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    Disclaimer
    โš  PCP and its analogues are potent dissociatives with significant risk of psychosis, violent behavior, and overdose. Effects are highly unpredictable and dose-sensitive.
    ๐Ÿงช This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    3-HO-PCP

    Aliases: 3-oh-pcp, Hydroxyphencyclidine, 3hopcp

    Categories

    Dissociative Research-chemical
    3-HO-PCP structure

    Summary TheDrug.Wiki TripSit PsychonautWiki

    3-HO-PCP is a potent dissociative first synthesized in 1978. Uniquely among arylcyclohexylamines, it has appreciable ฮผ-opioid receptor activity in animal models, though the extent of opioid effects in humans remains unclear. Reports suggest it may produce more physical side effects (muscle soreness, flu-like symptoms) than related dissociatives, especially at higher doses. Due to its high potency, volumetric dosing is strongly recommended. Fentanyl test strips may produce false positives with this substance.

    Perspectives

    “This was in fact quite a decent experience, tempting a potential return.”

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 2-4mg 4-6mg 6-8mg 8mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 15-45 min 60-90 min 2.0-4.0 hrs 1.0-2.0 hrs 12.0 hrs 3.0-4.0 hrs
    Insufflated 4-19 min 30-60 min 2.0-3.0 hrs 1.0-2.0 hrs 12.0 hrs 3.0-4.0 hrs

    Tolerance

    Build-up develops with repeated use over days to weeks
    Reset 2โ€“4 weeks for noticeable reduction
    Cross-tolerance
    Ketamine Dextromethorphan PCP Methoxetamine 3-MeO-PCP 3-MeO-PCE 3-HO-PCE O-PCE

    Effects TheDrug.Wiki PsychonautWiki

    Positive
    • Physical euphoria
    • Pain relief
    • Stimulation
    • Creativity Enhancement
    Negative
    • Respiratory depression
    • Increased heart rate
    • Increased blood pressure
    • Increased perspiration
    • Seizure
    • Abnormal heartbeat
    • Erectile dysfunction
    Neutral
    • Physical disconnection
    • Difficulty urinating
    • Restless legs
    • Spontaneous bodily sensations
    • Sedation
    Positive
    • Cognitive euphoria
    • Anxiety suppression
    • Thought connectivity
    • Conceptual thinking
    • Immersion intensification
    Negative
    • Depersonalization
    • Derealization
    • Motor control loss
    • Compulsive redosing
    • Memory suppression
    • Thought disorganization
    • Cognitive disconnection
    • Dizziness
    • Delusion
    • Thought deceleration
    • Amnesia
    • Psychosis
    Neutral
    • Dissociation
    • Time distortion
    • Perspective distortion
    Positive
    • Perception of bodily lightness
    • Tactile enhancement
    • Increased music appreciation
    Negative
    • Tactile suppression
    • Disinhibition
    • Spatial disorientation
    • Pattern recognition suppression
    • Double vision
    • Dehydration
    • Appetite suppression
    • Visual acuity suppression
    • Auditory acuity suppression
    • Orgasm depression
    Neutral
    • Internal hallucination
    • Auditory hallucination
    • Auditory distortion
    • Scenery slicing
    • Changes in felt gravity
    • Visual disconnection
    • Olfactory hallucination
    • Optical sliding
    • Perspective hallucination
    • Tactile intensification
    • Visual processing deceleration

    Combinations TripSit

    Trip Reports Effect Index

    Drowning in Its Throat nervewing Comfortably Melty and Floaty froggie

    Helpful Links

    ๐Ÿ“˜ Experience Reports ๐Ÿ“– TripSit ๐Ÿ“– Bluelight ๐Ÿ“– PsychonautWiki ๐Ÿ“– The Drug Users Bible