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    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    Afloqualone Limited data
    Limited data
    Sparse data. Doses and effects may be unreliable or untested.
    • 2 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • classified Tentative
    • classified Research-chemical

    Aliases: Aroft, Hq-495, Arofuto

    Depressant Research-chemical

    Summary TheDrug.Wiki TripSit

    Potent photosensitizer - sun/UV exposure can precipitate severe dermatitis; cover skin and use high-SPF sunscreen. Marked ataxia and motor incoordination appear at higher doses with increased risk of falls. Mixing with any other CNS depressant markedly increases risk of respiratory depression.

    Dose Information TheDrug.Wiki TripSit

    ROA Light Common Strong Heavy
    Oral 50-75mg 75-100mg 100-200mg 200mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit

    ROA Onset Peak Offset After Effects Total
    Oral 30-90 min 1.5-3 hrs 2-4 hrs 2-6 hrs 3-5 hrs

    Tolerance

    Build-up develops over 1–4 weeks of regular use
    Reset days to weeks depending on duration of use

    Tolerance Decay

    Full tolerance 3d Half tolerance 14d Baseline ~28d

    Time‑course estimates derive from community reports and general GABAergic class effects (anecdotal). Avoid daily use to prevent rapid tolerance and physiologic dependence.

    Cross-Tolerances

    Benzodiazepines
    50%
    Barbiturates
    50%
    Methaqualone
    70%
    Other GABA_A PAMs
    40%

    Effects TheDrug.Wiki TripSit

    Positive
    • Muscle relaxation
    • Physical euphoria
    • Anxiolytic
    • Muscle Relaxant
    Negative
    • Respiratory depression
    • Motor impairment
    Neutral
    • Sedation
    • Sedative
    • Dystaxia
    • Hypnotic
    Positive
    • Anxiety suppression
    • Dream potentiation
    • Reduced anxiety
    • Cognitive euphoria
    Negative
    • Motor control loss
    • Amnesia
    • Thought deceleration
    • Dizziness
    • Compulsive redosing
    • Constipation
    Positive
    • Increased libido
    • Tactile enhancement
    Negative
    • Disinhibition
    • Acuity suppression
    • Double vision
    Neutral
    • Dulled perception
    • Visual disconnection
    • Internal hallucination
    • Changes in gravity
    • Internal hallucinations
    Afloqualone's nerd page Pharmacology, chemical data, effect profiles, and more
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