Summary
Extremely caustic to nasal mucosa; users report intense burn and chronic rhinitis after repeated insufflation. Strong vasoconstriction requires monitoring extremity temperature. Severe hyponatremia reported in prolonged binges; maintain balanced electrolyte intake. In vitro studies suggest neurotoxicity through oxidative stress and autophagy induction, warranting limited frequency and conservative dosing.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 25-50mg | 50-100mg | 100-150mg | 150mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects | Total |
|---|---|---|---|---|---|---|
| Oral | 10-30 min | 15-30 min | 60-90 min | 1-2 hrs | 2-6 hrs | 120-0 min |
| Insufflated | 2-10 min | 5-15 min | 60-90 min | 1-2 hrs | 2-6 hrs | 120-0 min |
| Rectal | 5-20 min | 10-20 min | 60-90 min | 1-2 hrs | 2-6 hrs | 120-0 min |
Tolerance
Build-up
develops rapidly, often within a single session; compulsive redosing common
Reset
a few days for acute tolerance
Effects
Positive
- Stimulation
- Increased energy
- Increased energy/alertness
Negative
- Teeth grinding
- Bruxism
- Sweating
- Insomnia
- Weight loss
- Hyperthermia
- Decreased need for sleep
- Decreased appetite
- Disturbed sleep patterns
- Itchiness
Positive
- Euphoria
- Enhanced sociability
- Focus enhancement
- Motivation enhancement
- Increased sociability
- Mood lift
Negative
- Compulsive redosing
- Anxiety
- Paranoia
- Irritability
- Aggressiveness
- Talkativeness
- Time distortion
- Excessive talking
- Moodiness
Positive
- Increased libido
- Tactile enhancement
- Increased music appreciation
- Tracers
Negative
- Appetite suppression
- Light sensitivity
- Dehydration
- Disinhibition
- Increased sexuality
- Visual and auditory hallucinations