About me 39 years old male 310lbs and 6foot 3inches tall Past drug experience: ALCOHOL: Drinking alcohol to the point of puking / spins / knows what itยs like to feel slurring speech drunk / intense buzz of alcohol done via shots and repeated cocktails MDMA: Tried 1 500mg pill of pure MDMA once at age 23, literally cam...
4-MEC
Well-documented
Well-documented
Multiple authoritative sources agree on dosing and effects.
- 4 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 18 combo interactions documented
- classified Research-chemical
Well-documented
Multiple authoritative sources agree on dosing and effects.
- 4 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 18 combo interactions documented
- classified Research-chemical
Aliases: Nrg-2, 4-methylethcathinone, 4mec
Summary
4-MEC is generally considered less potent than mephedrone, requiring approximately double the dose for comparable effects. It has a reputation for producing less intense euphoria but being more forgiving on the body. Intravenous use is particularly rough on veins and can cause vascular damage with chronic use.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 50-100mg | 100-200mg | 200mg | 200mg+ |
| Insufflated | 25-40mg | 40-100mg | 100-150mg | 150mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset |
|---|---|---|---|---|
| Oral | 20-60 min | 30-45 min | 1-2 hrs | 1-3 hrs |
| Insufflated | 5-10 min | 10-20 min | 1-2 hrs | 1-3 hrs |
| Intravenous | - | 1-2 min | 20-30 min | 1-2 hrs |
Effect Profile
22 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Validated against 22 Erowid trip reports
- Weighted by importance: core (×3), major (×2), minor (×1)
Empathogen
9.6
Extreme
10/10
Strong euphoria, stimulation, sensory enhancement, and empathy
Empathy / Social Openness
×3
9
empathy enhancement
increased sociability
Euphoria / Mood Elevation
×2
10
euphoria
mood lift
Stimulation
×1
10
stimulation
teeth grinding
Sensory Enhancement
×1
10
tactile enhancement
music enhancement
increased libido
Stimulant
6.8
Strong+
7/10
Strong euphoria, anxiety/jitters, and stimulation with mild focus
Stimulation / Energy
×3
8
stimulation
Euphoria / Mood Lift
×2
10
euphoria
mood lift
motivation enhancement
Focus / Productivity
×2
5
motivation enhancement
Anxiety / Jitters
×1
10
anxiety
teeth grinding
bruxism
sweating
Based on reports from:
Tolerance
Build-up
develops rapidly, often within a single session; compulsive redosing common
Reset
a few days for acute tolerance
Tolerance Decay
Full tolerance
1d
Half tolerance
7d
Baseline
~21d
Acute tolerance: develops within a single session โ the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Acute tolerance within a session is common; users report markedly diminished returns after initial doses and stronger comedowns with binges. Conservative spacing (โฅ2 weeks) is commonly advised in HR communities to limit cumulative harms; empirical pharmacodynamic tolerance half-life is not well established.
Cross-Tolerances
Effects
Aggregated from 22 Erowid experience reports
Positive Effects 8
Euphoria
81.8%
70%
Stimulation
72.7%
70%
Music Enhancement
50.0%
70%
Tactile Enhancement
40.9%
70%
Empathy
31.8%
70%
Focus Enhancement
22.7%
70%
Color Enhancement
18.2%
70%
Introspection
18.2%
70%
Adverse Effects 8
Nausea
40.9%
70%
Anxiety
36.4%
70%
Increased Heart Rate
31.8%
70%
Sweating
27.3%
70%
Headache
22.7%
70%
Pupil Dilation
22.7%
70%
Jaw Clenching
13.6%
70%
Confusion
13.6%
70%
Combinations
Cross-Check 4-MEC with another substanceCommunity Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.
Erowid 8 reports 6 neutral 2 cautionary visit
Dose Schedule: 0:00 4-mec 2mg insufflated 0:10 4-mec 6mg insufflated 0:30 4-mec 6mg insufflated 1:00 Caffiene 70mg Oral 2:55 4-mec 3mg insufflated 3:45 4-mec 4mg insufflated 4:05 4-mec 4mg insufflated To start off this report, I would like to introduce the reader to the history of my drug use.
I offer this in part as a corrective to my earlier experience report on this substance. Its been 3 days since my last and hopefully final binge on 4-MEC. I still have a little blood coming out of my congested nose when I blow, but the congestion and cold symptoms are finally easing off, and my mood swings have become t...
After reading online for quite some time about various cathinones/MDxx replacements, I decided to try my hand at 4-MEC after seeing a research chemical vendor offering it for an insanely low price. So it was, I ordered 2 grams of the substance.
We discovered 4-MEC when browsing a certain research chemical vendor's catalog. After reading some reports me and three friends decided that 4-MEC was worth the experiment, and so we bought three grams total and shared the compound between the four of us was going to be a very peculiar evening.
I've taken a whole lot of drugs, the only ones that would pertain to this trip report would be 6-APB, stims like methylphenidate and adderal, cocaine and dozens of $5 street ecstasy pills ranging from good to real shitty. I've had my share of 'rolls', just never had real MDMA.
Iยm a 45-year old man, with a 30-year long history of use of psychoactive substances, including most or all of the major psychedelics and stimulants, some dissociatives, and limited numbers of opiates, benzos, etc.
Recently, I ordered some MXE online. Knowing online vendors I was nowhere near surprised when I received 4-MEC instead of MXE. This drug was never of much interest to me; I know very little about its pharmacology, I typically do not like stimulant drugs, and I never saw any long lasting effects of this substance for th...
Bluelight 6 threads 6 neutral visit
Hi, I'm an early 30s 75kgish male. I've done 4-MEC before in increasing doses, because I'm a (lol) responsible drugs user, from <1mg allergy test, 10mg, 50mg test doses.
I am 39yo, 6-feet 3-inches tall and weigh 310lbs. I have never snorted any drug before trying 4-MEC today. I have not had alcohol or any other psychoactive substances in my system since december 2010. Received 4grams of 4-MEC / 4-Methylethcathinone from a good supplier; batch was very clean and close to pure.
Hi Guys I have spent a long time trying to find a trip reviews or even some good info on this drug but seems everywhere I look all I find is rubbish So a supplier who I have used for a long time with RC's and has allways supplied me with very good quality product has just got this into stock So I have ordered myslef 1g...
Substance: 2-(Ethylamino)-1-(4-methylphenyl)propan-1-one HCL or 4 MEC Purity: 99.80% Recent drug history: Mephedrone, Methylone, MDPV, MDMA, LSD, 2cb, 4-aco-dmt, MXE, 4-meo-pcp, Ketamine, Cocaine, GHB, GBL, 5-meo-mipt, 5-meo-dalt, aMT, 5-meo-dpt ( EDIT: Sorry to get you excited - this was indeed supposed to be 5-meo-di...
Hello ! my very first trip report goes as following : Body Weight : 75 kg Previous experiences with stimulants : ephedrine, cocaine hcl, cocaine freebase (experienced) Others : codeine, morphine, buprenorphine, DXM, Methoxetamine (experienced) Psychedelics : sclerotia (one time), LSA seeds (one time) No substance use i...
4-CMC 1st time 65MG hello all this is my first trip report ever, so bear with me. Alright so i acquired some 4-CMC aka Clephedrone aka 4-chloromethcathinone (4-CMC) via sample. I have 1 gram. I am 6"1 tall 160 lbs decently healthy. I do have a opiate/opiod addiction i treat with kratom and a benzodiazepine habit.
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