3-HO-PCE
Aliases: 3-oh-pce, 3-hydroxy pce, Hydroxyeticyclidine, 3hopce
Summary
3-Hydroxyeticyclidine (commonly known as 3-HO-PCE) is a novel synthetic dissociative substance of the arylcyclohexylamine chemical class. It produces potent, dose-sensitive dissociative, hallucinogenic and euphoric effects when administered. Unlike its close structural analog 3-HO-PCP, this compound has no precedent in the scientific literature before being offered on the research chemicals market in the 2010s.
Perspectives
“With a newer and better batch, 3-HO-PCE has truly shown itself as a powerful and remarkable dissociative. It is definitely warm, comfortable, and anesthetic, with pleasurable physical sensations. Less enjoyable is the total smothering of thought processes, of everything slowing to a halt.”
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 5-10mg | 10-15mg | 15-25mg | 25mg+ |
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 19-45 min | 30-60 min | 1-3 hrs | 2-3 hrs | 3-4 hrs |
| Insufflated | 4-15 min | 15-30 min | 1-3 hrs | 2-3 hrs | 3-4 hrs |
Effect Profile
4 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong dissociative depth and mania with moderate motor impairment and insight
Tolerance
Tolerance Decay
Modeled on typical arylcyclohexylamine patterns: rapid within‑week build, week‑scale decay. Data quality mostly anecdotal; adjust conservatively.
Cross-Tolerances
Effects
Aggregated from 4 Erowid experience reports