4-EEC
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 3 corroborating sources
- 3 ROAs with full dose ladders
- duration data present
- 18 combo interactions documented
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
- 3 corroborating sources
- 3 ROAs with full dose ladders
- duration data present
- 18 combo interactions documented
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
Aliases: 4-ethylethcathinone
Summary
Pharmacology is presumed to involve mixed monoamine reuptake inhibition and releasing action with NET≈DAT>SERT, similar to 4-MEC but slightly less potent and longer lasting due to the ethyl para-substitution. Limited formal toxicology data exists; acute risks mirror other cathinones including tachycardia, hypertension, hyperthermia, vasoconstriction, bruxism, and potential serotonin syndrome when mixed with serotonergics. Hydration, temperature monitoring, and magnesium supplementation for jaw tension are advisable.
Dose Information
Dose basis. All ranges are anecdotal and likely vary with salt form (typically HCl) and individual sensitivity; always weigh doses on a 0.001 g scale and start low. User communities and harm‑reduction orgs note that cathinone potencies vary widely and products are often mis‑sold or adulterated; confirm identity with multi‑reagent testing or a lab check before dosing. Insufflation increases onset and compulsive redosing. Cathinone powders are caustic to nasal mucosa; use your own clean straw, crush finely, alternate nostrils, and rinse with saline before/after to reduce damage and infection risk. (Dose figures and this note are from Drugs.Wiki.)
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 75-125mg | 125-250mg | 250-350mg | 350mg+ |
| Insufflated | 30-60mg | 60-120mg | 120-200mg | 200mg+ |
| Rectal | 60-100mg | 100-180mg | 180-250mg | 250mg+ |
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 10-30 min | 20-40 min | 1-3 hrs | 1-2 hrs | 2.5-6.17 hrs |
| Insufflated | 1-5 min | 5-15 min | 1-3 hrs | 1-2 hrs | 2.1-5.33 hrs |
| Rectal | 5-15 min | 15-30 min | 1-3 hrs | 1-2 hrs | 2.33-5.75 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Moderate euphoria with mild stimulation and sensory enhancement, low empathy
Strong anxiety/jitters with moderate euphoria and focus, low stimulation
Add to PsychonautWiki Journal
The PsychonautWiki Journal logging app doesn't include every substance. To track 4-EEC there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:
4-EEC Source: SubstanceSearch (substancesearch.com) Oral dose (mg): threshold 40 · light 75-125 · common 125-250 · strong 250-350 · heavy 350+ Insufflated dose (mg): threshold 15 · light 30-60 · common 60-120 · strong 120-200 · heavy 200+ Rectal dose (mg): threshold 30 · light 60-100 · common 100-180 · strong 180-250 · heavy 250+ Oral duration: onset 10-30m · come-up 20-40m · peak 1-3h · offset 1-2h · total 2.5-6.17h · after-effects 2-24h Insufflated duration: onset 1-5m · come-up 5-15m · peak 1-3h · offset 1-2h · total 2.1-5.33h · after-effects 2-24h Rectal duration: onset 5-15m · come-up 15-30m · peak 1-3h · offset 1-2h · total 2.33-5.75h · after-effects 2-24h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 187.5 mg (Oral).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Rapid tolerance and strong redose urges are commonly reported with 4‑substituted cathinones; spacing sessions by at least 1–2 weeks helps reduce comedown severity and crash. Data are anecdotal and extrapolated from similar compounds.
Cross-Tolerances
Effects
- Stimulation
- Physical Euphoria
- Teeth Grinding
- Vasoconstriction
- Pupil Dilation
- Increased Heart Rate
- Temperature Regulation Suppression
- Cognitive Euphoria
- Empathy, Affection, and Sociability Enhancement
- Motivation Enhancement
- Focus Enhancement
- Compulsive Redosing
- Anxiety
- Motivation Suppression
- Thought Deceleration
- Irritability
- Thought Acceleration
- Increased Libido
- Tactile enhancement
- Increased music appreciation
- Tracers
- Appetite Suppression
- Dehydration
- Light sensitivity
- Disinhibition
Combinations
Cross-Check 4-EEC with another substanceHelpful Links
Report an issue or suggest an edit
Spotted incorrect or dangerous information, have a correction, a new study, or a useful addition for 4-EEC? Let us know. Reports are reviewed by moderators — this is not posted publicly.