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    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    Afloqualone Limited data
    Limited data
    Sparse data. Doses and effects may be unreliable or untested.
    • 2 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • classified Tentative
    • classified Research-chemical

    Aliases: Aroft, Hq-495, Arofuto

    Depressant Research-chemical

    Summary dose.wiki TripSit

    Potent photosensitizer - sun/UV exposure can precipitate severe dermatitis; cover skin and use high-SPF sunscreen. Marked ataxia and motor incoordination appear at higher doses with increased risk of falls. Mixing with any other CNS depressant markedly increases risk of respiratory depression.

    Dose Information dose.wiki TripSit

    ROA Light Common Strong Heavy
    Oral 50-75mg 75-100mg 100-200mg 200mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects dose.wiki TripSit

    ROA Onset Peak Offset After Effects Total
    Oral 30-90 min 1.5-3 hrs 2-4 hrs 2-6 hrs 3-5 hrs

    Add to PsychonautWiki Journal

    The PsychonautWiki Journal logging app doesn't include every substance. To track Afloqualone there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:

    ⬇ Download import file Import this file as custom substances and you get "Afloqualone (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.
    Name
    Afloqualone
    Unit
    mg
    Description 
    Afloqualone
Source: SubstanceSearch (substancesearch.com)

Oral dose (mg): light 50-75 · common 75-100 · strong 100-200 · heavy 200+

Oral duration: onset 0.5-1.5h · peak 1.5-3h · offset 2-4h · total 3-5h · after-effects 2-6h

Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 87.5 mg (Oral).

    The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.

    Tolerance

    Build-up develops over 1–4 weeks of regular use
    Reset days to weeks depending on duration of use

    Tolerance Decay

    Full tolerance 3d Half tolerance 14d Baseline ~28d

    Time‑course estimates derive from community reports and general GABAergic class effects (anecdotal). Avoid daily use to prevent rapid tolerance and physiologic dependence.

    Cross-Tolerances

    Benzodiazepines
    50%
    Barbiturates
    50%
    Methaqualone
    70%
    Other GABA_A PAMs
    40%

    Effects dose.wiki TripSit

    Positive
    • Muscle relaxation
    • Physical euphoria
    • Anxiolytic
    • Muscle Relaxant
    Negative
    • Respiratory depression
    • Motor impairment
    Neutral
    • Sedation
    • Sedative
    • Dystaxia
    • Hypnotic
    Positive
    • Anxiety suppression
    • Dream potentiation
    • Reduced anxiety
    • Cognitive euphoria
    Negative
    • Motor control loss
    • Amnesia
    • Thought deceleration
    • Dizziness
    • Compulsive redosing
    • Constipation
    Positive
    • Increased libido
    • Tactile enhancement
    Negative
    • Disinhibition
    • Acuity suppression
    • Double vision
    Neutral
    • Dulled perception
    • Visual disconnection
    • Internal hallucination
    • Changes in gravity
    • Internal hallucinations
    Afloqualone's nerd page Pharmacology, chemical data, effect profiles, and more
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    Helpful Links

    📘 Experience Reports 📖 dose.wiki 📖 TripSit 📖 PsychonautWiki