Canket
Aliases: 2-fxe, 2f-o-pce, 2f-nendck, 2'-fluoro-2-oxo-pce
Categories
Summary
2F-NENDCK is a novel dissociative first identified in Canberra, Australia in August 2022. It is a positional isomer of FXE (3'-Fluoro-2-oxo-PCE), differing only by fluorine position. In April 2023, DrugsData.org revealed that all samples previously identified as FXE actually contained 2F-NENDCK. Most substances sold as ketamine, FXE, or MXE since 2017 may have been 2F-NENDCK. Effects last significantly longer than ketamine (4-6 hours) with reports of stronger visual distortions, minimal euphoria, greater disorientation, difficulty urinating, and next-day cognitive impairment described as feeling cloudy or foggy.
Dose Information
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects |
|---|---|---|---|---|---|
| Oral | 20-40 min | 30-60 min | 1.5-2.5 hrs | 2-3 hrs | 4-12 hrs |
| Insufflated | 5-15 min | 15-30 min | 1.5-2 hrs | 1.5-2 hrs | 4-12 hrs |
Tolerance
Build-up
develops with repeated use over days to weeks
Reset
2–4 weeks for noticeable reduction
Cross-tolerance
Effects
Positive
- Analgesia
- Stimulation
- Physical euphoria
- Pain relief
Negative
- Nausea
- Numbness
- Loss of balance
- Physical disconnection
- Difficulty urinating
- Sedation
Positive
- Minimal euphoria
Negative
- Cognitive impairment
- Disorientation
- Motor control loss
- Dizziness
- Confusion
- Depersonalization
- Derealization
- Dissociation
- Physical autonomy
Positive
- Perception of bodily lightness
Negative
- Double vision
- Pattern recognition suppression
- Tactile suppression
- Dehydration
- Spatial disorientation
- Disinhibition
- Visual distortions
- Visual disconnection
- Auditory distortion