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    Armodafinil

    Aliases: Nuvigil, Waklert, Alertec, Artvigil, Provigil

    Summary TheDrug.Wiki Erowid TripSit PsychonautWiki

    (R)-Modafinil (also known as Armodafinil and by the brand names Nuvigil, Artvigil, and Waklert) is a eugeroic substance of the benzhydryl class. Armodafinil is the enantiopure formulation of modafinil (brand name Provigil). As opposed to the racemic formulation, which contains a 50/50 mix of both the (S) and (R) enantiomers, armodafinil consists of just the (R)-enantiomer of modafinil.

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 40-100mg 100-200mg 200-300mg 300mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 20-60 min 1-2.5 hrs 4-7 hrs 2-5 hrs 2-12 hrs 7.3-15.5 hrs

    Effect Profile

    20 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Validated against 20 Erowid trip reports
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Stimulant 7.5
    Intense 8/10

    Strong stimulation, focus, and anxiety/jitters with mild euphoria

    Stimulation / Energy ×3
    10
    stimulation wakefulness
    Euphoria / Mood Lift ×2
    5
    motivation enhancement
    Focus / Productivity ×2
    10
    focus enhancement memory enhancement motivation enhancement thought acceleration
    Anxiety / Jitters ×1
    10
    anxiety increased heart rate vasoconstriction sweating

    Tolerance

    Build-up minimal tolerance development in most users
    Reset not well established

    Tolerance Decay

    Full tolerance 14d Half tolerance 3d Baseline ~7d

    Users report some loss of effect with continuous daily use over weeks; spacing doses (e.g., weekends off) may slow tolerance. Empirical, anecdotal data only; no robust human PK/PD tolerance studies specific to armodafinil. Prioritise sleep hygiene to reduce compensatory dose escalation.

    Effects Erowid

    Aggregated from 20 Erowid experience reports

    Positive Effects 5

    Stimulation 65.0% 70%
    Focus Enhancement 55.0% 70%
    Euphoria 40.0% 70%
    Empathy 25.0% 70%
    Color Enhancement 20.0% 70%

    Adverse Effects 6

    Anxiety 50.0% 70%
    Confusion 45.0% 70%
    Increased Heart Rate 20.0% 70%
    Nausea 15.0% 70%
    Sweating 15.0% 70%
    Jaw Clenching 15.0% 70%

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