[Erowid Note: The dose described in this report is very high, potentially beyond Erowid's 'heavy' range, and could pose serious health risks or result in unwanted, extreme effects.
Baclofen
Well-documented
Well-documented
Multiple authoritative sources agree on dosing and effects.
- 6 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 15 combo interactions documented
- PubChem toxicity data
Well-documented
Multiple authoritative sources agree on dosing and effects.
- 6 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 15 combo interactions documented
- PubChem toxicity data
Aliases: Liofen, Ozobax, Kemstro, Lioresal, Gablofen
Summary
Baclofen (also known as Lioresal, Gablofen, Kemstro, Liofen) is a depressant substance of the gabapentinoid class. It is a derivative of GABA and is chemically related to phenibut, pregabalin, and gabapentin. It primarily acts as a GABAB receptor agonist.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 10-20mg | 20-50mg | 50-100mg | 100mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 30-75 min | 60-90 min | 1-2 hrs | 1.5-2.5 hrs | 3-6 hrs |
| Intrathecal | 15-45 min | - | - | - | 15-45 min |
Tolerance
Build-up
develops over weeks of daily use; withdrawal can cause seizures
Reset
1–2 weeks; must taper to avoid withdrawal
Tolerance Decay
Full tolerance
3d
Half tolerance
10d
Baseline
~14d
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
Aggregated from 20 Erowid and 5 Bluelight experience reports
Positive Effects 14
Sociability Enhancement
40.0%
82%
Anxiety Suppression
40.0%
80%
Euphoria
32.0%
85%
Stimulation
28.0%
75%
Sedation
24.0%
88%
Empathy
20.0%
95%
Love
20.0%
90%
Drowsiness
20.0%
85%
Music Enhancement
20.0%
80%
Contentment
20.0%
70%
Relaxation
20.0%
85%
Warmth
20.0%
80%
Libido Enhancement
20.0%
75%
Introspection
20.0%
70%
Adverse Effects 15
Hypersomnia
60.0%
82%
Nausea
28.0%
85%
Disinhibition
20.0%
95%
Bloating
20.0%
85%
Ataxia
20.0%
90%
Dizziness
20.0%
85%
Field Widening
20.0%
65%
Body Load
20.0%
75%
Vomiting
20.0%
85%
Dysphoria
20.0%
70%
Depression
20.0%
75%
Weakness
20.0%
90%
Fear
20.0%
75%
Headache
20.0%
70%
Sweating
16.0%
85%
Combinations
Cross-Check Baclofen with another substanceCommunity Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.
Erowid 8 reports 2 positive 4 neutral 2 cautionary visit
I found a bottle of Bacolfin and decided to give it a go because, I am that kind of person sorry if it offends you. At 7p.m. I took 40mgs total of four ten mg pills and went cleaning. Didn't feel anything 15 mins later at 7:15 besides the feeling of tiredness.
Subject: Like alcohol, but without the good aspects Years ago, I sustained a concussion from being punched in the head. It dramatically and permanently worsened my short-term memory and concentration. It also caused chronic emotional lability, anxiety, and occasional rage.
I came across Baclofen one day in 2005 when I ran out of weed and I really needed something to keep my mind off it, because I had no cash and no way of getting weed for a few days. I was searching my house. The only thing I found was a bottle of pills prescribed to my mom as muscle relaxers.
Over my life I have struggled with addictions of one sort or another. My entire family tree is littered with alcoholics and opiate abusers. By the age of 30 I was well on the way to becoming another casualty with alcohol abuse which was destroying my life, career and family.
My sister received a prescription for Baclofen for an injury she got at work but never finished the pills. Having suffered from alcoholism and other mental illness, I am in recovery and take Lithium, Seroquel and Ulcer medication, not to mention the various 'muscle relaxants and narcotics' for a hip injury.
I had suffered from moderately severe depression for a couple of years. I had been drinking heavily during this time. I was obsessed with the idea of dying...I wanted to be dead and had researched the lethal dosage of a few drugs and taken a dosage higher than that which I had read about.
This seems to be a higher dosage for baclofen. When it came on, I experienced a lot of dizziness, very comparable to the sought-after effects of alcohol. I think at my dosage I was right at the line where the effects can become so powerful they are uncomfortable.
Bluelight 2 threads 2 neutral visit
A bit of background: I've done shrooms, smoked pot, done coke and oxy and vicodin, had ambien, adderall, etc. I've had a decent amount of experience with benzos as well as alcohol. Baclofen has been compared to GHB and I have never had a chance to try that.
I first came upon this chemical in my mom's pill collection. I looked it up on erowid and bluelight, but couldn't find any info. This was about 2 years ago. In that time I've had much experience with the drug, as well as many other pharmaceuticals (like most people my age..19) On wikipedia it states that "Baclofen is b...
Pill Identifiers
28
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