4-CBC is a halogenated cathinone that acts as a monoamine transporter substrate with EC50 values similar to 4-CMC, indicating strong dopaminergic stimulation and moderate serotonergic activity. Halogenated cathinones produce oxidative stress in cardiomyocytes; rat hepatocyte studies indicate mitochondrial dysfunction at concentrations above 100 µM. Physiological risks include tachycardia, hypertension, mydriasis, bruxism, thermoregulatory dysregulation, chest tightness, and seizures. Harm reduction practices: use a milligram-accurate scale, start with half a common dose to gauge sensitivity, limit redosing intervals to minimum 3 hours, keep total session usage under 250 mg, maintain hydration with 250 ml isotonic drinks per hour, and take minimum 2-week breaks between sessions. Reagent tests produce bright yellow color with Marquis reagent similar to 4-CMC; confirm identity via GC-MS or HPLC when possible.
