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    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    Phenibut

    Aliases: Phgaba, Noofen, Bifren, Fenibut, Anvifen

    Categories

    Depressant Nootropic Research-chemical
    Phenibut structure

    Summary TheDrug.Wiki Erowid TripSit PsychonautWiki

    Phenibut is a GABA-B receptor agonist and gabapentinoid with anxiolytic and sedative effects. It has a delayed onset of 1.5-3 hours which can lead to accidental overdose from redosing. Combining with other depressants can cause severe CNS depression, unconsciousness, and potentially fatal respiratory depression. Withdrawal after regular use can be severe and dangerous, requiring gradual tapering. Not approved for medical use in most countries outside Russia and Eastern Europe.

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral BA ~65% 0.5-1g 1-2g 2-3.5g 3.5g+
    Rectal 0.5-1g 1-2g 2-3.5g 3.5g+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 1.5-3.0 hrs 1.5-3.0 hrs 3.0-4.0 hrs 4.0-6.0 hrs 6.0-24.0 hrs 4.0-10.0 hrs
    Rectal 30.0-60.0 hrs - 1.0-3.0 hrs - 1.0-24.0 hrs 4.0-10.0 hrs

    Tolerance

    Build-up develops rapidly within 2–5 days of daily use; high dependence potential
    Reset 7–14 days; withdrawal can be severe
    Cross-tolerance
    Alcohol GHB GBL Gabapentin Pregabalin

    Effects TheDrug.Wiki TripSit

    Positive
    • Physical euphoria
    • Muscle relaxation
    • Pain relief
    • Anxiolytic
    • Muscle Relaxant
    • Stimulation
    Negative
    • Headaches
    • Increased blood pressure
    • Increased perspiration
    • Muscle cramps
    • Nausea
    • Respiratory depression
    • Stomach cramps
    • Temperature regulation suppression
    Neutral
    • Sedation
    • Sedative
    • Dystaxia
    • Hypnotic
    • Difficulty urinating
    Positive
    • Anxiety suppression
    • Euphoria
    • Cognitive euphoria
    • Sociability enhancement
    • Empathy enhancement
    • Motivation enhancement
    • Focus enhancement
    • Empathy, love, and sociability enhancement
    Negative
    • Motor control loss
    • Cognitive impairment
    • Amnesia
    • Depression
    • Dizziness
    • Information processing suppression
    • Thought deceleration
    Positive
    • Increased libido
    • Increased music appreciation
    • Perception of bodily lightness
    • Tactile enhancement
    • Appetite enhancement
    Negative
    • Disinhibition
    • Dehydration
    • Double vision
    • Decreased libido
    Neutral
    • Dulled perception

    Combinations TripSit

    Helpful Links

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