4-MMC
Aliases: Meow, Drone, M-cat, Bubble, Meow meow, 4-methylmethcathinone, 4mmc, mephedrone
Categories
Summary
Mephedrone is typically sold as white or off-white powder or crystals that clump from moisture. GC-MS surveys show frequent adulteration with other cathinones; multi-reagent testing (Marquis produces no reaction or slight fizz, Liebermann gives bright yellow) plus FT-IR is recommended. It is a potent monoamine releaser with a serotonin-to-dopamine ratio of approximately 1.22:1, producing stronger stimulation and shorter duration than MDMA. Plasma half-life averages 1.5-2.1 hours with active metabolites nor-mephedrone and 4-carboxy-mephedrone; users compensate by redosing every 30-90 minutes, markedly increasing cardiovascular load and hyponatremia risk. Case reports describe acute psychosis, rhabdomyolysis, severe peripheral vasoconstriction, and necrotising skin lesions after prolonged IV use.
Perspectives
“This was a very enjoyable experience, and one which confirmed the reputation of mephedrone for short term effect and the temptation to sustain the euphoric high via compulsive redosing.”
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 50-100mg | 100-200mg | 200-300mg | 300mg+ |
| Insufflated | 15-45mg | 45-80mg | 80-125mg | 125mg+ |
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects | Total |
|---|---|---|---|---|---|---|
| Oral | 15-45 min | 10-20 min | 30-90 min | 1-2 hrs | 2-24 hrs | 240-0 min |
| Insufflated | 5-15 min | 5-10 min | 15-30 min | 1-2 hrs | 2-24 hrs | 180-0 min |
| Rectal | 10-20 min | 10-15 min | 30-60 min | 1-2 hrs | 2-24 hrs | 120-0 min |
| Intravenous | 0-5 min | 2-5 min | 15-30 min | 45-90 min | 2-24 hrs | 120-0 min |
Tolerance
Effects
- Stimulation
- Spontaneous tactile sensations
- Teeth grinding
- Jaw clenching
- Vasoconstriction
- Increased perspiration
- Increased blood pressure
- Increased heart rate
- Difficulty urinating
- Body odor alteration
- Cognitive euphoria
- Empathy, affection, and sociability enhancement
- Motivation enhancement
- Anxiety suppression
- Analysis enhancement
- Empathy, love, and sociability enhancement
- Wakefulness
- Compulsive redosing
- Anxiety
- Cognitive fatigue
- Depression
- Irritability
- Thought deceleration
- Thought disorganization
- Time distortion
- Thought acceleration
- Ego inflation
- Increased libido
- Tactile enhancement
- Increased music appreciation
- Disinhibition
- Dehydration
- Appetite suppression
- Spontaneous physical sensations
- Vibrating vision
- Increase sexuality
- Visual and audiotory hallucinations itchiness