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    πŸ§ͺ This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    ALEPH Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 2 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • 20 combo interactions documented
    • classified Tentative
    • classified Research-chemical

    Aliases: Dot, Aleph-1, Para-dot

    Summary TheDrug.Wiki TripSit

    ALEPH (DOT) is a rare psychedelic amphetamine first synthesized by Alexander Shulgin and documented in PiHKAL. It belongs to the DOx family and exhibits highly erratic dose-response relationships between individuals. Effects are characterized by intellectual stimulation with minimal visual effects at common doses.

    Perspectives

    “The initial hints of action were physicalβ€”warming of first the legs, and then a comfortable warmth spread over the entire body. Intense intellectual stimulation, one that inspired the scribbling of some 14 pages of handwritten notes. Which is a pretty good record for an experience that is almost entirely non-verbal. The afterglow was benign and rich in empathy for everything. And by the sixth hour I was quite hungry.”

    Dose Information TheDrug.Wiki TripSit

    ROA Light Common Strong Heavy
    Oral 2-4mg 4-6mg 6-12mg 12mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 30 min 30-60 min 2-4 hrs 2-3 hrs 24 hrs 5-10 hrs

    Effect Profile

    3 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 6.1
    Strong 6/10

    Strong visuals with moderate body load, mild headspace

    Visual Intensity ×3
    10
    color enhancement drifting tracers visual enhancement pattern recognition enhancement brightened colour
    Headspace Depth ×3
    5
    conceptual thinking thought connectivity time distortion
    Auditory Effects ×1
    0
    Body Load / Somatic Effects ×1
    6
    vasoconstriction nausea increased heart rate
    Empathogen 6.1
    Strong 6/10

    Strong euphoria and sensory enhancement with moderate stimulation, low empathy

    Empathy / Social Openness ×3
    3
    empathy enhancement
    Euphoria / Mood Elevation ×2
    10
    physical euphoria cognitive euphoria euphoria body high
    Stimulation ×1
    6
    stimulation wakefulness increased heart rate
    Sensory Enhancement ×1
    8
    tactile enhancement color enhancement visual enhancement
    Stimulant 5.6
    Strong 6/10

    Strong euphoria and anxiety/jitters with mild stimulation and focus

    Stimulation / Energy ×3
    5
    stimulation wakefulness
    Euphoria / Mood Lift ×2
    10
    physical euphoria cognitive euphoria euphoria body high
    Focus / Productivity ×2
    4
    analysis enhancement thought acceleration
    Anxiety / Jitters ×1
    8
    anxiety increased heart rate vasoconstriction

    Tolerance

    Build-up develops over days to weeks of regular use
    Reset 3–7 days for acute; 1–3 weeks for full reset

    Tolerance Decay

    Full tolerance 1d Half tolerance 7d Baseline ~14d

    Pattern inferred from general classic psychedelic tolerance (rapid acute tolerance; partial cross-tolerance), sparse ALEPH-specific data; schedule β‰₯7–14 days between uses to reduce blunted effects.

    Cross-Tolerances

    Effects Erowid

    Aggregated from 3 Erowid experience reports

    Positive Effects 1

    Focus Enhancement 100.0% 70%

    Adverse Effects 0

    Combinations TripSit

    Cross-Check ALEPH with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.

    Erowid 2 reports 2 neutral visit
    This Chem Digs Deep neutral exp #111374

    Height: 5'5' Weight: 124lbs Body/fat: 16% Substance: DOT / Aleph-1 / 2,5-dimethoxy-4-methylthioamphetamine Dosage: 10mg ROA: Orally Before administration: Ate a sandwich 2.5 hours ago. Nothing since. Pre-loaded with 100mg Magnesium, 150mg ibuprofen, and 25mg diphenhydramine for anticipated bodyload.

    SomeoneWhoIsntSober
    A View Into Multitasking neutral exp #111064

    Just a short text on the very strange effects of this drug - most unlike any of the psychedelic amphetamines I've encountered. The night started with myself and a friend ingesting 12mg of DOT that were a gift from a friend who is a synthetic chemist.

    mantaraydrink
    Bluelight 1 thread 1 neutral visit
    Dot Aleph 1 First And Second Times Challenging Hebrew neutral

    Tasted this obscure wild card twice so far.At the time I have just gotten familiar with DOM and found "boy this is the shit,forget all other psychedelics!" (sound familiar BD & yaesutom?).So I knew the nature of the DO's (DOB as well),but besides the PIHKAL entries for the Alephs only MU's were in the literature.The un...

    scraped 2026-03-14

    PiHKAL / TiHKAL Shulgin

    PiHKAL #3: ALEPH

    “The initial hints of action were physicalβ€”warming of first the legs, and then a comfortable warmth spread over the entire body. Intense intellectual stimulation, one that inspired the scribbling of some 14 pages of handwritten notes. Which is a pretty good record for an experience that is almost entirely non-verbal. The afterglow was benign and rich in empathy for everything. And by the sixth hour I was quite hungry.”

    β€” Alexander Shulgin, PiHKAL (with 5 mg)

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