

    I had rented a cabin in West Virginia as a birthday present to Sam, hoping to relive the wonderful LSD Β­tinged cabin trip we had taken in January. I still had two 25mg capsules of 2CΒ­B Hbr that I had weighed out the previous weekend and never eaten, so we decided to take those.

    yardbird · 25 mg oral / 0.5 mg oral / vaporized
    Iridescent Pool Party positive exp #109078

    Preface: I could never have imagined a more perfect setting would present itself. My friend was back at his parentΒ’s house in the suburbs, a place familiar to me since I was 6 years old, a place of comfort and pleasant memories.

    nervewing · 30 mg oral
    A High Dose 2C-B Trip neutral exp #10623

    Copyright December 1984 by Gracie and Zarkov Productions. We believe that in a truly free society the price of packaged information would be driven down to the cost of reproduction and transmission.

    Gracie & Zarkov
    It Teaches Me to Be neutral exp #112595

    2C-B Teaches Me to Be 5:25 PM , 18mg 2C-B Will do this in a bit of an odd format, the note followed by my memory of the experience near the note. Seems the most convenient. Took a measured amount 18mg 2C-B hcl, I have an extensive history of psych use in the past include LSD, Al-Lad, 4-ho-mipt, MDMA.

    Waffers · 18 mg oral / 6.6 mg insufflated
    The Shining of the Spectrum neutral exp #63419

    Substance: 2C-B Dose: 25 Milligrams / Yellow MTV Pressed Pill Setting: California Desert during Early-morning/Sunrise. Date: Spring 2004. 12:30 AM. I had been looking for 2C-B for many years prior to this event. Since I learned about it in 9th grade, I had always been interested in this chemical.

    Psilo707 · 25 mg oral
    Accidental Overdose Panic cautionary exp #76578

    I've been meaning to post to this site about this experience since it happened - but initially it was too close, and then having not been so much in that world lately I haven't thought about it.

    Reporter · 120 mg insufflated
    A Visual Spectacular cautionary exp #101038

    I am a first-time 2cb user and the powder is in a capsule so I do not know the exact mass of the substance. However, based off of the trip reports in Pihkal (Shulgin), as well as numerous others, I am going to estimate that each capsule contained 10-15 mg.

    Riley · 1 capsl oral / 1 smoked / 1 capsl oral / 400 mg oral
    Bluelight 8 threads 2 positive 5 neutral 1 cautionary visit
    2c B 25mg Experienced αΌœΟΟ‰Ο‚ Love Story positive

    Date: May 3, 2014 Time: 2:00pm - 6:00pm Drug: 2C-B Hbr Dose: 25mg I had rented a cabin in West Virginia as a birthday present to Sam, hoping to relive the wonderful LSD-tinged cabin trip we had taken in January.

    scraped 2026-03-14
    2c B 25mg Second Time In The End Love Is All What Matters positive

    I haven' t read a lot of trip reports yet. I don't know if somebody wants to make fun out of mine. It was a very personal experience, hard to understand if you're not me, nonetheless so beautiful that I had to share it! My story is very detailed, probably because this is one of my first psychedelics experiences, and I'...

    scraped 2026-03-14
    2c B 17 Mg First Time Dancing Colors And Delightful Music neutral

    This will be my first trip report in a while, its been some time since i last wrote one so bear with me, and excuse my mistakes. Im in my late 20s, with a little over a year of experience with varios substances, a vast majority of them being psychedelics.

    scraped 2026-03-14
    2c B 3rd Time The Puzzle Pieces Of Life Slamming Down Upon Me neutral

    22/04/2004 Set : I have been in another one of these phases where I get too many possible chemicals in my hands, and just go a bit too hard on experimenting. Still trying to find what's missing in life in the wrong ways (by abusing psychedelic drugs).

    scraped 2026-03-14
    2c B First Time The Shining Of The Spectrum neutral

    Substance: 2C-B (4-bromo-2,5-dimethoxyphenethylamine) Dose: ~25 Milligrams / Yellow MTV Pressed Pill Setting: California Desert during Early-morning/Sunrise. Date: Saturday, May 1. 12:30 AM. It's been a couple of months since this experience, and I meant to post this up much earlier, but I enjoy slacking off.

    scraped 2026-03-14
    2c B First Time New World neutral

    This is actually really, really long. I don't know if anyone is actually going to want to read this, but you can just skim through it. I really wanted to write this just so I never forget this experience. Me and my friend had two 25mg capsules of 2c-b.

    scraped 2026-03-14

    Bluelight Reference Guide Bluelight

    Phenethylamines The Big & Dandy 2C-B Thread - Stage 2

    Welcome to the Big & Dandy 2C-B Thread External Information Links Erowid 2C-B Vault (experience reports) PIHKAL Entry on 2C-B Wikipedia entry Drug Text Info on 2C-B Focused Discussion Sub-Threads Please use these threads if you have questions or comments about their specialized topics First Time Dosage and Methods of A...

    Read full thread on Bluelight β†’

    PiHKAL / TiHKAL Shulgin

    PiHKAL #20: 2C-B

    “A day at the Stanford museum. Things were visually rich, yet I felt that I was reasonably inconspicuous. The Rodin sculptures were very personal and not terribly subtle. I saw Escher things in the ceiling design, when I decided to sit in a foyer somewhere and simply pretend to rest. Walking back, the displays seen in the bark of the eucalyptus trees, and the torment and fear (of others? of themselves?) in the faces of those who were walking towards us, were as dramatic as anything I had seen in the art galleries. Our appetites were enormous, and we went to a smorgasbord that evening. A rich experience in every possible way.”

    β€” Alexander Shulgin, PiHKAL (with 16 mg)

    Helpful Links